scholarly journals Delayed onset of liver injury after intentional chloroform overdose: a case report and literature review

2019 ◽  
Vol 18 (3) ◽  
pp. 192-196
Author(s):  
Maria Panetta ◽  
◽  
Alex Brightmore ◽  
W Stephen Waring ◽  
◽  
...  

Chloroform is a recognised cause of acute liver injury, although now rarely encountered in clinical practice. We present a case of inhalational chloroform self-poisoning in a 47-year-old man that presented to hospital initially with reduced conscious level and later developed acute liver injury that was treated with intravenous acetylcysteine. This paper reviews the existing literature and presents a summary of the mechanisms of chloroform hepatotoxicity. Published cases show that there is a characteristic delay of 24 to 48 hours between chloroform exposure and elevation of liver transaminase activity. Therefore, clinicians need to provide an appropriate duration of monitoring in order to detect the occurrence of this important toxic effect.

Author(s):  
Alessia Maria Calabrese ◽  
Valeria Calsolaro ◽  
Riccardo Franchi ◽  
Sara Rogani ◽  
Daniela Guarino ◽  
...  

2017 ◽  
Vol 41 (4) ◽  
pp. e39-e42 ◽  
Author(s):  
Lucia Parlati ◽  
Cosmin Sebastian Voican ◽  
Katy Perlemuter ◽  
Gabriel Perlemuter

Author(s):  
Vijay Gayam ◽  
Amrendra Kumar Mandal ◽  
Mazin Khalid ◽  
Binav Shrestha ◽  
Pavani Garlapati ◽  
...  

2018 ◽  
Vol 154 (6) ◽  
pp. S-1205
Author(s):  
Muhammad Baraa Hammami ◽  
Mohammed Eyad Y. Yaseen Alsabbagh

2004 ◽  
Vol 444 (1) ◽  
pp. 87-89 ◽  
Author(s):  
Annette Zimpfer ◽  
Albert Propst ◽  
Gregor Mikuz ◽  
Wolfgang Vogel ◽  
Luigi Terracciano ◽  
...  

2009 ◽  
Vol 57 (2) ◽  
pp. 221 ◽  
Author(s):  
Jong Taek Park ◽  
Young Bok Lee ◽  
Jong Soo Kim ◽  
Hoon Ryu ◽  
Hyun Kyo Lim

Cureus ◽  
2019 ◽  
Author(s):  
Muhammad Y Khan ◽  
Muhammad Shabbir Rawala ◽  
Maryam Siddiqui ◽  
Waqas Abid ◽  
Aysha Aslam

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 319
Author(s):  
Paul Patiniott ◽  
Matheesha Herath ◽  
Peter Riddell

Background: Carpal tunnel syndrome (CTS) is a condition seen commonly in clinical practice; high-flow arteriovenous malformations (AVM) can be a rare but important cause. Case Report: We discuss a case of a patient who had developed left CTS in the fifth decade of life as the result of a progressively enlarging congenital peripheral AVM affecting his left upper limb. This case illustrates the clinical challenges encountered in the surgical and interventional management of this complex issue. Discussion:High-flow AVMs affecting the extremities may be comprised of a convoluted network of vessels in high-flow, low-resistance systems that often recur despite intervention. Conclusion: Peripheral AVM affecting the hand can be a rare and therapeutically challenging cause of carpal tunnel syndrome that warrants multidisciplinary team discussion.


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