HIV-Associated benign lymphoepithelial parotid cysts: a rare case report

Approximately one to 10% of patients with Human Immunodeficiency virus (HIV) infection associated with salivary gland disease. The presence of Benign lymphoepithelial cyst (BLEC) in the parotid gland is an indicator of HIV Infection. The diagnosis is usually based on a clinical course and HIV confirmatory blood testing. We have reported a case of a 35 years old Nepalese male patient with swelling of the bilateral parotid glands and HIV associated BLEC confirmed by Rapid diagnostic test kit (Determine unigold stat pack).

Lymphoepithelial Cyst of the Pancreas: A Case Report

Lymphoepithelial cyst of the pancreas is a rare, non-malignant lesion with a good prognosis. It is filled with keratinized material, lined by squamous epithelium, and surrounded by lymphoid tissue. The imaging appearance of lymphoepithelial cyst varies and sometimes similar to other pancreatic lesions. Therefore, the preoperative imaging diagnosis of the lymphoepithelial cyst is difficult. We present a case of surgically diagnosed lymphoepithelial cyst of the pancreas focused on MR imaging features.

Lymphoepthelial cyst of submandibular region: a case report

Background The oral lymphoepithelial cyst (LEC) is a rare, soft-tissue, developmental cyst, initially presented by Gold in 1962 as a “branchial cleft cyst”. It may occur in the pancreas, tongue, neck, and other regions of the oral cavity. No study has been reported in Pakistan and Karachi reporting a case of lymphoepithelial cyst in the submandibular region. This rare case of LEC has been reported to help the clinicians to bring LEC into their differential diagnosis for lesions affecting the submandibular region. Case presentation We report a case of 57 years old female reported to the Maxillofacial OPD of a tertiary care hospital with the complaint of swelling on the right side of the neck for 3 weeks which was rapidly increasing in size. She was having difficulty in mastication. On extra-oral examination, there was swelling on the right side in the submandibular area. The overlying skin is normal with no evidence of pus and discharge. On palpation, the swelling was soft, non-tender, non-fluctuant, non-displaceable into the submandibular area. Lymph nodes were impalpable. Excision of the lesion performed under general anesthesia and biopsy revealed lymphoepithelial cyst associated with submandibular gland. Here we present an attention-grabbing case of swelling in the right submandibular region which was provisionally diagnosed as a malignant submandibular lymph node however later evidence histopathologically as a lymphoepithelial cyst of the submandibular gland. Conclusion An unusual cause of swelling in the neck is lymphoepithelial cysts. Submandibular gland appearance is not usual and can prove to be a clinical problem.

Lymphoepithelial cyst mimicking pancreatic cancer: a case report and literature review

Background Pancreatic lymphoepithelial cyst (LEC) is a rare nonmalignant cyst consisting of a benign collection of keratinizing squamous epithelial cells with lymphoid tissue. Diagnosing LEC preoperatively is considered difficult because of its non-specific clinical features; therefore, LEC is generally treated the same as a malignant tumor. Case presentation Our case was a 65-year-old man who underwent pancreatoduodenectomy 3 years previously for carcinoma arising from the ampulla of Vater. A pancreatic mass in the remnant pancreatic tail was detected through follow-up abdominal contrast-enhanced computed tomography (CT). This revealed two adjacent ring-enhanced masses that had been in tight contact with the left diaphragm and were enlarged. The tumors had high signal intensity in diffusion-weighted images of magnetic resonance imaging, and fluorodeoxyglucose-positron emission tomography (FDG-PET) showed abnormal uptake (standardized uptake value maximum: 17.4). Therefore, we conducted a partial resection of the remnant pancreas with concomitant resection of the left diaphragm. Microscopically, one of the tumors revealed rare fragments of apparently benign squamous epithelium on a background of keratinous debris, cyst contents, and scattered lymphocytes, and the adjacent mass revealed infiltrated neutrophils. The histopathological diagnosis was an LEC with chronic abscess. The patient recovered uneventfully and was discharged on postoperative day 10. Conclusions We reported a rare case of LEC with chronic abscess that was positively visualized on FDG-PET. When a pancreatic malignancy cannot be excluded, surgical resection is considered inevitable.

Lymphoepithelial cyst in the pancreatic accessory spleen：A case report

Lymphoepithelial cyst (LEC)is a rare disease. Clear diagnostic criteria have not been established, and the number of cases is expected to increase in the future. In particular, LEC in the pancreatic accessory spleen has not been reported in the past, and this report documents it for the first time.