scholarly journals Patterns of Transfusion Transmitted Infection in Past Ten Years Among Voluntary Blood Donors In Chennai- A Cross Sectional Study

2012 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
S.T. Radhiga
Keyword(s):  
Blood Donors ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Transfusion Transmitted Infection

scholarly journals Analysis of the profile of blood donors in a blood bank of a private medical college of Kolkata

2017 ◽  
Vol 4 (10) ◽  
pp. 3899 ◽  
Author(s):  
Debdutta Haldar ◽  
Kunal Kanti Majumdar ◽  
Shilpa Karir ◽  
Arun Kumar Chakraborty ◽  
Ankita Dey ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
The Body ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Male Predominance ◽  
Medical College ◽  
Transfusion Transmitted Infection

Background: Blood is the only oxygen transporter in the body and is crucial in saving lives. Research has failed to find a true substitute for blood and blood components and depends on human donors. There are several infectious and non-infectious risks associated with transfusion. An unsafe transfusion is very costly from both human and economic points of view. In that perspective the present study is aimed to assess the profile of blood donors. The objectives of the study were to assess the profile of blood donors as per records of Blood Bank of a private medical college of Kolkata and to find out the prevalence and trends of transfusion transmitted infections among those donors.Methods: A record based cross sectional study was conducted for the period May 2013 to April 2016 at Blood Bank of a private medical college and information regarding 5383 blood donor’s profile were collected and analysed. Results: The total donors were found to be 5383 out of which (87.72%) were voluntary donors and (12.28%) replacement donors. The donors had a male predominance (79.84%). The most available blood group was B+ (49.42%) and the least available blood group was A- (0.38%). The commonest transfusion transmitted infection was Hepatitis B (1.11%) followed by Hepatitis C (0.28%) and HIV (0.21%). The transfusion transmitted infections (TTI) shows a decreasing trend over the 3 years. Conclusions: The voluntary donors have increased over the 3 years but there is always a male predominance. The pattern of TTIs in the blood bank depicts the national trend too. 

scholarly journals Epidemiology of Transfusion Transmitted Infection among Patients with β-Thalassaemia Major in Pakistan

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Rizwan Ahmed Kiani ◽  
Muhammad Anwar ◽  
Usman Waheed ◽  
Muhammad Javaid Asad ◽  
Saleem Abbasi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Thalassaemia Major ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Transfusion Transmitted Infection ◽  
Blood Banks ◽  
The World ◽  
Chemiluminescent Immunoassay ◽  
Medical University

Introduction. Transfusion Transmitted Infections (TTIs) continue to be a major risk in transfusions in many parts of the world. The transfusion-dependent β-thalassaemia patients are particularly at risk of acquiring TTIs. The current study was undertaken to estimate the prevalence of TTIs in transfusion-dependent β-thalassaemia patients. Material and Methods. A cross-sectional study of 1253 multitransfused thalassaemia major patients was conducted in five different centres of Islamabad, Rawalpindi, and Karachi. The study subjects were screened for HIV, HCV, and HBV. The screening was performed at two centres: Department of Pathology, Shaheed Zulfiqar Ali Bhutto (SZAB) Medical University, and Blood Transfusion Services, Jinnah Postgraduate Medical Centre, from July to December 2015. The confirmatory screening was performed by Chemiluminescent Immunoassay (CLIA). Results. Out of the 1253 multiple transfused patients, 317 (25.3%) were infected with TTIs. HCV was positive in 273 cases (21.7%), HBV in 38 cases (3.0%), and HIV in 6 cases (0.5%). Conclusion. HCV was the leading TTI in multitransfused thalassaemia major patients in the study. Presence of HIV in thalassaemia patients is a recent disturbing development in Pakistan. Improved regulation of blood banks including use of internationally or nationally evaluated kits will bring down the incidence of TTIs in transfusion-dependent β-thalassaemia patients. More stringent behavioral and serological pretransfusion screening of blood for TTIs must be implemented in blood banks.

scholarly journals Prevalence of urogenital, anal, and pharyngeal infections with Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium: a cross-sectional study in Reunion island

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Mycoplasma Genitalium ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Urogenital Infection ◽  
High Prevalence

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.

scholarly journals Splenectomy and its relation to non-transfusion-transmitted infection in thalassemic patients

2016 ◽  
Vol 46 (3) ◽  
pp. 134
Author(s):  
Mururul Aisyi ◽  
Alan Roland Tumbelaka ◽  
Bulan Ginting Munthe ◽  
Bambang Madiyono
Keyword(s):  
Risk Factors ◽  
Common Cold ◽  
Severe Infection ◽  
Cross Sectional Study ◽  
Control Group ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Transfusion Transmitted Infection ◽  
Common Group ◽  
Level Of Significance

