scholarly journals Case of Colloid Nodular Goitre in a Rare Submandibular Location

Cureus ◽  
2021 ◽  
Author(s):  
Varsha Rangankar ◽  
Sameeh Uz Zaman ◽  
Krishnarjun Muralinath ◽  
Viraj P Shah ◽  
Pratiksha Yadav
Keyword(s):  
Nodular Goitre

TREATMENT OF NON-TOXIC GOITRE WITH THYROID PREPARATIONS

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 584-592 ◽  
Author(s):  
B.-A. Lamberg ◽  
C. A. Hernberg ◽  
Riitta Hakkila
Keyword(s):  
Radioactive Iodine ◽  
Response To Treatment ◽  
Iodine Uptake ◽  
Nodular Goitre ◽  
Radioactive Iodine Uptake ◽  
Observation Period

ABSTRACT Treatment with a thyroid preparation was used in 75 cases of non-toxic goitre. In 63 cases there was nodular goitre in 12 diffuse goitre. The observation period varied from 3 to 42 months. The size of the goitre decreased in 50 cases (68 per cent) of which 40 had a nodular goitre and 10 a diffuse goitre. In the 63 cases with a nodular goitre the size of the nodules decreased in 39 cases and the nodules disappeared completely in 2 cases (65 per cent). In 5 cases (7 per cent) there was no change in the size of the thyroid or the nodules. Temporary factitious hyperthyroidism appeared in 7 cases but subsided rapidly after adjustment of the dose. In one case an endogenous hyperthyroidism evidently developed, probably owing to initial latent hyperthyroidism. Treatment of non-toxic goitre with thyroid preparations or hormones is recommended 1) in diffuse goitre, 2) in nodular goitre as a trial and 3) after thyroidectomy for compressive goitre. The value of radioactive iodine uptake or excretion tests for the assessment of the response to treatment and the adjustment of the dose is emphasized.

The efficacy of radioiodine therapy in patients with non-toxic nodular goitre with large cold nodule

2015 ◽  
Author(s):  
Saeid Abdelrazek ◽  
Piotr Szumowski ◽  
Katrzyna Siewko ◽  
Janusz Mysliwiec ◽  
Malgorzata Szelachowska ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Toxic Nodular Goitre ◽  
Cold Nodule

Enzyme-linked immunosorbent assay of autoantibodies reacting with thyroid plasma membrane antigens in sera of patients with autoimmune thyroid diseases

1986 ◽  
Vol 113 (2) ◽  
pp. 255-260 ◽  
Author(s):  
Andrzej Gardas ◽  
Kathleen L. Rives
Keyword(s):  
Plasma Membrane ◽  
Immunosorbent Assay ◽  
Lupus Erythematosus ◽  
Antithyroid Drug ◽  
Cross Reactivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Autoimmune Thyroid Diseases ◽  
Nodular Goitre ◽  
Membrane Antigens ◽  
Toxic Nodular Goitre

Abstract. A sensitive and specific enzyme-linked immunosorbent assay (ELISA) for the detection of autoantibodies reacting with thyroid plasma membrane antigens has been established. Autoantibodies reacting with thyroid plasma membrane antigens were detected by the ELISA in 95% of untreated hyperthyroid Graves', 68% of antithyroid drug-treated Graves' up to four months of the therapy, in 62% of Hashimoto's thyroiditis and in 8.9% of toxic nodular goitre. The ELISA was negative in 100% healthy blood donors, 100% non-toxic nodular goitre, in 12 patients with rheumatoid arthritis, 18 patients with scleroderma and 94% of patients with systemic lupus erythematosus. The mean value of autoantibodies titre was higher in untreated hyperthyroid Graves' (1:84 000) and lowest in positive patients with autoimmune disease of non-thyroid origin (1:4000). The cross-reactivity of antimicrosomal antigen antibodies was below 10%; there was no influence of antithyroglobulin antibodies on the ELISA; and most of the autoantibodies react with plasma membrane antigens different from the TSH binding sites.

Development of hypothyroidism during long-term follow-up of patients with toxic nodular goitre after radioiodine therapy

2012 ◽  
Vol 76 (2) ◽  
pp. 297-303 ◽  
Author(s):  
Deniz Kahraman ◽  
Christian Keller ◽  
Christina Schneider ◽  
Wolfgang Eschner ◽  
Ferdinand Sudbrock ◽  
...  
Keyword(s):  
Radioiodine Therapy ◽  
Nodular Goitre ◽  
Long Term Follow Up ◽  
Toxic Nodular Goitre

THYROID CYTOLOGY AND IT'S INTERPRETATION WITH THYROID FUNCTION TEST

2021 ◽  
pp. 80-82
Author(s):  
Dipti Debbarma ◽  
Shipra Singh ◽  
Debarshi Jana ◽  
Chittaranjan Dutta
Keyword(s):  
Thyroid Gland ◽  
Thyroid Function ◽  
Nodular Goiter ◽  
Thyroid Function Test ◽  
Total Serum ◽  
Endocrine Glands ◽  
Nodular Goitre ◽  
Medical College ◽  
Euthyroid State ◽  
Function Test

