scholarly journals Burns associated with e-cigarette batteries: A case series and literature review

CJEM ◽  
2017 ◽  
Vol 20 (S2) ◽  
pp. S20-S28 ◽  
Author(s):  
Jamie Harshman ◽  
Miliana Vojvodic ◽  
Alan D. Rogers
Keyword(s):  
North America ◽  
Literature Review ◽  
Acute Care ◽  
Burn Injury ◽  
Electronic Cigarettes ◽  
Case Series ◽  
Burn Injuries ◽  
Injury Patterns ◽  
Comprehensive Literature Review ◽  
Appropriate Treatment

AbstractElectronic cigarettes, often referred to ase-cigarettes, have established a considerable market in North America over the last decade. In parallel to this trend, there has been a surge of e-cigarette battery explosions reported in the general media. Given the growing number of such events, acute care physicians should recognize the associated risks and injury patterns and initiate appropriate treatment. This report presents two cases of burn injuries from e-cigarette battery explosions requiring surgical management. The accompanying comprehensive literature review highlights the emerging importance of e-cigarettes as an aetiology of burn injury.

Subcutaneous levetiracetam for the management of seizures at the end of life

2017 ◽  
Vol 8 (2) ◽  
pp. 129-135 ◽  
Author(s):  
Anna Elizabeth Sutherland ◽  
John Curtin ◽  
Victoria Bradley ◽  
Olivia Bush ◽  
Maggie Presswood ◽  
...  
Keyword(s):  
Palliative Care ◽  
Literature Review ◽  
End Of Life ◽  
Terminal Care ◽  
Seizure Control ◽  
Case Reports ◽  
Subcutaneous Administration ◽  
Case Series ◽  
Comprehensive Literature Review ◽  
Randomised Controlled

ObjectivesTo report the results of a combined case series analysis of subcutaneous levetiracetam (Keppra) for the management of seizures in palliative care patients.MethodsA comprehensive literature review on the use of subcutaneous levetiracetam was performed, and these data were combined with a prospective observational audit of its use in terminal care undertaken in a regional palliative care network.Results7 papers were identified from the literature review-four case reports and three observational case series-reporting on a total of 53 cases where subcutaneous levetiracetam was administered.We report 20 further cases of subcutaneous levetiracetam administration from a prospective observational audit. Doses ranged from 250mg to 4000 mg daily. Oral to subcutaneous conversion ratios where stated were 1:1. Levetiracetam was reported as the sole administered antiepileptic drug (AED) in eight cases, and no seizures were reported until death in five cases. Five were switched back to enteral levetiracetam. In seven cases, levetiracetam was combined with AEDs to provide seizure control at the end of life. There was one report of a sterile abscess after 25 days of continuous subcutaneous administration.ConclusionsCombined analysis of 73 reported cases of subcutaneous levetiracetam suggests this treatment may have a role in the management of seizures at the end of life. However, randomised controlled trials are urgently needed to establish the efficacy and tolerability of subcutaneous levetiracetam administration. If proven to be safe and effective, subcutaneous levetiracetam offers the potential to prevent and treat seizures without causing unnecessary sedation at the end of life.

scholarly journals PMH64 MAJOR DEPRESSIVE DISORDER: A COMPREHENSIVE LITERATURE REVIEW OFTHE BURDEN OF ILLNESS IN NORTH AMERICA

2008 ◽  
Vol 11 (3) ◽  
pp. A129
Author(s):  
P Van Hanswijck de Jonge ◽  
M Stafford ◽  
S Hearn ◽  
N Tschaut ◽  
H Svedsater ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
North America ◽  
Literature Review ◽  
Depressive Disorder ◽  
Burden Of Illness ◽  
Major Depressive ◽  
Comprehensive Literature Review ◽  
Review Ofthe

scholarly journals Traumatic knee injury patterns in Anatolian folk dancers: a case series and literature review

2019 ◽  
Vol 32 (5) ◽  
pp. 585-593
Author(s):  
Neslihan Aksu ◽  
Busra Akgonul ◽  
Taner Aksu ◽  
Vefa Atansay ◽  
Ayhan Kara
Keyword(s):  
Literature Review ◽  
Knee Injury ◽  
Case Series ◽  
Injury Patterns

