scholarly journals Plasma fatty acid composition and eicosapentaenoic acid (EPA)/arachidonic acid (AA) ratio in healthy people and patients with coronary artery disease living in local urban area surrounding farm villages

2013 ◽  
Vol 19 (3) ◽  
pp. 209-215
Author(s):  
Kentarou Matsumura
Keyword(s):  
Coronary Artery Disease ◽  
Arachidonic Acid ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Eicosapentaenoic Acid ◽  
Urban Area ◽  
Plasma Fatty Acid ◽  
Plasma Fatty Acid Composition ◽  
Artery Disease

scholarly journals Relationships between Plasma Fatty Acid Composition and Coronary Artery Disease

2011 ◽  
Vol 18 (2) ◽  
pp. 99-107 ◽  
Author(s):  
Hiroshige Itakura ◽  
Mitsuhiro Yokoyama ◽  
Masunori Matsuzaki ◽  
Yasushi Saito ◽  
Hideki Origasa ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Acid Composition ◽  
Plasma Fatty Acid ◽  
Plasma Fatty Acid Composition ◽  
Artery Disease

Fatty acid composition of HDL phospholipids and coronary artery disease

2009 ◽  
Vol 3 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Mohammad Noori ◽  
Masoud Darabi ◽  
Ali Rahimipour ◽  
Mohammad Rahbani ◽  
Naser Aslan Abadi ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Acid Composition ◽  
Artery Disease

Abstract 13973: Circulating Eicosapentaenoic Acid to Oleic Acid Ratio and Risk for Cardiovascular Events in Patients With Coronary Artery Disease; Sub-analysis of SHINANO Registry

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Hirofumi Hioki ◽  
Takashi Miura ◽  
Yusuke Miyashita ◽  
Souichirou Ebisawa ◽  
Hirohiko Motoki ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Oleic Acid ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Eicosapentaenoic Acid ◽  
Roc Curve ◽  
Cardiovascular Events ◽  
Pufa Ratio ◽  
Coronary Syndrome ◽  
Artery Disease

Background: Until now, Omega-3/Omega-6 polyunsaturated fatty acid (PUFA) ratio, particularly in ratio of eicosapentaenoic acid (EPA) to arachnidonic acid (AA), has been reported to associate with the incidence of cardiovascular events. However, the clinical impact of monounsaturated fatty acid (MUFA) on cardiovascular events has not been well understood. Objective: In this study, we evaluate whether ratio of MUFA to PUFA, especially EPA/Oleic acid (OA), could predict clinical outcome in patients with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). Methods: SHINANO registry was prospective, observational, multicenter cohort study, enrolling 1,923 consecutive patients with CAD. From this registry, we identified 182 patients who measured fatty acid on admission. We stratified according to median of EPA/OA ratio. The primary endpoint was net adverse clinical events (NACE) including cardiac death, nonfatal myocardial infarction, ischemic stroke, PCI for ACS, heart failure, and major bleeding (Bleeding Academic Research Consortium II-IV) for 1-years. Results: Mean age was 72±10 years, 24% female, and 27% was acute coronary syndrome. One-years follow-up was completed in 181 patients (99.5%). Cumulative incidence of NACE was 22 cases. In Kaplan-Meier analysis, incidence of NACE was significantly higher in patients with EPA/OA of 0.03 to 0.12 compared to 0.13 to 0.54 (16.6% vs. 6.6%, Log-rank p=0.025). After adjusting for the calculated propensity score for EPA/OA ≥ 0.13 or not, EPA/OA ≥ 0.13 was remained an independent predictor of NACE (hazard ratio, 0.36; 95% confidence interval [CI], 0.14-0.96; p-value 0.042). The ROC curve of EPA/OA for NACE demonstrated that the area under the ROC curve (ACU) was 0.73 (95% CI; 0.61-0.85). Conclusions: This study firstly demonstrated that the patients with high EPA/OA ratio would have low incidence of NACE in patients with CAD who underwent PCI.

scholarly journals Association of plasma fatty acid alteration with the severity of coronary artery disease lesions in Tunisian patients

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Samia Hadj Ahmed ◽  
Nadia Kaoubaa ◽  
Wafa Kharroubi ◽  
Amira Zarrouk ◽  
Mohamed Fadhel Najjar ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Fatty Acid ◽  
Coronary Artery ◽  
Plasma Fatty Acid ◽  
Tunisian Patients ◽  
Artery Disease ◽  
Acid Alteration

Eicosapentaenoic Acid Combined with Optimal Statin Therapy Improves Endothelial Dysfunction in Patients with Coronary Artery Disease

2013 ◽  
Vol 28 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Kentaro Toyama ◽  
Toshihiko Nishioka ◽  
Ami Isshiki ◽  
Toshiyuki Ando ◽  
Yoshiro Inoue ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Endothelial Dysfunction ◽  
Eicosapentaenoic Acid ◽  
Statin Therapy ◽  
Artery Disease
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