Background Splenectomy has been associated with an increasedsusceptibility to infection. Overwhelming postspelenectomy infec-tion (OPSI) can lead to high mortality. Decreased IgM and tuftsinconcentration on splenectomized patients seems to play a role ininfection’s susceptibility. Many studies have been performed todetermine the risk factors of infection in thalassemic patients.Objective To find out morbidity patterns and risk factors for pre-dicting the likelihood of infection in splenectomized thalassemicpatients.Methods A retrospective cross sectional study was conducted onconfirmed thalassemic children who came to Department of ChildHealth, Cipto Mangunkusumo Hospital within the period of 1973-2003. Splenectomized patients were categorized as cases groupand non-splenectomized patients as control group. Risk factors fordevelopment of common cold and diarrhea were analyzed usingchi-square test with level of significance <0.05.Results A total of 300 thalassemic patients, 100 of them were sple-nectomized, were enrolled in this study. The 15-year-age group orabove is the most common group underwent splenectomy (35%).Common cold is the most common mild infection in both splenec-tomized group (75%) and non-splenectomized (71%). A significantassociation was found between the risk of infection and splenec-tomy in thalassemic patients (OR=3.8;CI=2.2;6.62; P=0.000). As-sociation between time after splenectomy and frequency of com-mon cold in thalassemia was significant (OR=2.85;CI=1.16;7.14;P=0.011). Severe infection and acute diarrhea were considerednot significantly different between the two groups.Conclusion Splenectomy in thalassemia can increase the sus-ceptibility of non-transfusion-transmitted mild infection. Furtherstudy is needed to elaborate this finding

scholarly journals Demographics and health profile on precursors of non-communicable diseases in adults testing for HIV in Soweto, South Africa: a cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e030701 ◽  
Author(s):  
Kathryn L Hopkins ◽  
Khuthadzo Hlongwane ◽  
Kennedy Otwombe ◽  
Janan Dietrich ◽  
Mireille Cheyip ◽  
...  
Keyword(s):  
South Africa ◽  
Health Outcomes ◽  
Communicable Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Infected People ◽  
Sexually Transmitted ◽  
Group Sex

ObjectivesThis cross-sectional study investigated the burden of HIV-non-communicable disease (NCD) precursor comorbidity by age and sex. Policies stress integrated HIV-NCD screenings; however, NCD screening is poorly implemented in South African HIV testing services (HTS).SettingWalk-in HTS Centre in Soweto, South Africa.Participants325 voluntary adults, aged 18+ years, who provided written or verbal informed consent (with impartial witness) for screening procedures were enrolled.Primary and secondary outcomesData on sociodemographics, tuberculosis and sexually transmitted infection symptoms, blood pressure (BP) (≥140/90=elevated) and body mass index (<18.5 underweight; 18.5–25.0 normal; >25 overweight/obese) were stratified by age-group, sex and HIV status.ResultsOf the 325 participants, the largest proportions were female (51.1%; n=166/325), single (71.5%; n=231/323) and 25–34 years (33.8%; n=110/325). Overall, 20.9% (n=68/325) were HIV infected, 27.5% (n=89/324) had high BP and 33.5% (n=109/325) were overweight/obese. Among HIV-infected participants, 20.6% (14/68) had high BP and 30.9% (21/68) were overweight/obese, as compared with 29.3% (75/256) and 12.1% (31/256) of the HIV-uninfected participants, respectively. Females were more likely HIV-infected compared with males (26.5% (44/166) vs 15.1% (24/159); p=0.012). In both HIV-infected and uninfected groups, high BP was most prevalent in those aged 35–44 years (25% (6/24) vs 36% (25/70); p=0.3353) and >44 years (29% (4/14) vs 48% (26/54); p=0.1886). Males had higher BP than females (32.9% (52/158) vs 22.3% (37/166); p=0.0323); more females were overweight/obese relative to males (45.8% (76/166) vs 20.8% (33/159); p<0.0001). Females were more likely to be HIV infected and overweight/obese.ConclusionAmong HTS clients, NCD precursors rates and co-morbidities were high. Elevated BP occurred more in older participants. Targeted integrated interventions for HIV-infected females and HIV-infected people aged 18–24 and 35–44 years could improve HIV public health outcomes. Additional studies on whether integrated HTS will improve the uptake of NCD treatment and improve health outcomes are required.

scholarly journals Tattooing and risk for transfusion-transmitted diseases: The role of the type, number and design of the tattoos, and the conditions in which they were performed

2002 ◽  
Vol 128 (1) ◽  
pp. 63-71 ◽  
Author(s):  
S. DE A. NISHIOKA ◽  
T. W. GYORKOS ◽  
L. JOSEPH ◽  
J.-P. COLLET ◽  
J. D. MACLEAN
Keyword(s):  
Odds Ratio ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Type Number ◽  
Sectional Study ◽  
Cross Sectional ◽  
B Virus ◽  
And Performance ◽  
Performance Conditions

Tattoos have been shown to be associated with transfusion-transmitted diseases (TTDs), particularly hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Very little is known about the association between different categories of tattoos and TTDs. In a cross-sectional study in Brazil, we studied 182 individuals with tattoos and assessed the odds of testing positive for a TTD according to tattoo type, number, design and performance conditions. Major findings were significant associations between an increasing number of tattoos and HBV infection (odds ratio (OR) of 2·04 for two tattoos and 3·48 for [ges ] 3 tattoos), having a non-professional tattoo and testing positive for at least one TTD (OR = 3·25), and having [ges ] 3 tattoos and testing positive for at least one TTD (OR = 2·98). We suggest that non-professional tattoos and number of tattoos should be assessed as potential deferral criteria in screening blood donors.

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