scholarly journals Combination therapy in relapsed or refractory chronic immune thrombocytopenia: a case report and literature review

2016 ◽  
Vol 41 (5) ◽  
pp. 453-458 ◽  
Author(s):  
A. Rashidi ◽  
M. A. Blinder
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Combination Therapy ◽  
Immune Thrombocytopenia ◽  
Chronic Immune Thrombocytopenia

Autoimmune pancytopenia following chronic immune thrombocytopenia: Case report and literature review

2020 ◽  
Vol 84 ◽  
pp. 102455
Author(s):  
Angelo Gardellini ◽  
Francesca Guidotti ◽  
Michelle Zancanella ◽  
Vittoria Saccà ◽  
Maddalena Feltri ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Immune Thrombocytopenia ◽  
Chronic Immune Thrombocytopenia

scholarly journals Combination therapy with bosentan and sildenafil for refractory digital ulcers and Raynaud’s phenomenon in a 30-year-old woman with systemic sclerosis: Case report and literature review

2019 ◽  
Vol 5 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Jan-Gerd Rademacher ◽  
Chris Wincup ◽  
Björn Tampe ◽  
Peter Korsten
Keyword(s):  
Case Report ◽  
Systemic Sclerosis ◽  
Literature Review ◽  
Combination Therapy ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Digital Ulcers ◽  
Channel Blockers ◽  
Tissue Necrosis ◽  
Diffuse Systemic Sclerosis

Background: Systemic sclerosis is a rare autoimmune disease characterized by skin and organ fibrosis, and vasculopathy. Raynaud’s phenomenon is almost universally present in systemic sclerosis and can be the most debilitating symptom. Raynaud’s phenomenon may lead to the development of digital ulcers, potentially complicated by infection, tissue necrosis, and auto-amputation. Recommended treatments have variable efficacy. Methods: We report the case of a 30-year-old woman with diffuse systemic sclerosis suffering from severe Raynaud’s phenomenon and digital ulcers with digital tissue necrosis who was treated with combination therapy of an endothelin receptor antagonist and phosphodiesterase 5 inhibitor. In addition, we reviewed the literature on the topic. Results: Previous therapy with calcium-channel blockers, intravenous iloprost, and bosentan had all failed to control symptoms. We added sildenafil in combination with bosentan and observed a rapid and sustained treatment effect. Raynaud’s phenomenon severity, number of attacks, and attack duration decreased within 2 weeks of initiating treatment. Furthermore, this resulted in the healing of established digital ulcers. Conclusion: Our case report suggests that combination therapy may be a feasible treatment for the most severely affected and refractory patients. In our literature review, we found one retrospective study and three additional cases with similarly encouraging results.

scholarly journals Treatment of Secondary Immune Thrombocytopenia with Non-Hodgkin Lymphoma: A Case Report and Literature Review

2021 ◽  
Vol 60 (10) ◽  
pp. 1583-1588
Author(s):  
Yuya Kurihara ◽  
Kazuki Taoka ◽  
Eri Takagi ◽  
Kazuhiro Toyama ◽  
Kumi Nakazaki ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Hodgkin Lymphoma ◽  
Immune Thrombocytopenia ◽  
Non Hodgkin Lymphoma

scholarly journals Immune thrombocytopenia in patient with clear cell renal carcinoma: case report and literature review

2020 ◽  
Vol 4 (1) ◽  
pp. 26-27
Author(s):  
Mart nez-Cordero Humberto ◽  
Salgado-Reyes Paula ◽  
Alcala-Lara Sebastian ◽  
Linares- Pati o ◽  
Maximo Mejia ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Immune Thrombocytopenia ◽  
Renal Carcinoma ◽  
Clear Cell ◽  
Clear Cell Renal Carcinoma ◽  
Cell Renal Carcinoma

scholarly journals Novel Coronavirus Disease 2019 (COVID-19) and Combined Autoimmune Neutropenia (AIN) and Thrombocytopenia (ITP): A Case Report and Literature Review

2020 ◽  
pp. 1-2
Author(s):  
Rizvi M ◽  
◽  
Medar S ◽  
Keyword(s):  
Platelet Count ◽  
Case Report ◽  
Literature Review ◽  
Rare Disease ◽  
Neutrophil Count ◽  
Immune Thrombocytopenia ◽  
The Novel ◽  
Autoimmune Neutropenia ◽  
First Case ◽  
Novel Coronavirus

Combined autoimmune neutropenia (AIN) and Immune thrombocytopenia (ITP) is a rare disease that can present as extremely low neutrophil count and platelet count, respectively [1]. We describe the first case, to our knowledge, of the novel SARS CoV-2 infection and combined autoimmune neutropenia (AIN) and immune thrombocytopenia (ITP) in a healthy 27-year-old male

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