scholarly journals Serum Uric Acid – Risk Factor for Acute Ischemic Stroke and Poor Outcomes

Cureus ◽  
2019 ◽  
Author(s):  
Muhammad Ali Tariq ◽  
Sohaib A Shamim ◽  
Kiran F Rana ◽  
Aisha Saeed ◽  
Bilal Haider Malik
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid ◽  
Poor Outcomes

scholarly journals Study of Serum Uric Acid Level as an Independent Risk Factor in Acute Ischemic Stroke

2020 ◽  
Vol 7 (9) ◽  
pp. 442-445
Author(s):  
Chandrashekhar K ◽  
Mohammed Anwar Hussain ◽  
Ishwar S. Hasabi ◽  
Suryakanth Suryakanth ◽  
Chethan K. Ganteppanavar
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Independent Risk Factor ◽  
Serum Uric Acid Level

Serum Uric Acid Levels and Outcomes After Acute Ischemic Stroke

2015 ◽  
Vol 53 (3) ◽  
pp. 1753-1759 ◽  
Author(s):  
Zhongchao Wang ◽  
Yanlin Lin ◽  
Yuxiu Liu ◽  
Ying Chen ◽  
Bin Wang ◽  
...  
Keyword(s):  
Uric Acid ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid

Lack of association between serum uric acid levels and outcome in acute ischemic stroke

2012 ◽  
Vol 319 (1-2) ◽  
pp. 51-55 ◽  
Author(s):  
Irene Miedema ◽  
Maarten Uyttenboogaart ◽  
Marcus Koch ◽  
Berry Kremer ◽  
Jacques de Keyser ◽  
...  
Keyword(s):  
Uric Acid ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid

scholarly journals Association between serum uric acid and carotid disease in patients with atherosclerotic acute ischemic stroke

Vascular ◽  
2018 ◽  
Vol 27 (1) ◽  
pp. 19-26 ◽  
Author(s):  
José Carlos Arévalo-Lorido ◽  
Juana Carretero-Gómez ◽  
Nicolás Roberto Robles Pérez-Monteoliva
Keyword(s):  
Uric Acid ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Serum Uric Acid ◽  
Pearson Correlation ◽  
Vascular Wall ◽  
Carotid Disease ◽  
Cross Sectional ◽  
Stroke Registry ◽  
Media Thickness

Aim The role of serum uric acid in ischemic stroke is controversial. On the one hand, it has a role as neuroprotectant in acute phase, but on the other hand, it may promote atherosclerosis in carotid arteries. Our aim is to investigate the association of serum uric acid levels at admission of acute ischemic stroke patients with carotid disease. Methods Cross-sectional study of patients admitted due to acute ischemic stroke. Clinical and laboratory variables were recorded. The carotid disease was defined based on the findings of carotid echography intima to media thickness and stenosis. Patients were grouped according to these findings. Robust statistical methods were applied into analysis. Results A total of 245 patients were recruited through a stroke registry. Their values of serum uric acid were related to both carotid intima to media thickness and stenosis showing a positive relationship between serum uric acid levels and intima to media thickness by Pearson correlation ( p < 0.05). Similarly, after adjusting for all potential confounders, eGFR, glucose, age and serum uric acid levels, (OR 1.26 (95% CI 1.04 −1.52, p¼0.01), were identified as independent predictors for having a intima to media thickness ≥1 mm. Similarly, by grouping patients in tertiles of the serum uric acid distribution, we found a predominantly greater carotid disease in the tertile with the highest levels of serum uric acid ( p < 0.005). Conclusion Our study supports the hypotheses that serum uric acid levels have different roles in the case of ischemic stroke. Its effects on the vascular wall contribute to the development of atherosclerosis and carotid disease.

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