scholarly journals Risk Factors Associated With Clostridium difficile-Associated Diarrhea

Cureus ◽  
2021 ◽  
Author(s):  
Aarzoo Gupta ◽  
FNU Savanti ◽  
Balvender Singh ◽  
Priyanka Sachdev ◽  
Deepak Raj ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Factors Associated ◽  
Clostridium Difficile Associated Diarrhea

scholarly journals INCIDENCE OF DIARRHEA BY Clostridium difficile IN HEMATOLOGIC PATIENTS AND HEMATOPOIETIC STEM CELL TRANSPLANTATION PATIENTS: RISK FACTORS FOR SEVERE FORMS AND DEATH

2014 ◽  
Vol 56 (4) ◽  
pp. 325-331 ◽  
Author(s):  
Fernanda Spadão ◽  
Juliana Gerhardt ◽  
Thais Guimarães ◽  
Frederico Dulley ◽  
João Nóbrega de Almeida Junior ◽  
...  
Keyword(s):  
Risk Factors ◽  
Stem Cell ◽  
Clostridium Difficile ◽  
Underlying Disease ◽  
Severe Form ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Factors Associated ◽  
Potential Factors ◽  
Clostridium Difficile Associated Diarrhea

We describe the rate of incidence of Clostridium difficile-associated diarrhea (CDAD) in hematologic and patients undergone stem cell transplant (HSCT) at HC-FMUSP, from January 2007 to June 2011, using two denominators 1,000 patient and 1,000 days of neutropenia and the risk factors associated with the severe form of the disease and death. The ELISA method (Ridascreen-Biopharm, Germany) for the detections of toxins A/B was used to identify C. difficile. A multivariate analysis was performed to evaluate potential factors associated with severe CDAD and death within 14 days after the diagnosis of CDAD, using multiple logistic regression. Sixty-six episodes were identified in 64 patients among 439 patients with diarrhea during the study period. CDA rate of incidence varied from 0.78 to 5.45 per 1,000 days of neutropenia and from 0.65 to 5.45 per 1,000 patient-days. The most common underlying disease was acute myeloid leukemia 30/64 (44%), 32/64 (46%) patients were neutropenic, 31/64 (45%) undergone allogeneic HSCT, 61/64 (88%) had previously used antibiotics and 9/64 (13%) have severe CDAD. Most of the patients (89%) received treatment with oral metronidazole and 19/64 (26%) died. The independent risk factors associated with death were the severe form of CDAD, and use of linezolid.

Risk Factors for Recurrence of Clostridium Difficile-associated Diarrhea in the Elderly

2002 ◽  
Vol 34 (8) ◽  
pp. 594-597 ◽  
Author(s):  
Sari Tal ◽  
Alexander Gurevich ◽  
Vladimir Guller ◽  
Irina Gurevich ◽  
David Berger ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
The Elderly ◽  
Risk Factors For Recurrence ◽  
Clostridium Difficile Associated Diarrhea

S1229 Risk Factors for Recurrent Clostridium difficile-Associated Diarrhea: A Retrospective Case-Control Study

2010 ◽  
Vol 138 (5) ◽  
pp. S-209
Author(s):  
Nabeel Koro ◽  
Yazan Abdalla ◽  
Fasiha Kanwal ◽  
Jay R. McDonald ◽  
Angelique L. Zeringue ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Clostridium Difficile Associated Diarrhea ◽  
Control Study

Clostridium difficile colitis in patients undergoing surgery for hip fractures: an analysis of 17,474 patients

2019 ◽  
Vol 30 (1) ◽  
pp. 22-32
Author(s):  
Azeem Tariq Malik ◽  
Carmen E Quatman ◽  
Laura S Phieffer ◽  
Thuan V Ly ◽  
Safdar N Khan
Keyword(s):  
Risk Factors ◽  
Hip Fracture ◽  
Clostridium Difficile ◽  
Hip Fractures ◽  
Healthcare Utilisation ◽  
Open Reduction Internal Fixation ◽  
Fracture Repair ◽  
Bundled Payment ◽  
Factors Associated ◽  
Incidence Risk

Background: We compiled evidence from a large national surgical database to identify the incidence, risk factors and postoperative impact of Clostridium difficile infection (CDI) in patients undergoing hip fracture repair. Methods: We identified 17,474 patients who underwent hip fracture repairs in 2015 using the ACS-NSQIP database. Interventions studied were open reduction/Internal fixation, total hip arthroplasty or hemiarthroplasty being performed for traumatic hip fractures. Outcomes studied were incidence, preoperative and postoperative risk factors for occurrence of CDI were studied using descriptive and statistical analysis. Results: A total of 92 patients (0.53%) developed CDI within 30 days of the operation. Following adjustment using multi-variate logistic regression, preoperative and hospital-associated factors associated with development of CDI were smoking (OR 1.75 [95% CI 1.03–2.99]), hypertension (OR 1.70 [95% CI 1.01–2.85]), hyponatraemia (OR 1.65 [95% CI 1.04–2.63]), prior systemic inflammatory response syndrome (SIRS) (OR 2.18 [95% CI 1.32-3.59]) and a length of stay >7 days (OR 1.98 [95% CI 1.11–3.53]. Postoperative factors associated with occurrence of CDI were occurrence of a deep surgical site infection (SSI) (OR 5.89 [95% CI 1.31–26.6]), a stay in the hospital >30 days (OR 6.56 [95% CI 2.56–16.9]) and unplanned reoperations (OR 2.78 [95% CI 1.29–5.99]). Conclusion: As we move toward an era of bundled-payment models, identification of risk factors associated with the occurrence of postoperative complications, such as CDI, will help curb excess healthcare utilisation and costs associated with the management of this complication.

scholarly journals Identification of Risk Factors for the Development of Clostridium difficile-Associated Diarrhea Following Treatment of Polymicrobial Surgical Infections

2010 ◽  
Vol 251 (4) ◽  
pp. 722-727 ◽  
Author(s):  
Rosemarie Metzger ◽  
Brian R. Swenson ◽  
Hugo Bonatti ◽  
Traci L. Hedrick ◽  
Tjasa Hranjec ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Surgical Infections ◽  
Clostridium Difficile Associated Diarrhea

Clostridium Difficile-Associated Diarrhea: Epidemiology, Risk Factors, and Infection Control

1997 ◽  
Vol 18 (9) ◽  
pp. 628-632 ◽  
Author(s):  
Kwan Kew Lai ◽  
Zita S. Melvin ◽  
Mary Jane Menard ◽  
Helen R. Kotilainen ◽  
Stephen Baker
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Infection Control ◽  
Clostridium Difficile Associated Diarrhea

scholarly journals Risk Factors Associated With Recurrent Clostridium difficile Infection

2019 ◽  
Vol 11 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Nikhita Dharbhamulla ◽  
Ahmed Abdelhady ◽  
Mona Domadia ◽  
Sanket Patel ◽  
John Gaughan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Factors Associated ◽  
Recurrent Clostridium Difficile Infection
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