scholarly journals Tolvaptan-induced Liver Injury: Who is at Risk? A Case Report and Literature Review

Cureus ◽  
2019 ◽  
Author(s):  
Muhammad Y Khan ◽  
Muhammad Shabbir Rawala ◽  
Maryam Siddiqui ◽  
Waqas Abid ◽  
Aysha Aslam
Author(s):  
Alessia Maria Calabrese ◽  
Valeria Calsolaro ◽  
Riccardo Franchi ◽  
Sara Rogani ◽  
Daniela Guarino ◽  
...  

2019 ◽  
Vol 18 (3) ◽  
pp. 192-196
Author(s):  
Maria Panetta ◽  
◽  
Alex Brightmore ◽  
W Stephen Waring ◽  
◽  
...  

Chloroform is a recognised cause of acute liver injury, although now rarely encountered in clinical practice. We present a case of inhalational chloroform self-poisoning in a 47-year-old man that presented to hospital initially with reduced conscious level and later developed acute liver injury that was treated with intravenous acetylcysteine. This paper reviews the existing literature and presents a summary of the mechanisms of chloroform hepatotoxicity. Published cases show that there is a characteristic delay of 24 to 48 hours between chloroform exposure and elevation of liver transaminase activity. Therefore, clinicians need to provide an appropriate duration of monitoring in order to detect the occurrence of this important toxic effect.


2017 ◽  
Vol 41 (4) ◽  
pp. e39-e42 ◽  
Author(s):  
Lucia Parlati ◽  
Cosmin Sebastian Voican ◽  
Katy Perlemuter ◽  
Gabriel Perlemuter

Author(s):  
Vijay Gayam ◽  
Amrendra Kumar Mandal ◽  
Mazin Khalid ◽  
Binav Shrestha ◽  
Pavani Garlapati ◽  
...  

2003 ◽  
Vol 37 (3) ◽  
pp. 395-397 ◽  
Author(s):  
Seyfettin Köklü ◽  
Osman Yüksel ◽  
Levent Filik ◽  
Oğuz Üsküdar ◽  
Kadri Altundağ ◽  
...  

OBJECTIVE: To present a single case of ampicillin-induced recurrent cholestasis and a literature review. CASE SUMMARY: A 23-year-old man was hospitalized due to recurrent and self-limited cholestatic symptoms. He had used ampicillin before each cholestatic attack. He became well clinically and biochemically each time after cessation of the drug. One year after his recovery and discontinuance of ampicillin, the patient has had no recurrence of cholestasis. An objective causality assessment revealed that the adverse drug reaction was probable. DISCUSSION: Ampicillin-related hepatotoxicity is very rare, with injury being mainly hepatocellular. To our knowledge, there is only 1 case report in the literature referring to chronic cholestatic-type hepatotoxicity related to ampicillin. CONCLUSIONS: Ampicillin, which is one of the most widely used antibiotics, may cause recurrent cholestatic hepatitis. Clinicians should be aware of this adverse effect, and it should be kept in mind during diagnostic workup of liver injury.


Injury ◽  
2012 ◽  
Vol 43 (1) ◽  
pp. 119-122 ◽  
Author(s):  
Melissa M. Beitner ◽  
Nancy Suh ◽  
Richard Dowling ◽  
Julie A. Miller

2013 ◽  
Vol 2 (2) ◽  
pp. 81-83
Author(s):  
Dan-ying Cheng ◽  
Xiao-mei Wang ◽  
Wei-ni Ou ◽  
Hui-chun Xing

Abstract Drug-induced liver injury (DILI) is defined as injury to the liver caused by exposure to a drug or some drugs. The number of cases suffering from DILI has been increasing. There are few clinical features specifically associated with DILI. The recognition and diagnosis of DILI is difficult. In this report, we described a DILI case caused by herbal remedies.


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