scholarly journals Dosimetric Comparison of Whole Breast Radiotherapy Using Field-in-Field and Volumetric Modulated Arc Therapy Techniques in Left-Sided Breast Cancer Patients

Cureus ◽  
2021 ◽  
Author(s):  
Asmara Waheed ◽  
Sumera Butt ◽  
Ali Ishtiaq ◽  
Muhammad Atif Mansha ◽  
Sana Mehreen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Breast Cancer Patients ◽  
Breast Radiotherapy ◽  
Dosimetric Comparison ◽  
Whole Breast Radiotherapy ◽  
Arc Therapy

Volumetric Modulated Arc Therapy Dose Distribution Prediction for Breast Cancer Patients: CNN Approach

2021 ◽  
Author(s):  
Zuzanna Krawczyk ◽  
Robert Szmurlo ◽  
Pawel Zawadzki ◽  
Estera Kot ◽  
Jacek Starzynski ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Dose Distribution ◽  
Volumetric Modulated Arc Therapy ◽  
Breast Cancer Patients ◽  
Arc Therapy

Longterm blood cell counts after intraoperative radiotherapy with or without whole breast radiotherapy in breast cancer patients.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e12014-e12014
Author(s):  
Elena Sperk ◽  
Cornelia Wersal ◽  
Christel Weiss ◽  
Anke Keller ◽  
Anette Kipke ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Blood Cell ◽  
Cancer Patients ◽  
Cell Lines ◽  
Breast Cancer Patients ◽  
Breast Radiotherapy ◽  
Cell Counts ◽  
Blood Cell Counts ◽  
Whole Breast Radiotherapy

e12014 Background: After radiotherapy changes in blood cell counts (BCC) can be seen. Leukocytopenia may have a negative impact on the immune system, outcome and quality of life of breast cancer survivors. No reports on changes of the three blood cell lines (leukocytes=WBC, erythrocytes=RBC, thrombocytes=PLT) after IORT w/o whole breast radiotherapy (WBRT) in breast cancer patients have been reported. Methods: 256 patients had IORT during breast conserving surgery. In 198 patients WBRT (46-50Gy/2Gy) + IORT (20Gy) and in 58 patients IORT as accelerated partial breast irradiation=APBI (20Gy) was given. Preoperative BCC were used as baseline. In 214 patients BCC were available after 1-90 days, in 139 during the 1st year, in 86 in the 2nd, in 66 in the 3rd, in 51 in the 4th and in 34 in the 5th year of follow-up. Dunnett-tests were used to calculate adjusted p-values (p<0.05=significant). Results: After IORT/WBRT a decrease of WBC was seen during the 1st year. Afterwards no changes were seen. After IORT APBI no changes were seen during 5 years follow-up. RBC was decreased at all time points after IORT/WBRT, and through the 1st year after IORT APBI. PLT decreased during the 1st year and stayed low during 5 years after IORT/WBRT. No changes in PLT were seen after IORT APBI. Hemoglobin (HGB) decreased after 3 months, during the 1st and 5th year after IORT/WBRT. After IORT APBI, HGB decreased only during the 1st year and stayed stable during follow-up. Conclusions: Decreases of all blood cell lines were seen at least transiently after IORT/WBRT. PLT and RBC stayed decreased. After IORT APBI, HGB and RBC decreased only during the 1st year and WBC and PLT remained stable during the whole follow-up. [Table: see text]

Volumetric modulated arc therapy (VMAT) to deliver nodal irradiation in breast cancer patients

2017 ◽  
Vol 35 (1) ◽  
Author(s):  
Giuseppe Carlo Iorio ◽  
Pierfrancesco Franco ◽  
Elena Gallio ◽  
Stefania Martini ◽  
Francesca Arcadipane ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Volumetric Modulated Arc Therapy ◽  
Breast Cancer Patients ◽  
Arc Therapy

scholarly journals Quantifying the Mitigating Effects of Whole-Breast Radiotherapy and Systemic Treatments on Regional Recurrence Incidence Among Breast Cancer Patients

2020 ◽  
Vol 27 (9) ◽  
pp. 3402-3411 ◽  
Author(s):  
Julia E. C. van Steenhoven ◽  
Anne Kuijer ◽  
Marissa C. van Maaren ◽  
Marleen Roos ◽  
Sjoerd G. Elias ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Regional Recurrence ◽  
Breast Cancer Patients ◽  
Breast Radiotherapy ◽  
Systemic Treatments ◽  
Whole Breast Radiotherapy

Left Breast Radiotherapy With Multi Fields Hybrid Intensity Modulated Radiotherapy (IMRT) Versus Volumetric Modulated Arc Therapy (VMAT): Balance Between Left Anterior Descending Artery Sparing and Secondary Cancer Induction Risk

2021 ◽  
Author(s):  
Xiaoyong Xiang ◽  
Zhen Ding ◽  
Kailian Kang ◽  
Zhitao Dai ◽  
Wenjue Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Volumetric Modulated Arc Therapy ◽  
Left Lung ◽  
Breast Conserving Surgery ◽  
Left Breast ◽  
High Dose ◽  
Breast Cancer Patients ◽  
Breast Radiotherapy ◽  
Breast Cancer Radiotherapy ◽  
Arc Therapy

Abstract To explore the feasibility of using Volumetric-Modulated Arc Therapy (VMAT) to protect left anterior descending branch (LAD) after breast-conserving surgery for left breast cancer. 15 left breast cancer patients after breast-conserving surgery were selected. 7F-IMRT and 2A-VMAT treatment plans were designed with Varian Eclipse TPS (13.6version). The prescriptions of PTV and PTV Boost were 43.5Gy and 49.5Gy in 15 fractions. The dosimetric parameters, OARs dose sparing and second cancer risk (SCR) were compared between the two plans using a paired t-test. The VMAT plans obtain better PTV conformity and higher mean dose. VMAT plans show a better dose distribution in high dose areas and better sparing of OARs, including left lung, heart, and LAD. The Dmax and Dmean of LAD decreased significantly in VMAT plans. The SCRs of the contralateral lung and breast significantly increased with a higher mean dose. We recommend that contouring and evaluating the dose of LAD and LAD helping structures in left breast cancer radiotherapy. SCR should be evaluated for younger patients.

Sign in / Sign up

Export Citation Format

Share Document