The Role of Physical Therapy in the Combined Treatment of Patients with Lower Extremities Diabetic Angiopathies

One of the most disabling complications of diabetes mellitus is angiopathy of the lower extremities. Diabetic polyneuropathy and diabetic foot syndrome are closely associated with vascular complications of diabetes mellitus, which significantly aggravate the course of the disease and contribute to high mortality. Diabetic polyneuropathy and diabetic foot syndrome are closely associated with the diabetes mellitus vascular complications that significantly aggravate the course of the disease and contribute to high mortality. Despite the improvement in the results of pharmacotherapy of diabetes mellitus, the problem of treating its vascular complications is far from being solved. Traditionally, therapeutic physical training is used among the methods of non-drug treatment of diabetes mellitus and its complications. As a method of pathogenetic focus on many risk factors for the development of diabetes and its complications, physical therapy exercises contribute to the correction of the syndrome of hypodynamia, obesity, and muscle atrophy. At the same time, there is insufficient data on how exercise therapy affects the quality of life of patients, functional characteristics of walking and objective indicators of blood flow in the lower extremities. This review identifies the main approaches to the application, advantages and disadvantages of individual methods of therapeutic physical training in the correction of functional disorders in patients with lower extremities diabetic angiopathies. We can currently talk about the proven safety of the physical therapy use in patients with diabetic angiopathies. Meanwhile, the scientific data on the high efficiency of this method is still insufficient.

The use of the HELPER device for determining infrared radiation of the skin in the diagnosis of diabetic angiopathies

A HELPER device is offered for the early diagnosis and monitoring of patients with diabetic angiopathies. The device picks up the limb skin temperature gradient. The temperature gradient in the diabetics increases with the progress of diabetic angiopathies in comparison with normal subjects.

Serum fibronectin content in the patients suffering from type 1 diabetes mellitus with microangiopathies since the childhood and in the subjects presenting with obesity

Micro- and macroangiopathies are the main causes of disability and mortality among the patients suffering from diabetes mellitus. Endothelial dysfunction is the early and important condition preceding the development of diabetic angiopathies. The serum fibronectin content may be one of the markers of endothelial dysfunction. We have documented the enhanced serum fibronectin content in the patients suffering from type 1 diabetes mellitus with concomitant microangiopathies and in the subjects presenting with obesity. The rise in the serum fibronectin level correlated with the body mass index, parameters of carbohydrate and lipid metabolism. Alteration of these parameters discovered in the present study may be used as the markers of endothelial dysfunction associated with the above pathological conditions.

Hyperhomocysteinemia: a risk factor for vascular complications of diabetes

Vascular complications are a leading cause of reduced quality and longer life of patients with diabetes mellitus (DM). The mechanisms of development of these complications are not fully disclosed. It is known that in not all cases the occurrence and progression of diabetic angiopathies can be explained by traditional risk factors, such as hyperglycemia, arterial hypertension, smoking or dyslipidemia. Therefore, the search for the missing links in the pathogenesis of angiopathy remains an extremely urgent task.

Infusion of ozonized solutions in the treatment of diabetic angiopathies of lower extremities

For the application in surgical practice the treatment method of diabetic angiopathy of lower extremities is proposed involving the intravenous injection of ozonized solutions. The method proposed allowed to localize fast the pyo-necrotic process, to reduce the number of amputations, to decrease the terms of hospitalizations. The method is simple, it does not require special skills and is pathogenetically justified.