626 Causes and Injury Patterns of Elderly Burn Patients

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S158-S159
Author(s):  
Sam Miotke ◽  
Kathleen S Romanowski ◽  
Tina L Palmieri ◽  
David G Greenhalgh ◽  
Soman Sen
Keyword(s):  
Burn Injury ◽  
Body Part ◽  
Hot Water ◽  
Burn Injuries ◽  
Targeted Prevention ◽  
Age Group ◽  
Injury Patterns ◽  
Common Cause ◽  
Gender And Age ◽  
The Face

Abstract Introduction Older patients are a particularly vulnerable population with respect to burn injuries. The American Burn Association has invested resources in improving burn care and burn prevention within this age group, recognizing the difficulties in both the identification and subsequent modification of risk factors. The National Electronic Injury Surveillance System (NEISS) is maintained by the Consumer Product Safety Commission to surveil for injury trends and is populated with data from a representative group of approximately 100 emergency departments in the United States. This database could serve as a useful tool to evaluate burn injury patterns in elderly patients with an eye toward targeted prevention measures. Methods The NEISS was queried for patients aged 55 years and older with a diagnosis of scald, thermal, chemical, electrical, or unspecified burn injuries for the years 2008 - 2017. Each injury was classified by body part(s) burned, causative product, gender, and age group of patient (55–64, 65–74, 75–84, 85 and older). The ten most commonly burned sites as well as the ten most common causative products were determined for each gender and age group and in aggregate. Weighted estimates from the NEISS data were utilized to calculate injury numbers across the population. Results The most common etiology of burn injuries for all patients aged 55 and older was hot water. Men were most commonly injured by gasoline, a product which did not rank in the top ten for women in any age group. Additionally, within each age group, gasoline was among the top 4 products that was associated with burn injuries in men. Cookware was the second most common cause of burn injury among women aged 55 and older and was the sixth most common cause among men. For women, the combination of cookware and ranges/ovens was among the top 2 products associated with burn injury within each age group. The most commonly injured body part for all patients was the face. This held across most age and gender groupings except for women aged 75 to 84 (upper trunk), and women 85 and older (foot). Men were more likely to injure their hands than women. Conclusions The most common cause of burn injuries in older adults is hot water, and the most common body part affected is the face. Women are more likely to be injured by cookware and ranges/ovens. Men are more likely to be injured secondary to gasoline and are more likely to injure their hands. Applicability of Research to Practice NEISS data could be useful in the development of targeted prevention campaigns, such as focused education about the dangers of hot liquids, cooking, and accelerants.

64 E-cigarette and Vaporizer-related Burn Injury: Demographics and Injury Patterns

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S42-S42
Author(s):  
Kiran U Dyamenahalli ◽  
Derek M Wengryn ◽  
Arek J Wiktor ◽  
Elizabeth J Kovacs ◽  
Patrick Duffy ◽  
...  
Keyword(s):  
High School Students ◽  
Lung Injury ◽  
Burn Injury ◽  
Average Length ◽  
Demographic Data ◽  
Inpatient Admission ◽  
Burn Injuries ◽  
Product Regulatory ◽  
Injury Patterns ◽  
Media Reports

