conformational stabilization
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Metabolic and conformational stabilization of a VEGF-mimetic beta-hairpin peptide by click-chemistry

2021 ◽  
pp. 113575
Author(s):  
Lucia De Rosa ◽  
Domenica Capasso ◽  
Donatella Diana ◽  
Rachele Stefania ◽  
Rossella Di Stasi ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Beta Hairpin ◽  
Conformational Stabilization

scholarly journals Correction: Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides

Oncotarget ◽  
2019 ◽  
Vol 10 (34) ◽  
pp. 3203-3206
Author(s):  
Perry Tal ◽  
Shay Eizenberger ◽  
Elad Cohen ◽  
Naomi Goldfinger ◽  
Shmuel Pietrokovski ◽  
...  
Keyword(s):  
Therapeutic Approach ◽  
P53 Protein ◽  
Mutant P53 ◽  
Small Peptides ◽  
Conformational Stabilization

scholarly journals Conformational Stabilization and Rapid Labeling of a 29-Residue Peptide by a Small Molecule Reaction Partner

Biochemistry ◽  
2019 ◽  
Vol 58 (10) ◽  
pp. 1343-1353 ◽  
Author(s):  
Ethan D. Evans ◽  
Zachary P. Gates ◽  
Zhen-Yu J. Sun ◽  
Alexander J. Mijalis ◽  
Bradley L. Pentelute
Keyword(s):  
Small Molecule ◽  
Molecule Reaction ◽  
Rapid Labeling ◽  
Conformational Stabilization

Ligation-Enhanced π-Hole···π Interactions Involving Isocyanides: Effect of π-Hole···π Noncovalent Bonding on Conformational Stabilization of Acyclic Diaminocarbene Ligands

2018 ◽  
Vol 57 (11) ◽  
pp. 6722-6733 ◽  
Author(s):  
Alexander S. Mikherdov ◽  
Mikhail A. Kinzhalov ◽  
Alexander S. Novikov ◽  
Vadim P. Boyarskiy ◽  
Irina A. Boyarskaya ◽  
...  
Keyword(s):  
Π Interactions ◽  
Acyclic Diaminocarbene ◽  
Noncovalent Bonding ◽  
Conformational Stabilization

scholarly journals Conformational stabilization of a β-hairpin through a triazole–tryptophan interaction

2018 ◽  
Vol 16 (5) ◽  
pp. 787-795 ◽  
Author(s):  
Donatella Diana ◽  
Claudia Di Salvo ◽  
Veronica Celentano ◽  
Lucia De Rosa ◽  
Alessandra Romanelli ◽  
...  
Keyword(s):  
Hairpin Conformation ◽  
Conformational Stabilization ◽  
Aromatic Interaction

Triazole and indole rings stabilize a β-hairpin conformation through an aromatic–aromatic interaction.

scholarly journals Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
María A. Urbaneja ◽  
Lars Skjærven ◽  
Oscar Aubi ◽  
Jarl Underhaug ◽  
David J. López ◽  
...  
Keyword(s):  
Conformational Stabilization

Conformational stabilization of FOX–DNA complex architecture to sensitize prostate cancer chemotherapy

Amino Acids ◽  
2017 ◽  
Vol 49 (7) ◽  
pp. 1247-1254 ◽  
Author(s):  
Bin Chen ◽  
Huiqiang Wang ◽  
Zhun Wu ◽  
Bo Duan ◽  
Peide Bai ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Chemotherapy ◽  
Complex Architecture ◽  
Dna Complex ◽  
Conformational Stabilization

scholarly journals Conformational stabilization of isatin Schiff bases – biologically active chemical probes

RSC Advances ◽  
2017 ◽  
Vol 7 (17) ◽  
pp. 10070-10073 ◽  
Author(s):  
Andrey S. Smirnov ◽  
Dmitriy N. Nikolaev ◽  
Vlad V. Gurzhiy ◽  
Sergey N. Smirnov ◽  
Vitaliy S. Suslonov ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Chemical Probes ◽  
Active Compounds ◽  
Active Chemical ◽  
Conformational Stabilization

Two ways of conformation stabilization for isatin Schiff bases (group of biologically active compounds) are reported here: complexation with metals that stabilize E-conformer and substitution in the 4th position of isatin core stabilizing Z-form.

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