scholarly journals Consanguinity and Diabetes in Saudi Population: A Case-Control Study

Cureus ◽  
2021 ◽  
Author(s):  
Saad H Alzahrani ◽  
Nawaf M Alzahrani ◽  
Fahad S Al jabir ◽  
Mohammed K Alsharef ◽  
Shawana Zaheer ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Saudi Population ◽  
Control Study

scholarly journals Risk factors of colorectal cancer among Saudi Population: Case-control study

2020 ◽  
Vol 9 (9) ◽  
pp. 5035
Author(s):  
RishiK Bharti ◽  
MansourZ Alqahtani ◽  
AshryG Mohammed ◽  
AwadS Alsamghan ◽  
AbdullahA Alsharm ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Saudi Population ◽  
Control Study

Genetic Variation in IL-6 and TNF-α Genes with Risk of Breast Cancer in a Saudi Population-based Case-Control Study

2012 ◽  
Vol 18 (4) ◽  
pp. 383-385 ◽  
Author(s):  
Ali A. Alshatwi ◽  
Tarique N. Hasan ◽  
Gowhar Shafi ◽  
Adulaziz. A. Alsaif ◽  
Abdulrahman A. Aldiab ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Genetic Variation ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Saudi Population ◽  
Tnf Α ◽  
Control Study

Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population

2017 ◽  
Vol 47 (3) ◽  
pp. 229-240 ◽  
Author(s):  
Gamal Allam ◽  
Amre Nasr ◽  
Iman M. Talaat ◽  
Abdelaziz S. A. Abuelsaad ◽  
Ali M. Bakheit ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Saudi Population ◽  
Cytokine Genes ◽  
Control Study

scholarly journals Role of Apolipoprotein E gene polymorphism in the risk of familial hypercholesterolemia: a case-control study

2018 ◽  
Vol 65 (3) ◽  
Author(s):  
Turky H Almigbal ◽  
Mohammed Ali Batais ◽  
Rana M Hasanato ◽  
Fawaziah Khalaf Alharbi ◽  
Imran Ali Khan ◽  
...  
Keyword(s):  
Apolipoprotein E ◽  
Familial Hypercholesterolemia ◽  
Case Control Study ◽  
Case Control ◽  
Lipid Profiles ◽  
Apoe Gene ◽  
Taqman Assay ◽  
Saudi Population ◽  
Elevated Cholesterol ◽  
Control Study

Familial Hypercholesterolemia (FH) is characterized by elevated cholesterol; this is based on biochemical, clinical, and genetic studies and FH disease, which was documented even with limited mutations. Earlier studies were associated with Apolipoprotein E (ApoE) in variable diseases. The current study aims to investigate the genetic association between FH disease and ApoE gene (rs429358 and rs7412) in the Saudi population. This study has been carried out as a case-control and is a hospital-based study in Saudi Arabia. Two hundred and four subjects were recruited as FH participants (n=104) and the others as controls (n=100). Common polymorphisms (rs429358 and rs7412) were selected from the ApoE gene and we then performed the genotyping as the TaqMan assay. Moreover, the ApoE risk allele E4 is significantly associated in FH cases and controls (OR-2.24 (95%CI: 1.06-4.70); p=0.02). Lipid profile parameters were significantly associated (p<0.05); however, a combination of ApoE alleles and lipid profiles could not find a correlation (p>0.05). The FH case-control study was associated with the E4 allele in the Saudi population. The risk of allele E4 which is a reliable marker for lipid profiles, but did not correlate with ApoE alleles. 

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