scholarly journals Epidemiology of Transfusion Transmitted Infection among Patients with β-Thalassaemia Major in Pakistan

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Rizwan Ahmed Kiani ◽  
Muhammad Anwar ◽  
Usman Waheed ◽  
Muhammad Javaid Asad ◽  
Saleem Abbasi ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Thalassaemia Major ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Transfusion Transmitted Infection ◽  
Blood Banks ◽  
The World ◽  
Chemiluminescent Immunoassay ◽  
Medical University

Introduction. Transfusion Transmitted Infections (TTIs) continue to be a major risk in transfusions in many parts of the world. The transfusion-dependent β-thalassaemia patients are particularly at risk of acquiring TTIs. The current study was undertaken to estimate the prevalence of TTIs in transfusion-dependent β-thalassaemia patients. Material and Methods. A cross-sectional study of 1253 multitransfused thalassaemia major patients was conducted in five different centres of Islamabad, Rawalpindi, and Karachi. The study subjects were screened for HIV, HCV, and HBV. The screening was performed at two centres: Department of Pathology, Shaheed Zulfiqar Ali Bhutto (SZAB) Medical University, and Blood Transfusion Services, Jinnah Postgraduate Medical Centre, from July to December 2015. The confirmatory screening was performed by Chemiluminescent Immunoassay (CLIA). Results. Out of the 1253 multiple transfused patients, 317 (25.3%) were infected with TTIs. HCV was positive in 273 cases (21.7%), HBV in 38 cases (3.0%), and HIV in 6 cases (0.5%). Conclusion. HCV was the leading TTI in multitransfused thalassaemia major patients in the study. Presence of HIV in thalassaemia patients is a recent disturbing development in Pakistan. Improved regulation of blood banks including use of internationally or nationally evaluated kits will bring down the incidence of TTIs in transfusion-dependent β-thalassaemia patients. More stringent behavioral and serological pretransfusion screening of blood for TTIs must be implemented in blood banks.

scholarly journals Major Congenital Malformations Among The Newborns in BSMMU Hospital

1970 ◽  
Vol 40 (1) ◽  
pp. 7-12 ◽  
Author(s):  
K Fatemaq ◽  
F Begum ◽  
N Akter ◽  
SMM Zaman
Keyword(s):  
Congenital Anomalies ◽  
Congenital Malformations ◽  
Cross Sectional Study ◽  
Obstetrics And Gynecology ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Major Congenital Malformations ◽  
Medical University ◽  
Recorded Diagnosis

Congenital anomalies make an important contribution to infant mortality and they remain a leading cause of death in many countries of the world. Many babies also died in our country due to congenital anomalies. So this study was done to find out proportion, types of congenital anomalies at birth and immediate outcome of anomalous neonates. This cross sectional study was carried out in the department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital Shahbagh, Dhaka during the period January 2007 to December 2007. All the women giving birth to babies with congenital anomalies during this period were included. Types of congenital anomalies in neonates were recorded. Diagnosis of congenital anomalies was based on ultrasonography and clinical evaluation of the newborn was done by experienced neonatologist. During the study period 1630 patients delivered, of which 60 had congenitally malformed babies making the occurance of 3.68%. Neural tube defect was found to be the commonest (33.33%) type of anomaly. Among the most frequent NTD was hydrocephalus. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9955 BMJ 2011; 40(1): 7-12

scholarly journals Prevalence of urogenital, anal, and pharyngeal infections with Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium: a cross-sectional study in Reunion island

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Mycoplasma Genitalium ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Urogenital Infection ◽  
High Prevalence

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.

scholarly journals Exploring Health Literacy in Medical University Students of Chongqing, China: A Cross-Sectional Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0152547 ◽  
Author(s):  
Yan Zhang ◽  
Fan Zhang ◽  
Ping Hu ◽  
Wenjie Huang ◽  
Lu Lu ◽  
...  
Keyword(s):  
Health Literacy ◽  
University Students ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical University

