darzens reaction
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2020 ◽  
Vol 142 (2) ◽  
pp. 733-737 ◽  
Author(s):  
Stephen M. Bierschenk ◽  
Robert G. Bergman ◽  
Kenneth N. Raymond ◽  
F. Dean Toste
Keyword(s):  

2019 ◽  
Vol 14 (10) ◽  
pp. 1934578X1988440
Author(s):  
Kenichi Kobayashi ◽  
Kosaku Tanaka ◽  
Momoko Suzuki ◽  
Hiroshi Kogen

A catalytic asymmetric intramolecular Darzens reaction of 2-halomalonate derivatives was developed for the enantioselective preparation of chiral building blocks for epoxide-containing natural products. Among the screened catalysts, some phase-transfer catalysts gave the desired epoxide in moderate enantioselectivity, albeit in low yield. The epoxide product would be useful as versatile chiral building blocks for natural product synthesis.


2019 ◽  
Vol 60 (30) ◽  
pp. 1949-1951
Author(s):  
Juan Luo ◽  
Lanfang Hu ◽  
Minghao Zhang ◽  
Qiang Tang
Keyword(s):  

2018 ◽  
Vol 76 (3) ◽  
pp. 218-225 ◽  
Author(s):  
Kouji Kuramochi ◽  
Kenta Komori ◽  
Shoma Mizutani ◽  
Kazunori Tsubaki

2018 ◽  
Vol 16 (18) ◽  
pp. 3487-3494 ◽  
Author(s):  
Jinhui Shen ◽  
Yang Yang ◽  
Xiaoli Hou ◽  
Wenlei Zeng ◽  
Aimin Yu ◽  
...  

A new Darzens reaction of thioisatins and sulfonium salts has, for the first time, been reported. Some of the synthesized thiochromenone derivatives have been found to show good potent anticancer activities against six different cancer cell lines.


2017 ◽  
Vol 82 (23) ◽  
pp. 12647-12654 ◽  
Author(s):  
Guo-Li Chai ◽  
Jian-Wei Han ◽  
Henry N. C. Wong

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