scholarly journals Epidemiology, Pathogenesis, and Control of a Tick-Borne Disease- Kyasanur Forest Disease: Current Status and Future Directions

Author(s):  
Syed Z. Shah ◽  
Basit Jabbar ◽  
Nadeem Ahmed ◽  
Anum Rehman ◽  
Hira Nasir ◽  
...  
Author(s):  
Michael Nguyen-Truong ◽  
Peiman Hematti ◽  
Zhijie Wang

Mesenchymal stromal cells (MSCs) have been studied for nearly two decades as a therapy for myocardial restoration. An emerging direction to repair myocardium is through their paracrine function, which includes the utilization of MSC-derived conditioned medium or extracellular vesicles. In this review, we go over the unique characteristics of MSCs that make it suitable for 'off-the-shelf', cell-free regenerative therapy, current MSC-derived cell-free approaches including their advantages and disadvantages, and the known mechanisms of action of the paracrine effect of MSCs. With a summary of the clinical trials and preclinical studies of MSC-derived cell-free therapy, we classify the aforementioned mechanisms into angiogenesis, immunomodulation, collagen regulation, anti-apoptosis, and anti-oxidation. Particularly, we discuss on ways researchers have worked towards enhancing these desired properties to improve the therapeutic outcomes and the investigation of mechanobiology involved in MSC paracrine function. Lastly, we bring up the remaining challenges in this arising field and suggestions for future directions to improve our understanding and control over the potential of MSC paracrine function for myocardial restoration.


2016 ◽  
Vol 17 (8) ◽  
pp. 755-762 ◽  
Author(s):  
Xu Zhou ◽  
Renhe Liu ◽  
Shuo Qin ◽  
Ruilian Yu ◽  
Yao Fu

2020 ◽  
Vol 14 (1) ◽  
pp. 12-28
Author(s):  
Jingang Jiang ◽  
Yihao Chen ◽  
Xuefeng Ma ◽  
Yongde Zhang ◽  
Zhiyuan Huang ◽  
...  

Background: Portable life support system is used in the battlefield, disaster and in other special circumstances such as in space exploration, and underground survey to give the wounded a life support. The most dangerous period for the injured is the first hour after an injury, which is a crucial time for treatment. If the patient's vital signs were stabilized, more than 40% of the injured could be saved. The staff can efficiently complete the task if they get effective and stable vital signs during the operation. Therefore, in order to reduce the risk of disaster and battlefield mortality to improve operational safety and efficiency, it is necessary to study the portable life support system. Objective: The study aimed to provide an overview of recent portable life support system and its characteristics and design. Methods: This paper introduces the patents and products related to a portable life support system, and its characteristics and application. Results: This paper summarizes five kinds of portable life support systems which are box type, stretcher type, bed type, backpack type and mobile type. Moreover, the characteristics of different portable life support systems are analyzed. The paper expounds the problems of different types of portable life support systems and puts forward improvement methods to solve the problems. Finally, the paper points out the future development of the system. Conclusion: Portable life support system plays an increasingly important role in health care. In terms of the structure, function and control, further development and improvements are needed, along with the research on portable life support system.


Author(s):  
Maureen L. Whittal ◽  
Melisa Robichaud

The cornerstone of cognitive treatment (CT) for OCD is based upon the knowledge that unwanted intrusions are essentially a universal experience. As such, it is not the presence of the intrusion that is problematic but rather the associated meaning or interpretation. Treatment is flexible, depending upon the nature of the appraisals and beliefs, but can include strategies focused on inflated responsibility and overestimation of threat, importance and control of thoughts, and the need for perfectionism and certainty. The role of concealment and the relationship to personal values are important maintaining and etiological factors. The short-term and long-term treatment outcome is reviewed, along with predictors of treatment response and mechanisms of action, and the chapter concludes with future directions regarding CT for OCD.


2020 ◽  
Vol 11 ◽  
Author(s):  
Nathaniel Edward Bennett Saidu ◽  
Chiara Bonini ◽  
Anne Dickinson ◽  
Magdalena Grce ◽  
Marit Inngjerdingen ◽  
...  

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Adele Brunetti ◽  
Francesca Macedonio ◽  
Giuseppe Barbieri ◽  
Enrico Drioli

Abstract The recent roadmap of SPIRE initiative includes the development of “new separation, extraction and pre-treatment technologies” as one of the “key actions” for boosting sustainability, enhancing the availability and quality of existing resources. Membrane condenser is an innovative technology that was recently investigated for the recovery of water vapor for waste gaseous streams, such as flue gas, biogas, cooling tower plumes, etc. Recently, it has been also proposed as pre-treatment unit for the reduction and control of contaminants in waste gaseous streams (SOx and NOx, VOCs, H2S, NH3, siloxanes, halides, particulates, organic pollutants). This perspective article reports recent progresses in the applications of the membrane condenser in the treatment of various gaseous streams for water recovery and contaminant control. After an overview of the operating principle, the membranes used, and the main results achieved, the work also proposes the role of this technology as pre-treatment stage to other separation technologies. The potentialities of the technology are also discussed aspiring to pave the way towards the development of an innovative technology where membrane condenser can cover a key role in redesigning the whole upgrading process.


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