scholarly journals Listeria Bacteremia Presenting With Cerebral Abscess and Endocarditis in an Elderly Patient With Chronic Immune Thrombocytopenia

Cureus ◽  
2021 ◽  
Author(s):  
Olushola O Ogunleye ◽  
Vanessa Karimi ◽  
Nili Gujadhur
Keyword(s):  
Elderly Patient ◽  
Immune Thrombocytopenia ◽  
Cerebral Abscess ◽  
Chronic Immune Thrombocytopenia

Ischemic Stroke in the Setting of Chronic Immune Thrombocytopenia in an Elderly Patient—A Therapeutic Dilemma

2011 ◽  
Vol 18 (3) ◽  
pp. 324-326 ◽  
Author(s):  
Anna De La Peña ◽  
Jawed Fareed ◽  
Indermohan Thethi ◽  
Sarkis Morales-Vidal ◽  
Michael J. Schneck ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Ischemic Stroke ◽  
Immune Thrombocytopenia ◽  
Chronic Immune Thrombocytopenia

scholarly journals Effects of Rapamycin Combined with Low Dose Prednisone in Patients with Chronic Immune Thrombocytopenia

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Jiaming Li ◽  
Zhaoyue Wang ◽  
Lan Dai ◽  
Lijuan Cao ◽  
Jian Su ◽  
...  
Keyword(s):  
Immune Thrombocytopenia ◽  
Low Dose ◽  
Group Versus ◽  
Treg Cells ◽  
Significant Rise ◽  
Control Group ◽  
Foxp3 Mrna ◽  
Experimental Group ◽  
Dose Prednisone ◽  
Chronic Immune Thrombocytopenia

We conducted this randomized trial to investigate the efficacy and safety of rapamycin treatment in adults with chronic immune thrombocytopenia (ITP). Eighty-eight patients were separated into the control (cyclosporine A plus prednisone) and experimental (rapamycin plus prednisone) groups. The CD4+CD25+CD127lowregulatory T (Treg) cells level, Foxp3 mRNA expression, and the relevant cytokines levels were measured before and after treatment. The overall response (OR) was similar in both groups (experimental group versus control group: 58% versus 62%,P=0.70). However, sustained response (SR) was more pronounced in the experimental group than in the control group (68% versus 39%,P<0.05). Both groups showed similar incidence of adverse events (7% versus 11%,P=0.51). As expected, the low pretreatment baseline level of Treg cells was seen in all patients (P<0.001); however, the experimental group experienced a significant rise in Treg cell level, and there was a strong correlation between the levels of Treg cells and TGF-beta after the treatment. In addition, the upregulation maintained a stable level during the follow-up phase. Thus, rapamycin plus low dose prednisone could provide a new promising option for therapy of ITP.

An analysis of outcomes and treatment costs for children undergoing splenectomy for chronic immune thrombocytopenia purpura

2012 ◽  
Vol 47 (8) ◽  
pp. 1537-1541 ◽  
Author(s):  
Natalie R. Gwilliam ◽  
David A. Lazar ◽  
Mary L. Brandt ◽  
Donald H. Mahoney ◽  
David E. Wesson ◽  
...  
Keyword(s):  
Immune Thrombocytopenia ◽  
Treatment Costs ◽  
Immune Thrombocytopenia Purpura ◽  
Chronic Immune Thrombocytopenia
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