A cross-sectional study of growth, puberty and endocrine function in patients with thalassaemia major in Hong Kong

1995 ◽  
Vol 31 (2) ◽  
pp. 83-87 ◽  
Author(s):  
E. Y. W. KWAN ◽  
A. C. W. LEE ◽  
A. M. C. LI ◽  
S. C. F. TAM ◽  
C. F. CHAN ◽  
...  
Keyword(s):  
Hong Kong ◽  
Cross Sectional Study ◽  
Endocrine Function ◽  
Thalassaemia Major ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association between obesity and depression in patients with diabetes mellitus type 2; a study protocol

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 7 ◽  
Author(s):  
Eduardo De la Cruz-Cano ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Emilio Reyes-Ramos ◽  
Thelma Beatriz Gonzalez-Castro ◽  
Isela Juarez-Castro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Diabetes Mellitus Type 2 ◽  
Cross Sectional Study ◽  
Diabetes Mellitus Type ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Patients With Diabetes

Background: Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 diabetes mellitus that present other health problems (such as hypertension and obesity). The aim of this study protocol is to determine if obesity increases the risk for depression in patient with diabetes type 2.Methods: The analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).The studies suitable for inclusion will be assessed by the Newcastle-Ottawa Scale (NOS) to determine their methodological quality. To identify the studies of interest, we will search on PubMed and EBSCO databases. We will use the following keyword combinations: "Diabetes Mellitus type 2 AND obesity AND depression", "depression AND Diabetes Mellitus type 2", "Diabetes Mellitus type 2 AND body mass index cross sectional study", "depression AND obesity cross-sectional study". Causes for exclusion will be publications that studied patients diagnosed with diabetes mellitus type 1; articles that focused on the treatment and complications of diabetes mellitus type 2; publications that have studied other clinical or psychiatric conditions (for instance, seizure disorder or history of schizophrenia, bipolar disorder, psychotic symptoms or dementia).Conclusion: The results of this study will form the basis for a better understanding of the association between obesity and depression in patients with diabetes mellitus type 2, and will allow development of prediction tools and better interventions. It is evident that several modifiable and non-modifiable risk factors play an important role in the pathogenesis of diabetes among population. Currently, evidence for the deleterious effects of diabetes mellitus type 2 are based on cross-sectional or other observational designs. Therefore, this study will have important implications for future research and public health guidance.

scholarly journals Splenectomy and its relation to non-transfusion-transmitted infection in thalassemic patients

2016 ◽  
Vol 46 (3) ◽  
pp. 134
Author(s):  
Mururul Aisyi ◽  
Alan Roland Tumbelaka ◽  
Bulan Ginting Munthe ◽  
Bambang Madiyono
Keyword(s):  
Risk Factors ◽  
Common Cold ◽  
Severe Infection ◽  
Cross Sectional Study ◽  
Control Group ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Transfusion Transmitted Infection ◽  
Common Group ◽  
Level Of Significance

Background Splenectomy has been associated with an increasedsusceptibility to infection. Overwhelming postspelenectomy infec-tion (OPSI) can lead to high mortality. Decreased IgM and tuftsinconcentration on splenectomized patients seems to play a role ininfection’s susceptibility. Many studies have been performed todetermine the risk factors of infection in thalassemic patients.Objective To find out morbidity patterns and risk factors for pre-dicting the likelihood of infection in splenectomized thalassemicpatients.Methods A retrospective cross sectional study was conducted onconfirmed thalassemic children who came to Department of ChildHealth, Cipto Mangunkusumo Hospital within the period of 1973-2003. Splenectomized patients were categorized as cases groupand non-splenectomized patients as control group. Risk factors fordevelopment of common cold and diarrhea were analyzed usingchi-square test with level of significance <0.05.Results A total of 300 thalassemic patients, 100 of them were sple-nectomized, were enrolled in this study. The 15-year-age group orabove is the most common group underwent splenectomy (35%).Common cold is the most common mild infection in both splenec-tomized group (75%) and non-splenectomized (71%). A significantassociation was found between the risk of infection and splenec-tomy in thalassemic patients (OR=3.8;CI=2.2;6.62; P=0.000). As-sociation between time after splenectomy and frequency of com-mon cold in thalassemia was significant (OR=2.85;CI=1.16;7.14;P=0.011). Severe infection and acute diarrhea were considerednot significantly different between the two groups.Conclusion Splenectomy in thalassemia can increase the sus-ceptibility of non-transfusion-transmitted mild infection. Furtherstudy is needed to elaborate this finding

