scholarly journals Acquired Elastotic Hemangioma: Case Series and Comprehensive Literature Review

Cureus ◽  
2017 ◽  
Author(s):  
Philip R Cohen ◽  
Brian R Hinds
Keyword(s):  
Literature Review ◽  
Case Series ◽  
Comprehensive Literature Review

Subcutaneous levetiracetam for the management of seizures at the end of life

2017 ◽  
Vol 8 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Anna Elizabeth Sutherland ◽  
John Curtin ◽  
Victoria Bradley ◽  
Olivia Bush ◽  
Maggie Presswood ◽  
...  
Keyword(s):  
Palliative Care ◽  
Literature Review ◽  
End Of Life ◽  
Terminal Care ◽  
Seizure Control ◽  
Case Reports ◽  
Subcutaneous Administration ◽  
Case Series ◽  
Comprehensive Literature Review ◽  
Randomised Controlled

ObjectivesTo report the results of a combined case series analysis of subcutaneous levetiracetam (Keppra) for the management of seizures in palliative care patients.MethodsA comprehensive literature review on the use of subcutaneous levetiracetam was performed, and these data were combined with a prospective observational audit of its use in terminal care undertaken in a regional palliative care network.Results7 papers were identified from the literature review-four case reports and three observational case series-reporting on a total of 53 cases where subcutaneous levetiracetam was administered.We report 20 further cases of subcutaneous levetiracetam administration from a prospective observational audit. Doses ranged from 250mg to 4000 mg daily. Oral to subcutaneous conversion ratios where stated were 1:1. Levetiracetam was reported as the sole administered antiepileptic drug (AED) in eight cases, and no seizures were reported until death in five cases. Five were switched back to enteral levetiracetam. In seven cases, levetiracetam was combined with AEDs to provide seizure control at the end of life. There was one report of a sterile abscess after 25 days of continuous subcutaneous administration.ConclusionsCombined analysis of 73 reported cases of subcutaneous levetiracetam suggests this treatment may have a role in the management of seizures at the end of life. However, randomised controlled trials are urgently needed to establish the efficacy and tolerability of subcutaneous levetiracetam administration. If proven to be safe and effective, subcutaneous levetiracetam offers the potential to prevent and treat seizures without causing unnecessary sedation at the end of life.

scholarly journals Burns associated with e-cigarette batteries: A case series and literature review

CJEM ◽  
2017 ◽  
Vol 20 (S2) ◽  
pp. S20-S28 ◽  
Author(s):  
Jamie Harshman ◽  
Miliana Vojvodic ◽  
Alan D. Rogers
Keyword(s):  
North America ◽  
Literature Review ◽  
Acute Care ◽  
Burn Injury ◽  
Electronic Cigarettes ◽  
Case Series ◽  
Burn Injuries ◽  
Injury Patterns ◽  
Comprehensive Literature Review ◽  
Appropriate Treatment

AbstractElectronic cigarettes, often referred to ase-cigarettes, have established a considerable market in North America over the last decade. In parallel to this trend, there has been a surge of e-cigarette battery explosions reported in the general media. Given the growing number of such events, acute care physicians should recognize the associated risks and injury patterns and initiate appropriate treatment. This report presents two cases of burn injuries from e-cigarette battery explosions requiring surgical management. The accompanying comprehensive literature review highlights the emerging importance of e-cigarettes as an aetiology of burn injury.

Bartonella and Coxiella infections presenting as systemic vasculitis: case series and review of literature

Rheumatology ◽  
2021 ◽  
Author(s):  
Maxime Beydon ◽  
Christophe Rodriguez ◽  
Alexandre Karras ◽  
Alexandre Cez ◽  
Cédric Rafat ◽  
...  
Keyword(s):  
Literature Review ◽  
Systemic Vasculitis ◽  
Case Series ◽  
Sequencing Analysis ◽  
Bacterial Dna ◽  
Anca Associated Vasculitis ◽  
Comprehensive Literature Review ◽  
Highly Sensitive ◽  
Next Generation Sequencing Analysis ◽  
Generation Sequencing

