scholarly journals Tandem Thoracic Spinal Cord Lesions of Differing Pathologies: Concurrent Metastatic Lung Adenocarcinoma Lesion in Close Proximity to a Intradural Meningioma

Cureus ◽  
2020 ◽  
Author(s):  
Shawn S Rai ◽  
Carlos Goulart ◽  
Ziya Gokaslan ◽  
Michael Galgano
Keyword(s):  
Spinal Cord ◽  
Lung Adenocarcinoma ◽  
Spinal Cord Lesions ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Close Proximity ◽  
Metastatic Lung

scholarly journals Central neuropathic pain in MS is due to distinct thoracic spinal cord lesions

2014 ◽  
Vol 1 (8) ◽  
pp. 554-561 ◽  
Author(s):  
Darin T. Okuda ◽  
Kara Melmed ◽  
Takashi Matsuwaki ◽  
Anders Blomqvist ◽  
Arthur D. Bud Craig
Keyword(s):  
Spinal Cord ◽  
Neuropathic Pain ◽  
Spinal Cord Lesions ◽  
Thoracic Spinal Cord ◽  
Central Neuropathic Pain ◽  
Thoracic Spinal

scholarly journals Acute Polyradiculomyelitis With Spinal Cord Gray Matter Lesions: A Report of Two Cases

2021 ◽  
Vol 12 ◽  
Author(s):  
Charidimos Tsagkas ◽  
Maria Janina Wendebourg ◽  
Matthias Mehling ◽  
Johannes Lorscheider ◽  
Philippe Lyrer ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Gray Matter ◽  
Case Reports ◽  
Motor Impairment ◽  
Bowel Dysfunction ◽  
Motor Deficits ◽  
Spinal Cord Lesions ◽  
Rare Presentation ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal

Objective: Inflammatory polyradiculomyelitis belongs to a rare group of immune-mediated diseases affecting both the central and peripheral nervous system. We aimed to describe an unusual presentation of acute polyradiculomyelitis with marked spinal cord lesions restricted to the gray matter.Methods: Thorough examination of two case reports including clinical, MRI, serologic, electrophysiologic and CSF examinations as well as short-term follow-up.Results: We present two adult patients with acute polyradiculomyelitis and unusual spinal cord lesions restricted to the gray matter on MRI. The clinical presentation, serologic, electrophysiologic and CSF features of the two patients varied, whereas both patients demonstrated severe, asymmetrical, predominantly distal, motor deficits of the lower extremities as well as bladder and bowel dysfunction. Both patients only partially responded to anti-inflammatory treatment. Severe motor impairment and bladder dysfunction persisted even months after symptom onset.Conclusions: To our best of knowledge, these are the first reports of acute polyradiculomyelitis with distinct involvement of the lower thoracic spinal cord gray matter. Currently, it remains unclear whether gray matter lesions reflect a separate pathophysiologic mechanism or an exceedingly rare presentation of spinal cord involvement in acute polyradiculomyelitis.

scholarly journals Thoracic spinal cord lesions are influenced by the degree of cervical spine involvement in multiple sclerosis

Spinal Cord ◽  
2015 ◽  
Vol 53 (7) ◽  
pp. 520-525 ◽  
Author(s):  
L H Hua ◽  
S L Donlon ◽  
M J Sobhanian ◽  
S M Portner ◽  
D T Okuda
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Cervical Spine ◽  
Spinal Cord Lesions ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal

Cardiovascular responses to arm static exercise in men with thoracic spinal cord lesions

2011 ◽  
Vol 112 (2) ◽  
pp. 661-666 ◽  
Author(s):  
Keiko Sakamoto ◽  
Takeshi Nakamura ◽  
Yasunori Umemoto ◽  
Yumi Koike ◽  
Yusuke Sasaki ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Cardiovascular Responses ◽  
Static Exercise ◽  
Spinal Cord Lesions ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal

Spontaneous Herniation of the Thoracic Spinal Cord: A Case Report

2001 ◽  
Vol 45 (4) ◽  
pp. 353 ◽  
Author(s):  
Sung Chan Jin ◽  
Seoung Ro Lee ◽  
Dong Woo Park ◽  
Kyung Bin Joo
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Spontaneous Herniation

