early virologic response
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2020 ◽  
Vol 1 (2) ◽  
pp. 01-05
Author(s):  
Seba Atmane

The aim of the study is to show the prevalence and risk factors of HCV at our hemodialysis (HD) center , in a study carried out on chronic hemodialysis patients during the year 2019, we identified eight cases out of 87 patients infected with HCV, or 9%. The average age in this population is 48 years, dialysed for an average of 15 years. Viral infection was discovered on average 12.5 years after the start of hemodialysis, during a routine screening examination. In this series, the genotype 1b was found in 2 cases (25%). Seven patients were treated out of the eight HCV hemodialysis patients, received dual therapy with sofosbuvir 400mg and daclar 60 mg for three months, with an early virologic response. A study done during a previous period, between 2015 and 2018, in the same center, looking at the risk factors for HCV transmission: 11 cases out of 134 hemodialysis patients infected with HCV. Among these cases, we noted the following factors; Blood transfusion: 3 cases (27.2%), surgery: 4 cases (45.4%), dental care: 2 cases (18%), no obvious cause: 2 cases (9%). Serologically ; HCV antibodies positive: 11/134, i.e. an 8.2% seroprevalence, PCR-viral RNA was positive in 10 out of 11 patients, i.e. a prevalence of 7.4% by PCR, number of copies: Above 1.03x 1, 000,000 (100%), number of Logs: Sup to 3.32 (100%), negative PCR: 01 patient.


2018 ◽  
Vol 6 (2) ◽  
pp. 1-8
Author(s):  
Mohamed Darwish Ahmed Abd Alla ◽  
Saleh Ahmed Elibiary ◽  
Ramy Hassan Elshaboury ◽  
George Y. Wu ◽  
Reham M. Dawood ◽  
...  

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Hasan Vosoghinia ◽  
Abbas Esmaeilzadeh ◽  
Azita Ganji ◽  
Seyed Mousal-Reza Hosseini ◽  
Saeid Amel Jamehdar ◽  
...  

2015 ◽  
Vol 64 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Iwona Mozer-Lisewska ◽  
Katarzyna Zwolińska ◽  
Arleta Elżbieta Kowala-Piaskowska ◽  
Maciej Bura ◽  
Błażej Rozpłochowski ◽  
...  

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