A Bayesian Approach for Determining the Relationship Between Various Elongate Mineral Particles (EMPs) Definitions

A variety of dimensions (lengths and widths) of elongate mineral particles (EMPs) have been proposed as being related to health effects. In this paper, we develop a mathematical approach for deriving numerical conversion factors (CFs) between these EMP exposure metrics and applied it to the Minnesota Taconite Health Worker study which contains 196 different job exposure groups (28 similar exposure groups times 7 taconite mines). This approach comprises four steps: for each group (i) obtain EMP dimension information using ISO-TEM 10312/13794 analysis; (ii) use bivariate lognormal distribution to characterize overall EMP size distribution; (iii) use a Bayesian approach to facilitate the formation of the bivariate lognormal distribution; (iv) derive conversion factors between any pair of EMP definitions. The final CFs allow the creation of job exposure matrices (JEMs) for alternative EMP metrics using existing EMP exposures already characterized according to the National Institute of Occupational Safety and Health (NIOSH)-defined EMP exposure metric (length >5 µm with an aspect ratio ≥3.0). The relationships between the NIOSH EMP and other EMP definitions provide the basis of classification of workers into JEMs based on alternate definitions of EMP for epidemiological studies of mesothelioma, lung cancer, and non-malignant respiratory disease.

A Bivariate Lognormal Response-Time Model for the Detection of Collusion Between Test Takers

A bivariate lognormal model for the distribution of the response times on a test by a pair of test takers is presented. As the model has parameters for the item effects on the response times, its correlation parameter automatically corrects for the spuriousness in the observed correlation between the response times of different test takers because of variation in the time intensities of the items. This feature suggests using the model in a routine check of response-time patterns for possible collusion between test takers using an estimate of the correlation parameter or a statistical test of a hypothesis about it. Closed-form expressions for the maximum-likelihood estimations of the model parameters and a Lagrange multiplier test for the correlation parameter are presented. As in any type of statistical decision making, results from such procedures should be corroborated by evidence from other sources, for example, results from a response-based analysis or observations during the test session. The effectiveness of the model in removing the spuriousness from correlated response times is illustrated using empirical response-time data.