scholarly journals INFLUENCE OF STOKES DRIFT ON SALT WEDGE INTRUSION EVALUATED USING FULLY-NONLINEAR AND STRONGLY-DISPERSIVE WAVE EQUATIONS

2011 ◽  
Vol 1 (32) ◽  
pp. 34 ◽  
Author(s):  
Keisuke Nakayama ◽  
Tetsuya Shintani ◽  
Taro Kakinuma ◽  
Yasuyuki Maruya ◽  
Yoshinori Yonome ◽  
...  
Keyword(s):  
Internal Wave ◽  
Surface Waves ◽  
Wave Equations ◽  
Three Dimensional ◽  
River Mouth ◽  
Stokes Drift ◽  
Radiation Stress ◽  
Fully Nonlinear ◽  
Salt Wedge ◽  
Significant Difference

This paper describes the influence of surface waves on salt-wedge intrusion in terms of radiation stress. Radiation stress may increase salt-wedge intrusion when surface waves propagate up a river. This study thus aims to reveal the effect of radiation stress on the distance of salt-wedge intrusion by using fully nonlinear strongly dispersive internal wave equations and three-dimensional numerical computation model, Fantom3D. Fully nonlinear strongly dispersive internal wave model reveals the possibility that large radiation stress is induced near the river mouth and increases the distance of salt-wedge intrusion. Three-dimensional numerical model also demonstrates that there is a significant difference in the intrusion distance by taking into account radiation stress.

Wave–Current Interaction: A Comparison of Radiation-Stress and Vortex-Force Representations

2007 ◽  
Vol 37 (5) ◽  
pp. 1122-1141 ◽  
Author(s):  
E. M. Lane ◽  
J. M. Restrepo ◽  
J. C. McWilliams
Keyword(s):  
Three Dimensional ◽  
Stokes Drift ◽  
Surface Boundary ◽  
Leading Order ◽  
Radiation Stress ◽  
Infragravity Waves ◽  
Surface Boundary Conditions ◽  
Stress Representation ◽  
Current Interaction ◽  
Interaction Stress

Abstract The vortex-force representation of the wave-averaged effects on currents is compared to the radiation-stress representation in a scaling regime appropriate to coastal and shelf waters. Three-dimensional and vertically integrated expressions for the conservative current equations are obtained in both representations. The vortex-force representation decomposes the main wave-averaged effects into two physically understandable concepts—a vortex force and a Bernoulli head. The vortex force is shown to be the dominant wave-averaged effect on currents. This effect can occur at higher order than the apparent leading order for the radiation-stress representation. Excluding nonconservative effects such as wave breaking, the lowest-order radiation or interaction stress can be completely characterized in terms of wave setup, forcing of long (infragravity) waves, and an Eulerian current whose divergence cancels that of the primary wave Stokes drift. The leading-order, wave-averaged dynamical effects incorporate the vortex force together with material advection by Stokes drift, modified pressure-continuity and kinematic surface boundary conditions, and parameterized representations of wave generation by the wind and breaking near the shoreline.

An analogy between electromagnetic and internal waves

2019 ◽  
Vol 485 (4) ◽  
pp. 428-433
Author(s):  
V. G. Baydulov ◽  
P. A. Lesovskiy
Keyword(s):  
Angular Momentum ◽  
Conservation Laws ◽  
Internal Wave ◽  
Special Relativity ◽  
Internal Waves ◽  
Maxwell Equations ◽  
Wave Equations ◽  
Lagrange Function ◽  
Lorentz Transformations ◽  
Symmetry Transformations

For the symmetry group of internal-wave equations, the mechanical content of invariants and symmetry transformations is determined. The performed comparison makes it possible to construct expressions for analogs of momentum, angular momentum, energy, Lorentz transformations, and other characteristics of special relativity and electro-dynamics. The expressions for the Lagrange function are defined, and the conservation laws are derived. An analogy is drawn both in the case of the absence of sources and currents in the Maxwell equations and in their presence.

