An electrophysiological measure of tonotopic selectivity in normal-hearing humans and cats

We describe a non-invasive electrophysiological (EEG) measure of tonotopic selectivity and compare the results between humans and cats. Sequences of 50-ms tone-burst probes were presented at 1-second intervals against a continuous noise masker, and the averaged cortical onset response (COR) to the probe was measured using EEG electrodes placed on the scalp. The noise masker had a bandwidth of 1 or 1/8th octave, geometrically centred on 4000 Hz for humans and 8000 Hz for cats. Probe frequency was either -0.5, -0.25, 0, 0.25 or 0.5 octaves re 4000/8000 Hz. The COR was larger for probe frequencies more distant from the noise geometrical centre, and this effect was greater for the 1/8th-octave than for the 1-octave masker. This pattern broadly reflected the masked excitation patterns obtained psychophysically with similar stimuli in a companion paper. However, the positive signal-to-noise ratio used to obtain reliable COR measures meant that some aspects of the data differed from those obtained psychophysically, in a way that could be partly explained by the upward spread of the probe’s excitation pattern. We argue that although COR measures are affected by some factors that differ from those that influence psychophysical masked detection thresholds, they can reveal differences in the width of excitation patterns produced by different stimuli. We also argue that the paradigm may be effectively applied to cochlear-implant experiments in humans and animals.

Chromatic detection and discrimination in the periphery: A postreceptoral loss of color sensitivity

The peripheral visual field is marked by a deterioration in color sensitivity, sometimes attributed to the random wiring of midget bipolar cells to cone photoreceptors in the peripheral retina (Mullen, 1991; Mullen & Kingdom, 1996). Using psychophysical methods, we explored differences in the sensitivity of peripheral color mechanisms with detection and discrimination of 2-deg spots at 18-deg eccentricity, and find evidence for a postreceptoral locus for the observed loss in sensitivity. As shown before, observers' sensitivity to green was lower than to red in the periphery, although the magnitude of this effect differed across observers. These results suggest that the asymmetry in peripheral sensitivity occurs at a postreceptoral site, possibly a cortical one. In addition, noise masking was used to determine the cone inputs to the peripheral color mechanisms. The masked detection contours indicate that the red and green mechanisms in the periphery respond to the linear difference of approximately equally weighted L- and M-cone contrasts, just as they do in the fovea. Thus, if the midget retinal ganglion system is responsible for red/green color perception in the fovea, it is likely to be responsible at 18-deg eccentricity as well.

CS-Dependent Response Probability in an Auditory Masked-Detection Task: Considerations based on Models of Pavlovian Conditioning

Experimental studies were performed using a Pavlovian-conditioned eyeblink response to measure detection of a variable-sound-level tone (T) in a fixed-sound-level masking noise (N) in rabbits. Results showed an increase in the asymptotic probability of conditioned responses (CRs) to the reinforced TN trials and a decrease in the asymptotic rate of eyeblink responses to the non-reinforced N presentations as a function of the sound level of the T. These observations are consistent with expected behaviour in an auditory masked detection task, but they are not consistent with predictions from a traditional application of the Rescorla-Wagner or Pearce models of associative learning. To implement these models, one typically considers only the actual stimuli and reinforcement on each trial. We found that by considering perceptual interactions and concepts from signal detection theory, these models could predict the CS dependence on the sound level of the T. In these alternative implementations, the animal's response probabilities were used as a guide in making assumptions about the “effective stimuli”.