scholarly journals Clinical and Laboratory Diagnostic Features of Kyasanur Forest Disease: A Study From Wayanad, South India

Cureus ◽  
2021 ◽  
Author(s):  
Vineeth Gladson ◽  
Hisham Moosan ◽  
Sheela Mathew ◽  
Dineesh P
Keyword(s):  
South India ◽  
Diagnostic Features ◽  
Forest Disease ◽  
Kyasanur Forest Disease

scholarly journals Coverage and Effectiveness of Kyasanur Forest Disease (KFD) Vaccine in Karnataka, South India, 2005–10

2013 ◽  
Vol 7 (1) ◽  
pp. e2025 ◽  
Author(s):  
Gudadappa S. Kasabi ◽  
Manoj V. Murhekar ◽  
Vijay K. Sandhya ◽  
Ramappa Raghunandan ◽  
Shivani K. Kiran ◽  
...  
Keyword(s):  
South India ◽  
Forest Disease ◽  
Kyasanur Forest Disease

A guide to the identification of all stages of the Haemaphysalis ticks of South India

1964 ◽  
Vol 55 (2) ◽  
pp. 249-270 ◽  
Author(s):  
H. Trapido ◽  
M. G. R. Varma ◽  
P. K. Rajagopalan ◽  
K. R. P. Singh ◽  
M. J. Rebello ◽  
...  
Keyword(s):  
Natural History ◽  
South India ◽  
Forest Disease ◽  
Mysore State ◽  
History Of ◽  
Kyasanur Forest Disease

Investigations of the natural history of the virus of Kyasanur Forest disease since its discovery during 1957 in Shimoga District, Mysore State, south India have concentrated much attention on ticks of the genus Haemaphysalis in the region, as virus has repeatedly been isolated from them.Keys are provided for larvae, nymphs and adults of both sexes of the 14 species of Haemaphysalis that have been taken in the area, with supplementary comments on six other species of the genus recorded, or likely to occur, elsewhere in south India. Illustrations are given showing the characters of the larvae and nymphs that are used in the keys.

scholarly journals Low mammalian species richness is associated with Kyasanur forest disease outbreak risk in deforested landscapes in the Western Ghats, India

One Health ◽  
2021 ◽  
pp. 100299
Author(s):  
Michael G. Walsh ◽  
Rashmi Bhat ◽  
Venkatesh Nagarajan-Radha ◽  
Prakash Narayanan ◽  
Navya Vyas ◽  
...  
Keyword(s):  
Species Richness ◽  
Western Ghats ◽  
Mammalian Species ◽  
Disease Outbreak ◽  
Forest Disease ◽  
Kyasanur Forest Disease ◽  
The Western Ghats

scholarly journals In-silico design of envelope based multi-epitope vaccine candidate against Kyasanur forest disease virus

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sathishkumar Arumugam ◽  
Prasad Varamballi
Keyword(s):  
Disease Virus ◽  
In Silico ◽  
Hemorrhagic Fever ◽  
Epitope Vaccine ◽  
Epitope Region ◽  
Vaccine Candidates ◽  
Forest Disease ◽  
In Silico Design ◽  
Antigenic Properties ◽  
Kyasanur Forest Disease

AbstractKyasanur forest disease virus (KFDV) causing tick-borne hemorrhagic fever which was earlier endemic to western Ghats, southern India, it is now encroaching into new geographic regions, but there is no approved medicine or effective vaccine against this deadly disease. In this study, we did in-silico design of multi-epitope subunit vaccine for KFDV. B-cell and T-cell epitopes were predicted from conserved regions of KFDV envelope protein and two vaccine candidates (VC1 and VC2) were constructed, those were found to be non-allergic and possess good antigenic properties, also gives cross-protection against Alkhurma hemorrhagic fever virus. The 3D structures of vaccine candidates were built and validated. Docking analysis of vaccine candidates with toll-like receptor-2 (TLR-2) by Cluspro and PatchDock revealed strong affinity between VC1 and TLR2. Ligplot tool was identified the intermolecular hydrogen bonds between vaccine candidates and TLR-2, iMOD server confirmed the stability of the docking complexes. JCAT sever ensured cloning efficiency of both vaccine constructs and in-silico cloning into pET30a (+) vector by SnapGene showed successful translation of epitope region. IMMSIM server was identified increased immunological responses. Finally, multi-epitope vaccine candidates were designed and validated their efficiency, it may pave the way for up-coming vaccine and diagnostic kit development.

scholarly journals Isolation of Kyasanur Forest Disease Virus from Febrile Patient, Yunnan, China

2009 ◽  
Vol 15 (2) ◽  
pp. 326-328 ◽  
Author(s):  
Jinglin Wang ◽  
Hailin Zhang ◽  
Shihong Fu ◽  
Huanyu Wang ◽  
Daxin Ni ◽  
...  
Keyword(s):  
Disease Virus ◽  
Febrile Patient ◽  
Forest Disease ◽  
Kyasanur Forest Disease
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