INTRODUCTION: The Thyroid gland is unique among the endocrine glands. It is the largest of all the endocrine glands and it is supercial in location. It is the only gland which is easily approachable to direct physical, cytological and histopathological examination. The thyroid gland is affected by a variety of pathological lesions that are manifested by various morphologies including developmental, inammatory, hyperplastic and neoplastic pathology which are quiet common in the clinical practice. AIM OFTHE STUDY:In this study, we aimed to assess the cytological ndings of palpable thyroid nodules in conjunction with thyroid hormonal prole of the patient. To study the incidence in relevance to age, sex in various categories of thyroid lesions. MATERIALS & METHODS: Study Design: Institutional based Cross-sectional Study. Duration of study: January 2019 to August 2020. Source of data: Patients presenting to the OPD and admitted in the In-patient ward at Darbhanga Medical College, Bihar. Place of study: Department of Pathology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Sample Size: 60 patients of enlarged thyroid gland. RESULTS & OBSERVATIONS: We found that the 53.3% Patients are in euthyroid state. Nodular goitre is the most common nding. In the present study among 60 patients, Nodular goiter accounts for 83.3 % of all cases; 41.7% of them were in euthyroid state, 21.7 % in hypothyroid state , 8.3 % in subclinical hypothyroid and remaining 11.7 % in hyperthyroid state . SUMMARY AND CONCLUSION: FNAC together with thyroid function test (TFT) analysis leads to early and accurate diagnosis of various thyroid diseases and reduces surgical intervention. The study showed that FNAcytologic diagnosis cannot be used to predict thyroid function using total serum T4, T3 and TSH concentrations. Measurement of TSH, free T4, and free T3 would be preferable

Thyroid Carcinoma (Tc) in Nodular Goitre

2012 ◽  
Vol 01 (03) ◽  
Author(s):  
Nikhil Nanjappa BA ◽  
Alok Mohanty ◽  
Tirou Aroul T
Keyword(s):  
Thyroid Carcinoma ◽  
Nodular Goitre

scholarly journals European Thyroid Association Survey on Use of Minimally Invasive Techniques for Thyroid Nodules

2020 ◽  
Vol 9 (4) ◽  
pp. 194-204 ◽  
Author(s):  
Laszlo Hegedüs ◽  
Andrea Frasoldati ◽  
Roberto Negro ◽  
Enrico Papini
Keyword(s):  
Minimally Invasive ◽  
Online Survey ◽  
Needle Aspiration ◽  
Minimally Invasive Techniques ◽  
Ethanol Ablation ◽  
Old Patients ◽  
Nodular Goitre ◽  
Therapeutic Tools ◽  
Benign Nodules ◽  
Invasive Techniques

Objective: Image-guided interventional ultrasound (US) techniques represent diagnostic and therapeutic tools for non-surgical management of thyroid nodular disease. We sought to investigate the attitude of European Thyroid Association (ETA) members towards the use of minimally invasive techniques (MIT) in diagnosis/therapy of symptomatic nodular goitre. Methods: ETA members were invited to participate in an online survey investigating the use of MIT in benign and malignant thyroid nodular disease. Of 865 invited members, 221 (25.5%) completed the survey. The respondents were from 40 countries; 139 (74.7%) were from European countries. Results: Respondents personally performed thyroid US (91.6%), Fine needle aspiration (FNA; 75.3%), ethanol ablation (EA; 22.1%), core needle biopsy (CNB; 11%) and thermal treatments (4.8%). When skills and/or technology were unavailable, only 13.4% referred patients “often” or “always” to other centres with specific expertise in this field. Surgery was the preferred first option in patients with recurrent cysts, 4.0 cm benign nodules, local (radioiodine-avid or non-avid) lymph node metastases, or papillary cancers <1.0 cm. For autonomously functioning nodules radioactive iodine treatment was the preferred choice, followed by surgery. Thermal ablation (TA) was the preferred option only for a 4 cm benign nodule in old patients with comorbidities. Conclusions: US, US-guided FNA and surgery were available to nearly all respondents, while MIT was not. CNB and EA were employed only by about 1/3 of the respondents and TA procedures were available and personally performed only by a minority. For most thyroid lesions, surgery was the preferred option versus thermal therapies. The ETA needs to develop guidelines and establish teaching to overcome geographic inequality and promote the use of MIT as a valid therapy option in appropriate cases.

Nodular Goitre in Northern India: A Clinicopathological Profile

1975 ◽  
Vol 45 (2) ◽  
pp. 197-201
Author(s):  
A. Prakash ◽  
Lalit K. Sharma ◽  
A. Koshal ◽  
Ch. S. P. Rao ◽  
M. M. S. Ahuja
Keyword(s):  
Nodular Goitre ◽  
Northern India ◽  
Clinicopathological Profile
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