Abstract Objectives Coxiella and Bartonella sp. display particular tropism for endothelial or endocardial tissues and an abnormal host response to infections with induced autoimmunity. We aimed, through a case series combined with a comprehensive literature review, to outline characteristics of Coxiella and Bartonella infections presenting as systemic vasculitis. Methods We retrospectively included cases of definite Coxiella and Bartonella infections presenting with vasculitis features and performed a comprehensive literature review. Results Six cases of Bartonella infections were added to 18 cases from literature review. Causative pathogens were mainly B. henselae. Bartonella infection mimicked anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis in 83% with PR3-ANCA and presented as cryoglobulinemic vasculitis in 8%. Glomerulonephritis was present in 92%, and 88% had endocarditis. Complement fractions were low in 82% and rheumatoid factor positive in 85%. Kidney biopsies showed cell proliferation, mostly crescentic, with pauci-immune glomerulonephritis in 29%. Outcome was favorable, with the use of antibiotics alone in one third. Five cases of Coxiella infections were added to 16 from literature review. Sixteen had small-vessel vasculitides, mainly cryoglobulinemia vasculitis in 75%. One patient had polyarteritis nodosa-like vasculitis and four large-vessel vasculitis. Outcome was good except for one death. A highly sensitive next generation sequencing analysis on 3 Coxiella and 2 Bartonella-related vasculitides biopsies did not find any bacterial DNA. Conclusion Coxiella and Bartonella are both able to induce vasculitis but display distinct vasculitis features. Bartonella mimics PR3-ANCA-associated vasculitis in the setting of endocarditis, whereas Coxiella may induce vasculitis involving all vessel sizes.

Decreasing Suprapubic Tube-Related Injuries: Results of Case Series and Comprehensive Literature Review

2014 ◽  
Vol 34 (1) ◽  
pp. 9 ◽  
Author(s):  
Andrew J. Tompkins ◽  
Michelle Travis ◽  
Reed E. Watne ◽  
Michael Lasser ◽  
Pamela Ellsworth
Keyword(s):  
Literature Review ◽  
Case Series ◽  
Comprehensive Literature Review ◽  
Suprapubic Tube

scholarly journals Breast Cancer and Sarcoidosis: Case Series and Review of the Literature

Breast Care ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. 137-140 ◽  
Author(s):  
Jacob Chen ◽  
Robert Carter III ◽  
Daniel Maoz ◽  
Ana Tobar ◽  
Eran Sharon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Literature Review ◽  
Medical Center ◽  
Histological Study ◽  
Case Series ◽  
Chronic Inflammatory Disease ◽  
Unknown Etiology ◽  
Difficult Case ◽  
Comprehensive Literature Review ◽  
Rabin Medical

Background: Sarcoidosis is a chronic inflammatory disease of unknown etiology, which can involve different organs and systems. Accordingly, sarcoidosis can mimic breast cancer, making the differential diagnosis very difficult. Case Report: 5 patients with a diagnosis of both sarcoidosis and breast cancer followed by the Rabin Medical Center between January 1993 and June 2012 were enrolled in this study. Additionally, a comprehensive literature review which identified 104 patients diagnosed with breast cancer and sarcoidosis was carried out. In both populations reviewed, the average age at diagnosis of sarcoidosis and breast cancer was 57 years. Among the 66 patients with both sarcoidosis and breast cancer, sarcoidosis preceded breast cancer in 31 cases, followed it in 23 cases, and appeared concurrently in 10 cases. Conclusion: Based on our clinical cases and literature review, a histological study is recommended over imaging if sarcoidosis or breast cancer may be present. Furthermore, breast cancer is rarely associated with sarcoidosis or sarcoidosis-like reaction.

Surgical management of pituicytomas: case series and comprehensive literature review

Pituitary ◽  
2013 ◽  
Vol 17 (5) ◽  
pp. 399-413 ◽  
Author(s):  
Ming Feng ◽  
John D. Carmichael ◽  
Vivien Bonert ◽  
Serguei Bannykh ◽  
Adam N. Mamelak
Keyword(s):  
Literature Review ◽  
Surgical Management ◽  
Case Series ◽  
Comprehensive Literature Review
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