Development of Mucoadhesive Buccal Drug Delivery System of Propranolol Hydrochloride Using Aster ericoides Mucilage

2020 ◽  
Vol 10 (2) ◽  
pp. 133-148
Author(s):  
Ankaj Kaundal ◽  
Pravin Kumar ◽  
Rajendra Awasthi ◽  
Giriraj T. Kulkarni
Keyword(s):  
Buccal Cavity ◽  
Three Dimensional ◽  
Hot Water ◽  
Fickian Diffusion ◽  
Aster Ericoides ◽  
Dimensional Network ◽  
Buccal Tablet ◽  
Significant Difference ◽  
Volunteer Group

Aim: The study was aimed to develop mucoadhesive buccal tablets using Aster ericoides leaves mucilage. Background : Mucilages are naturally occurring high-molecular-weight polyuronides, which have been extensively studied for their application in different pharmaceutical dosage forms. Objective: The objective of the present research was to establish the mucilage isolated from the leaves of Aster ericoides as an excipient for the formulation of the mucoadhesive buccal tablet. Method: The mucilage was isolated from the leaves of Aster ericoides by maceration, precipitated with acetone and characterized. Tablets were prepared using wet granulation technique and evaluated for various official tests. Results: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Conclusion: The mucilage was found to be non-toxic on A-431 and Vero cell lines. It was insoluble but swellable in cold and hot water. The results indicate that mucilage can form a three-dimensional network. The pH of the mucilage (6.82 ± 0.13) indicated that it might be non-irritant to the buccal cavity. The mucilage was found to be free from microbes. The release of drug was by Fickian diffusion. The in vivo buccal tablet acceptance was 80%. No significant difference between the diastolic blood pressure of standard and Aster tablets treated volunteer group was recorded. Other: However, to prove the potency of the polymer, in vivo bioavailability studies in human volunteers are needed along with chronic toxicity studies in suitable animal models.

scholarly journals Efficacy evaluation of three-dimensional printing assisted osteotomy guide plate in accurate osteotomy of adolescent cubitus varus deformity

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Yuan-Wei Zhang ◽  
Xin Xiao ◽  
Wen-Cheng Gao ◽  
Yan Xiao ◽  
Su-Li Zhang ◽  
...  
Keyword(s):  
3D Printing ◽  
Blood Loss ◽  
Three Dimensional ◽  
Operation Time ◽  
Varus Deformity ◽  
Conventional Group ◽  
Intraoperative Blood Loss ◽  
Cubitus Varus ◽  
Guide Plate ◽  
Significant Difference

Abstract Background This present study is aimed to retrospectively assess the efficacy of three-dimensional (3D) printing assisted osteotomy guide plate in accurate osteotomy of adolescent cubitus varus deformity. Material and methods Twenty-five patients (15 males and 10 females) with the cubitus varus deformity from June 2014 to December 2017 were included in this study and were enrolled into the conventional group (n = 11) and 3D printing group (n = 14) according to the different surgical approaches. The operation time, intraoperative blood loss, osteotomy degrees, osteotomy end union time, and postoperative complications between the two groups were observed and recorded. Results Compared with the conventional group, the 3D printing group has the advantages of shorter operation time, less intraoperative blood loss, higher rate of excellent correction, and higher rate of the parents’ excellent satisfaction with appearance after deformity correction (P < 0.001, P < 0.001, P = 0.019, P = 0.023). Nevertheless, no significant difference was presented in postoperative carrying angle of the deformed side and total complication rate between the two groups (P = 0.626, P = 0.371). Conclusions The operation assisted by 3D printing osteotomy guide plate to correct the adolescent cubitus varus deformity is feasible and effective, which might be an optional approach to promote the accurate osteotomy and optimize the efficacy.

scholarly journals The Effect of Perioral Scan and Artificial Skin Markers on the Accuracy of Virtual Dentofacial Integration: Stereophotogrammetry Versus Smartphone Three-Dimensional Face-Scanning

2020 ◽  
Vol 18 (1) ◽  
pp. 229
Author(s):  
Hang-Nga Mai ◽  
Du-Hyeong Lee
Keyword(s):  
Three Dimensional ◽  
Laser Scanner ◽  
Statistical Analyses ◽  
Integrated Models ◽  
Image Integration ◽  
Positional Accuracy ◽  
Significant Difference ◽  
Face Scanning ◽  
Scanning Systems ◽  
Dimensional Face

This study evaluated the effects of different matching methods on the accuracy of dentofacial integration in stereophotogrammetry and smartphone face-scanning systems. The integration was done (N = 30) with different matching areas (n = 10), including teeth image only (TO), perioral area without markers (PN) and with markers (PM). The positional accuracy of the integrated models was assessed by measuring the midline linear deviations and incisal line canting between the experimental groups and laser scanner-based reference standards. Kruskal–Wallis and Mann–Whitney U tests were used for statistical analyses (α = 0.05). The PM method exhibited the smallest linear deviations in both systems; while the highest deviations were found in the TO in stereophotogrammetry; and in PN in smartphone. For the incisal line canting; the canting degree was the lowest in the PM method; followed by that in the TO and the PN in both systems. Although stereophotogrammetry generally exhibited higher accuracy than the smartphone; the two systems demonstrated no significant difference when the perioral areas were used for matching. The use of perioral scans with markers enables accurate dentofacial image integration; however; cautions should be given on the accuracy of the perioral image obtained without the use of markers.