Lipomeningocele associated with diplomyelia in a dog

2018 ◽  
Vol 46 (05) ◽  
pp. 323-329 ◽  
Author(s):  
Nele Ondreka ◽  
Sara Malberg ◽  
Emma Laws ◽  
Martin Schmidt ◽  
Sabine Schulze
Keyword(s):  
Spinal Cord ◽  
Neurological Status ◽  
Split Cord Malformation ◽  
Lumbar Spinal Cord ◽  
Histopathological Diagnosis ◽  
Type I ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Subcutaneous Mass ◽  
Lumbar Spinal

SummaryA 2-year-old male neutered mixed breed dog with a body weight of 30 kg was presented for evaluation of a soft subcutaneous mass on the dorsal midline at the level of the caudal thoracic spine. A further clinical sign was intermittent pain on palpation of the area of the subcutaneous mass. The owner also described a prolonged phase of urination with repeated interruption and re-initiation of voiding. The findings of the neurological examination were consistent with a lesion localization between the 3rd thoracic and 3rd lumbar spinal cord segments. Magnetic resonance imaging revealed a spina bifida with a lipomeningocele and diplomyelia (split cord malformation type I) at the level of thoracic vertebra 11 and 12 and secondary syringomyelia above the aforementioned defects in the caudal thoracic spinal cord. Surgical resection of the lipomeningocele via a hemilaminectomy was performed. After initial deterioration of the neurological status postsurgery with paraplegia and absent deep pain sensation the dog improved within 2 weeks to non-ambulatory paraparesis with voluntary urination. Six weeks postoperatively the dog was ambulatory, according to the owner. Two years after surgery the owner recorded that the dog showed a normal gait, a normal urination and no pain. Histopathological diagnosis of the biopsied material revealed a lipomeningocele which confirmed the radiological diagnosis.

scholarly journals The Histopathology of Severe Graded Compression in Lower Thoracic Spinal Cord Segment of Rat, Evaluated at Late Post-injury Phase

2021 ◽  
Author(s):  
Fedorova Jana ◽  
Kellerova Erika ◽  
Bimbova Katarina ◽  
Pavel Jaroslav
Keyword(s):  
Spinal Cord ◽  
Spontaneous Recovery ◽  
Traumatic Injury ◽  
Blue Dye ◽  
Post Injury ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Severe Traumatic Injury ◽  
Spinal Cord Segment ◽  
Cord Injury

AbstractSpontaneous recovery of lost motor functions is relative fast in rodent models after inducing a very mild/moderate spinal cord injury (SCI), and this may complicate a reliable evaluation of the effectiveness of potential therapy. Therefore, a severe graded (30 g, 40 g and 50 g) weight-compression SCI at the Th9 spinal segment, involving an acute mechanical impact followed by 15 min of persistent compression, was studied in adult female Wistar rats. Functional parameters, such as spontaneous recovery of motor hind limb and bladder emptying function, and the presence of hematuria were evaluated within 28 days of the post-traumatic period. The disruption of the blood-spinal cord barrier, measured by extravasated Evans Blue dye, was examined 24 h after the SCI, when maximum permeability occurs. At the end of the survival period, the degradation of gray and white matter associated with the formation of cystic cavities, and quantitative changes of glial structural proteins, such as GFAP, and integral components of axonal architecture, such as neurofilaments and myelin basic protein, were evaluated in the lesioned area of the spinal cord. Based on these functional and histological parameters, and taking the animal’s welfare into account, the 40 g weight can be considered as an upper limit for severe traumatic injury in this compression model.

Superficial siderosis due to dural defect with thoracic spinal cord herniation

2012 ◽  
Vol 312 (1-2) ◽  
pp. 170-172 ◽  
Author(s):  
Giorgio B. Boncoraglio ◽  
Elena Ballabio ◽  
Alessandra Erbetta ◽  
Francesco Prada ◽  
Mario Savoiardo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Superficial Siderosis ◽  
Dural Defect ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal ◽  
Spinal Cord Herniation
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