Abstract Introduction E-cigarettes and vaporizers (E-cigs) have seen a dramatic surge in popularity. The Centers for Disease Control now estimates that 1 in 4 United States (US) high school students use E-cigs. Recent recognition of E-cig-related lung injury has garnered significant attention. However, relatively little is known about E-cig-related burn injuries, which are often due to battery explosion and liquid ignition. The objective of this study was to characterize population demographics and injury patterns associated with E-cig burns. Methods A retrospective review of all patients presenting with E-cig-related cutaneous burn injury to a verified US burn center between January 2015 and August 2019 was performed using an institutional database. In addition, media reports covering the same mechanism of injury and date range were collected using databases for the National Electronic Injury Surveillance System, American Nonsmokers’ Rights Foundation, and international news outlets. Demographic data and injury metrics were recorded. Results 309 international media reports and 30 institutional cases of E-cig-related burn injuries were identified. Media-reported injuries varied with respect to geographic location: US-185, United Kingdom-35, Canada-6, all other countries-8, unclear-75. Annual incidence peaked in 2016 in media reports (2019-19, 2018–61, 2017–68, 2016–106, 2015–55) and institutional records (2019-3, 2018-5, 2017-6, 2016-16, 2015-0). Injuries predominantly involved men in both media (Male 75.7%, Female 13.9%, unknown 10.4%) and institutional (Male 93.3%, Female 6.7%) datasets. Average age was 31.0 years (media) and 30.3 years (institutional). The institutional data revealed an average TBSA of 3.5% (range 1–8.5%), an average length of stay of 3.8 days (range 0–14 days), and a median number of operations of 1 (range 0–2). 90% (n=27) of patients required inpatient admission and one patient required mechanical ventilation. On admission, 58% (n=14) of patients screened positive for cannabis use. A ranking of anatomic regions by frequency of involvement was consistent between datasets: lower extremity > hands > head/neck > torso > groin. Mortality rates were also similar: 1.62% (media) and 0% (institutional). Conclusions E-cig-related burns are non-trivial injuries, most of which require inpatient admission, operative management, and substantial resource use. They disproportionately affect young men and burns often involve sensitive areas like the hands and face. Applicability of Research to Practice Combined with rising popularity, lax regulation, proliferation of counterfeit products, and associated lung injury, E-cig-related burns represent an evolving health threat. This study highlights the importance of reporting injuries to consumer product regulatory agencies and the need for further research into the causes and consequences of E-cig explosion.

Bartonella and Coxiella infections presenting as systemic vasculitis: case series and review of literature

Rheumatology ◽  
2021 ◽  
Author(s):  
Maxime Beydon ◽  
Christophe Rodriguez ◽  
Alexandre Karras ◽  
Alexandre Cez ◽  
Cédric Rafat ◽  
...  
Keyword(s):  
Literature Review ◽  
Systemic Vasculitis ◽  
Case Series ◽  
Sequencing Analysis ◽  
Bacterial Dna ◽  
Anca Associated Vasculitis ◽  
Comprehensive Literature Review ◽  
Highly Sensitive ◽  
Next Generation Sequencing Analysis ◽  
Generation Sequencing

Abstract Objectives Coxiella and Bartonella sp. display particular tropism for endothelial or endocardial tissues and an abnormal host response to infections with induced autoimmunity. We aimed, through a case series combined with a comprehensive literature review, to outline characteristics of Coxiella and Bartonella infections presenting as systemic vasculitis. Methods We retrospectively included cases of definite Coxiella and Bartonella infections presenting with vasculitis features and performed a comprehensive literature review. Results Six cases of Bartonella infections were added to 18 cases from literature review. Causative pathogens were mainly B. henselae. Bartonella infection mimicked anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis in 83% with PR3-ANCA and presented as cryoglobulinemic vasculitis in 8%. Glomerulonephritis was present in 92%, and 88% had endocarditis. Complement fractions were low in 82% and rheumatoid factor positive in 85%. Kidney biopsies showed cell proliferation, mostly crescentic, with pauci-immune glomerulonephritis in 29%. Outcome was favorable, with the use of antibiotics alone in one third. Five cases of Coxiella infections were added to 16 from literature review. Sixteen had small-vessel vasculitides, mainly cryoglobulinemia vasculitis in 75%. One patient had polyarteritis nodosa-like vasculitis and four large-vessel vasculitis. Outcome was good except for one death. A highly sensitive next generation sequencing analysis on 3 Coxiella and 2 Bartonella-related vasculitides biopsies did not find any bacterial DNA. Conclusion Coxiella and Bartonella are both able to induce vasculitis but display distinct vasculitis features. Bartonella mimics PR3-ANCA-associated vasculitis in the setting of endocarditis, whereas Coxiella may induce vasculitis involving all vessel sizes.

The Psychological Effects of Burn Injuries: A Literature Review

1992 ◽  
Vol 55 (5) ◽  
pp. 198-201 ◽  
Author(s):  
Jo Fleet
Keyword(s):  
Social Support ◽  
Literature Review ◽  
Return To Work ◽  
Psychological Adjustment ◽  
Burn Injury ◽  
Psychological Effects ◽  
Burn Injuries ◽  
Professional Support ◽  
Adjustment Process

Revlous research identifies a number of variables that influence psychological adjustment following a burn injury. The aim of this literature review is to investigate the types of support available for adult burns patients and their value in the adjustment process and subsequent return to work. It concludes that social support is valuable during rehabilitation but that greater professional support is required.

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