COMPARISON OF VARIOUS EEG ELECTRODE PLACEMENT SYSTEMS TO DETECT EPILEPTIFORM ABNORMALITIES IN INFANTS

Background: Technical difficulties in placement of whole 10-20 electrode system is not uncommon in neonates and infants. Apart from the full channel many centers uses the modified and amplitude integrated EEG montages to identify seizures. Objective: Efficacy of standard, modified and amplitude integrated EEG electrode placement in infants to detect epileptiform abnormalities. Methods: All routine EEGs from June 2015 to April 2018 were taken. Age ≤ 2years at the time of recoding was the inclusion criteria. Digital EEG was performed according to standard 10-20 electrode placement system in all patients. Abnormal EEGs were reanalyzed in different montages like A) 21 electrodes- full channel, B) 10 electrodes- modified long distance and C)4 electrodes- (centro/parietal) respectively. Inter ictal epileptiform discharges (IEDs), seizures, periodic complexes and non-specific dysfunctions were tabulated in all patients. Full channel montages are considered bench mark for the analysis Results: A total 129 EEGs analyzed. A) Full channel standard 21 electrodes montages could identify IEDs in 35, non-specific electrophysiological dysfunction in 9 and burst-suppression pattern in 2 EEGs. B) Modified electrode placement consists of 10 electrodes could identify IEDs only in 26 EEGs and non-specific electro physiological dysfunction in 6 EEGs. A total of 28 nonconvulsive seizures (NCS) recorded in 6 patients; 20 numbers of NCS (71.4%) seen in modified electrode placement (B) and only 16 (57.1%) seen in centro/parietal electrode placement (C).. Conclusion: Standard EEG electrode placement has higher yield in detecting epileptiform abnormalities.

LOCALIZATION BY -PERIODIC COMPLEXES AND VIRTUAL STRUCTURE SHEAVES

In [12], Kim and the first author proved a result comparing the virtual fundamental classes of the moduli spaces of $\varepsilon $ -stable quasimaps and $\varepsilon $ -stable $LG$ -quasimaps by studying localized Chern characters for $2$ -periodic complexes. In this paper, we study a K-theoretic analogue of the localized Chern character map and show that for a Koszul $2$ -periodic complex it coincides with the cosection-localized Gysin map of Kiem and Li [11]. As an application, we compare the virtual structure sheaves of the moduli space of $\varepsilon $ -stable quasimaps and $\varepsilon $ -stable $LG$ -quasimaps.

Adult-Onset Subacute Sclerosing Panencephalitis With a 30-Year Latent Period

Subacute sclerosing panencephalitis (SSPE) is a rare progressive neuroinfectious disease due to a late complication of the measles virus. The hallmark clinical features of this disease include behavioral changes, myoclonus, dementia, visual disturbances, and pyramidal and extrapyramidal signs. The presence of characteristic high-amplitude periodic complexes on electroencephalography and raised antibody titers against measles in the cerebrospinal fluid help solidify the diagnosis. We present a case of a 40-year-old patient with SSPE who initially developed ophthalmologic manifestations 30 years after the primary measles infection. This case highlights both typical and atypical features of SSPE and provides a diagnostic framework for evaluating cases that fall outside of the standard scope of this disease.