scholarly journals NEURO PROTECTIVE POTENTIAL OF ETHANOLIC EXTRACT OF HYPERICUM HOOKERIANUM IN HALOPERIDOL INDUCED SCHIZOPHRENIA IN SWISS ALBINO MICE

2014 ◽  
Vol 5 (6) ◽  
pp. 454-458 ◽  
Author(s):  
Uma Devi Pongiya ◽  
Badarunnisha . ◽  
Yalaga Rama Rao
Author(s):  
Jacob Jesurun RS ◽  
Senthilkumaran Jagadeesh ◽  
Somasundaram Ganesan ◽  
Venugopala Rao K ◽  
Madhavi Eerike

2015 ◽  
Vol 5 (4) ◽  
pp. 85-91 ◽  
Author(s):  
Palaniselvam Kuppusamy ◽  
R.S. David Paul Raj ◽  
Soundharrajan Ilavenil ◽  
Balasubramanian Kaleeswaran ◽  
Natanamurugaraj Govindan ◽  
...  

2021 ◽  
Vol 9 (02) ◽  
pp. 50-55
Author(s):  
Chandrajeet Kumar Yadav ◽  
Poonam Tiwari ◽  
Roshan Mehta ◽  
Amit Kumar Shrivastava ◽  
Anjan Palikhey

INTRODUCTION: Pain has been described by the International Association for the Study of Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Although NSAIDS and OPIOIDS are available for the treatment, still pain (chronic) is major problem. The present study was designed to study the analgesic effect of ethanolic extract of Coriandrum sativum using hot plate method and acetic acid induced writhing method in experimental animals (Swiss albino mice). MATERIAL AND METHODS:The analgesic effect of leaves and seeds of Coriandrum sativum was assessed using hot plate method and acetic acid induced writhing method in Swiss albino mice. The animals were treated with the ethanolic extract of leaves and seeds of Coriandrum sativum orally at two doses of 100, 500 mg/kg body weight after electric heat and acetic acid induced pain in mice. RESULTS: The study showed that ethanolic extract of leaves and seeds of Coriandrum sativum presented significant (p<0.05) and (p<0.05) analgesic activity in mice simultaneously. The data were analyzed by one-way ANOVA followed by Dunette's multiple comparison test. The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got analgesic potential. CONCLUSION: The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got significant analgesic effect.


Author(s):  
Chouhan Vaishali ◽  
Sujane Sandhya ◽  
Bapna Rajendra ◽  
Pyathi Asharani

Anxiety disorder is one of the most common mental ailments exhibited by human. It is characterized by motor tension, sympathetic hyperactivity and apprehension and vigilance syndromes. A part from very few chemical remedies available like benzodiazepine and serotonin modulators, not much treatment options are at hand that safely and effectively alleviate anxiety. The ethanol extract of the fruits of plant Limonia acidissima was evaluated for its anti-anxiety activity in swiss albino mice at dose 200mg/kg and 400mg/kg body weight. Anti-anxiety was assessed by using elevated plus maze (EPM) and light and dark model methods. The ethanolic extract exhibit anxiolytic effect in experimental mice. So it is supports the use of Limonia acidissima as anxiolytic agents. Further investigation should be made to elucidate the active constituent of responsible for the activity.


2017 ◽  
Vol 10 (1) ◽  
pp. 427-433 ◽  
Author(s):  
Shashikumara Shashikumara ◽  
Prathima. C ◽  
Mohammed Sibgatullah

Sign in / Sign up

Export Citation Format

Share Document