scholarly journals Evaluation of Manuka Honey Estrogen Activity Using the MCF-7 Cell Proliferation Assay

2016 ◽  
Vol 10 (3) ◽  
pp. 1-11
Author(s):  
Kathleen Henderson ◽  
Tahrir Aldhirgham ◽  
Poonam Nigam ◽  
Richard Owusu-Apenten
Keyword(s):  
Cell Proliferation ◽  
Proliferation Assay ◽  
Manuka Honey ◽  
Cell Proliferation Assay ◽  
Estrogen Activity ◽  
Mcf 7

scholarly journals Analysis of Estrogenic Activity in Maryland Coastal Bays Using the MCF-7 Cell Proliferation Assay

2021 ◽  
Vol 18 (12) ◽  
pp. 6254
Author(s):  
Rehab Elfadul ◽  
Roman Jesien ◽  
Ahmed Elnabawi ◽  
Paulinus Chigbu ◽  
Ali Ishaque
Keyword(s):  
Cell Proliferation ◽  
Estrogenic Activity ◽  
Landing Site ◽  
Negative Control ◽  
Proliferation Assay ◽  
Negative Effects ◽  
Cell Proliferation Assay ◽  
Coastal Bays ◽  
Maryland Coastal Bays ◽  
Mcf 7

Contaminants of Emerging Concern (CECs) with estrogenic or estrogenic-like activity have been increasingly detected in aquatic environments and have been an issue of global concern due to their potential negative effects on wildlife and human health. This study used the MCF-7 cell proliferation assay (E-Screen) to assess the estrogenic activity profiles in Maryland Coastal Bays (MCBs), a eutrophic system of estuaries impacted by human activities. Estrogenic activity was observed in all study sites tested. Water samples from MCBs increased MCF-7 cell proliferation above the negative control from 2.1-fold at site 8, located in Sinepuxent Bay close to the Ocean City Inlet, to 6.3-fold at site 6, located in Newport Bay. The proliferative effects of the sediment samples over the negative control ranged from 1.9-fold at the Assateague Island National Seashore site to 7.7-fold at the Public Landing site. Moreover, elevated cell proliferation (p < 0.05) was observed when cells were co-exposed with 17ß-Estradiol (E2), while reduction in cell proliferation was observed when cells were co-exposed with the antagonist ICI 182, 780 suggesting that cell proliferative effects were primarily mediated by the estrogen receptor (ER). These results suggest the occurrence of some estrogenic or hormonal-like compounds in the MCBs and are consistent with our previous findings based on vitellogenin analyses.

scholarly journals A Robotic MCF-7:WS8 Cell Proliferation Assay to Detect Agonist and Antagonist Estrogenic Activity

2013 ◽  
Vol 137 (2) ◽  
pp. 335-349 ◽  
Author(s):  
C. Z. Yang ◽  
W. Casey ◽  
M. A. Stoner ◽  
G. J. Kollessery ◽  
A. W. Wong ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Estrogenic Activity ◽  
Proliferation Assay ◽  
Cell Proliferation Assay ◽  
Agonist And Antagonist ◽  
Mcf 7

Screening of Korean edible wild plants for estrogenic activity using MCF-7 cell proliferation assay

2011 ◽  
Vol 20 (3) ◽  
pp. 829-833 ◽  
Author(s):  
Young Min Lee ◽  
Ho Young Jung ◽  
Ji Hyun Bae ◽  
Jin Young Lee ◽  
Hwan Hee Jang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Estrogenic Activity ◽  
Wild Plants ◽  
Proliferation Assay ◽  
Cell Proliferation Assay ◽  
Edible Wild Plants ◽  
Mcf 7

scholarly journals Estimation of Estrogenic and Anti-estrogenic Activities of Some Phthalate Diesters and Monoesters by MCF-7 Cell Proliferation Assay in Vitro

2003 ◽  
Vol 26 (8) ◽  
pp. 1219-1224 ◽  
Author(s):  
Tomoko Okubo ◽  
Toshinari Suzuki ◽  
Yoshiko Yokoyama ◽  
Kazutaka Kano ◽  
Itsu Kano
Keyword(s):  
Cell Proliferation ◽  
Proliferation Assay ◽  
Cell Proliferation Assay ◽  
Mcf 7

Rapid Evaluation ofAntrodia camphorataNatural Products and Derivatives in Tumourigenic Liver Progenitor Cells with a Novel Cell Proliferation Assay

ChemMedChem ◽  
2009 ◽  
Vol 4 (10) ◽  
pp. 1657-1667 ◽  
Author(s):  
Scott G. Stewart ◽  
Louisa A. Ho ◽  
Marta E. Polomska ◽  
Alexander T. Percival ◽  
George C. T. Yeoh
Keyword(s):  
Cell Proliferation ◽  
Progenitor Cells ◽  
Rapid Evaluation ◽  
Proliferation Assay ◽  
Cell Proliferation Assay

Nifuroxazide as JAK2 inhibitor: A binding mode proposal and Hel cell proliferation assay

2021 ◽  
Vol 162 ◽  
pp. 105822
Author(s):  
Marcela Oliveira Legramanti da Costa ◽  
Thais Fernanda Amorim Pavani ◽  
Angélica Nakagawa Lima ◽  
Ana Lígia Scott ◽  
Débora Felicia Vieira Ramos ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Binding Mode ◽  
Proliferation Assay ◽  
Cell Proliferation Assay ◽  
Jak2 Inhibitor
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