scholarly journals Acoustic Cell Patterning in Hydrogel for Three-Dimensional Cell Network Formation

Micromachines ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 3
Author(s):  
Kyo-in Koo ◽  
Andreas Lenshof ◽  
Le Thi Huong ◽  
Thomas Laurell
Keyword(s):  
Network Formation ◽  
Umbilical Vein ◽  
Three Dimensional ◽  
Extrusion Process ◽  
Fibroblast Cells ◽  
Glass Capillary ◽  
Cell Network ◽  
Significant Difference ◽  
The One ◽  
Umbilical Vein Endothelial Cells

In the field of engineered organ and drug development, three-dimensional network-structured tissue has been a long-sought goal. This paper presents a direct hydrogel extrusion process exposed to an ultrasound standing wave that aligns fibroblast cells to form a network structure. The frequency-shifted (2 MHz to 4 MHz) ultrasound actuation of a 400-micrometer square-shaped glass capillary that was continuously perfused by fibroblast cells suspended in sodium alginate generated a hydrogel string, with the fibroblasts aligned in single or quadruple streams. In the transition from the one-cell stream to the four-cell streams, the aligned fibroblast cells were continuously interconnected in the form of a branch and a junction. The ultrasound-exposed fibroblast cells displayed over 95% viability up to day 10 in culture medium without any significant difference from the unexposed fibroblast cells. This acoustofluidic method will be further applied to create a vascularized network by replacing fibroblast cells with human umbilical vein endothelial cells.

scholarly journals Organ motion in linac-based SBRT for glottic cancer

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Annarita Perillo ◽  
Valeria Landoni ◽  
Alessia Farneti ◽  
Giuseppe Sanguineti
Keyword(s):  
Early Stage ◽  
Displacement Vector ◽  
Thyroid Cartilage ◽  
Three Dimensional ◽  
Target Volume ◽  
Glottic Cancer ◽  
Organ Motion ◽  
Delivery Times ◽  
Significant Difference ◽  
Pre Treatment

Abstract Purpose The purpose of this study is to evaluate inter- and intra-fraction organ motion as well as to quantify clinical target volume (CTV) to planning target volume (PTV) margins to be adopted in the stereotactic treatment of early stage glottic cancer. Methods and materials Stereotactic body radiotherapy (SBRT) to 36 Gy in 3 fractions was administered to 23 patients with early glottic cancer T1N0M0. Patients were irradiated with a volumetric intensity modulated arc technique delivered with 6 MV FFF energy. Each patient underwent a pre-treatment cone beam computed tomography (CBCT) to correct the setup based on the thyroid cartilage position. Imaging was repeated if displacement exceeded 2 mm in any direction. CBCT imaging was also performed after each treatment arc as well as at the end of the delivery. Swallowing was allowed only during the beam-off time between arcs. CBCT images were reviewed to evaluate inter- and intra-fraction organ motion. The relationships between selected treatment characteristics, both beam-on and delivery times as well as organ motion were investigated. Results For the population systematic (Ʃ) and random (σ) inter-fraction errors were 0.9, 1.3 and 0.6 mm and 1.1, 1.3 and 0.7 mm in the left-right (X), cranio-caudal (Y) and antero-posterior (Z) directions, respectively. From the analysis of CBCT images acquired after treatment, systematic (Ʃ) and random (σ) intra-fraction errors resulted 0.7, 1.6 and 0.7 mm and 1.0, 1.5 and 0.6 mm in the X, Y and Z directions, respectively. Margins calculated from the intra-fraction errors were 2.4, 5.1 and 2.2 mm in the X, Y and Z directions respectively. A statistically significant difference was found for the displacement in the Z direction between patients irradiated with > 2 arcs versus ≤ 2 arcs, (MW test, p = 0.038). When analyzing mean data from CBCT images for the whole treatment, a significant correlation was found between the time of delivery and the three dimensional displacement vector (r = 0.489, p = 0.055), the displacement in the Y direction (r = 0.553, p = 0.026) and the subsequent margins to be adopted (r = 0.626, p = 0.009). Finally, displacements and the subsequent margins to be adopted in Y direction were significantly greater for treatments with more than 2 arcs (MW test p = 0.037 and p = 0.019, respectively). Conclusions In the setting of controlled swallowing during treatment delivery, intra-fraction motion still needs to be taken into account when planning with estimated CTV to PTV margins of 3, 5 and 3 mm in the X, Y and Z directions, respectively. Selected treatments may require additional margins.

Sign in / Sign up

Export Citation Format

Share Document