scholarly journals Perception of Newcomers Regarding Learning English and Culture in Canada

2019 ◽  
Vol 12 (10) ◽  
pp. 86
Author(s):  
Shahla Sattar Khan ◽  
Mehmet Takkac
Keyword(s):  
Second Language ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Sectional Study ◽  
Cross Sectional ◽  
Language Play ◽  
New Immigrants ◽  
The World ◽  
Points Of View ◽  
Learning English

There are some factors, which are motivational, and on the other hand, there are many challenges that may cause hindrance for learning English as a second language. Therefore, the main objective is to assess perception regarding factors for learning English as a second language, especially among new immigrants. This was a cross-sectional study conducted at a Polycultural center, Canada during the period of June-2017 to July-2017. The results of the study reinforced that new immigrants face challenges while learning English. Almost more than half the participants said that they find difficulty in understanding majority words. Regarding learning culture, two-thirds mentioned that the learning about culture gives them different points of view about the world and develops their critical thoughts. However, the socio-demographic characteristics like age, native language, play an important role in learning English.

scholarly journals Substance use and associated factors and associated factors among preparatory school students in Nekemte town western Ethiopia; school based a cross- sectional study

2020 ◽  
Author(s):  
Markos Desalegn Beyene ◽  
Robsan Gudeta Getachew ◽  
Workineh Diriba Gemechu
Keyword(s):  
Substance Use ◽  
Associated Factors ◽  
Cross Sectional Study ◽  
Male Students ◽  
Sectional Study ◽  
School Students ◽  
Cross Sectional ◽  
Preparatory School ◽  
School Based ◽  
The World

Abstract Background: Millions of people throughout the world are using substances such as alcohol, nicotine, cocaine, methamphetamine, morphine, marijuana, heroin and many others. Substance use by people in all parts of the world, particularly adolescents, has long been of scientific, political and public concern. Objective: -the main aim of this study was to prevalence of substance use & associated factors among Nekemte preparatory school students in 2019. Methodology:-. School based cross-sectional study was conducted among students at Nekemte preparatory school from March 20-30, 2018. Multistage stratified sampling method was employed to select 372 study participants. Collected data was cleaned and entered in to Epi info version 3.5.3 and transported to SPSS (statistical package for social sciences) version 20 for analysis. Descriptive statistics and logistic regression was done to indentify factors associated with substance use in the study area. Result: The overall prevalence of current substance use was (19.1%). Being male students [AOR, 95%CI; 4.64(2.18, 9.75)], ever encountered pressure from friends to use substances [AOR, 95% CI; 2.61(1.03, 6.63)], having substance user parents [AOR, 95%CI; 6.4(2.87, 14.30)] and having many substance user friends [AOR, 95%CI; 6.2(2.82, 13.75)] were significantly associated with substance use among students in the study area. Conclusion & Recommendation: The current prevalence of substance use among preparatory school students of this study area was low. The most commonly used substances were alcohol, khat and tobacco. Being male students, pear pressure, living with parents use substance & friends were found to affect substance use among Nekemte preparatory school students. Awareness creation sessions; Information, Education &Communication intervention should be intensified to further reduce Substance use among students.

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