scholarly journals Esophageal Schwannoma: A Rare Benign Esophageal Tumor

Cureus ◽  
2021 ◽  
Author(s):  
Rasiq Zackria ◽  
Eric H Choi
2003 ◽  
Vol 38 (5) ◽  
pp. 1125-1129 ◽  
Author(s):  
Kuniyoshi Tanaka ◽  
Akio Ihaya ◽  
Tetsuya Horiuci ◽  
Koich Morioka ◽  
Tetsuya Kimura ◽  
...  

2021 ◽  
Vol 8 (7) ◽  
pp. 2166
Author(s):  
Ambreen Abid ◽  
Tanveer Ahmad ◽  
Misauq Mazcuri ◽  
Nazish Sikander

Leiomyoma are rare esophageal masses. Majority remain asymptomatic but may present with dysphagia when more than five centimeters in size. Barium swallow is the initial diagnostic investigation. Small lesion can be observed. Symptomatic and large lesion should undergo prompt surgical enucleation. Here we presented a case of a 35 year old female presenting with progressive dysphagia and gradual weight loss for 5 years along with regurgitation for one year. Clinical examination was unremarkable. Barium study was suggestive of smooth intramural defect with normal mucosa. Computed tomography showed well defined homogenous opacity located intramuraly at the level of junction of middle and distal third of esophagus with normal surrounding structures. Surgical enucleation was done through a right posterolateral thoracotomy. Muscle defect was repaired and checked for possible leaks. Liquid diet was commenced on 5th postoperative day. Patient was discharged on semisolid diet for two weeks with progression to solid meal.


1977 ◽  
Vol 22 (3) ◽  
pp. 266-269 ◽  
Author(s):  
John L. Orchard ◽  
Wayne W. Peternel ◽  
Sebastian Arena

2021 ◽  
Vol 9 ◽  
pp. 2050313X2199719
Author(s):  
Sundus Bilal ◽  
Saad Muhammad Saeed ◽  
Muhammad Zeeshan Siddique ◽  
Muhammad Saqib ◽  
Shafqat Mehmood ◽  
...  

The role of self-expandable metallic stents is gradually evolving for a diverse group of benign and malignant gastrointestinal tract problems, with luminal obstruction being by far the most common. Although its role in refractory variceal bleeding is well established, it has rarely been tried for tumor-related bleeding, with only a few case reports in this regard. We share our experience of successfully controlling esophageal tumor–related bleeding with the use of a fully covered self-expandable metallic stent. A 58-year-old woman with irresectable distal esophageal cancer, presented with hematemesis. Esophago-gastro-duodenoscopy revealed an obstructing esophageal tumor with diffuse oozing of blood. This was unamenable to local injection of adrenaline and hemospray; therefore, a temporary self-expandable metallic stent was parked to create a tamponade effect. This successfully stopped bleeding and the patient remained asymptomatic till discharge. However, she was lost to follow-up, and therefore, the stent was removed after a period of 5 months instead of 2 weeks.


2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 172-172
Author(s):  
Yoshifumi Baba ◽  
Taisuke Yagi ◽  
Yuki Kiyozumi ◽  
Yukiharu Hiyoshi ◽  
Masaaki Iwatsuki ◽  
...  

Abstract Background In cancer cells, DNA methylation may be altered in two principle ways; global DNA hypomethylation and site-specific CpG island promoter hypermethylation. Since Long interspersed element-1 (LINE-1 or L1; a repetitive DNA retrotransposon) constitutes a substantial portion (approximately 17%) of the human genome, the extent of LINE-1 methylation is regarded as a surrogate marker of global DNA methylation. In previous studies, we demonstrated that LINE-1 hypomethylation was strongly associated with a poor prognosis in esophageal cancer, supporting its potential role as a prognostic marker (Ann Surg 2012). We also found that LINE-1-hypomethylated tumors showed highly frequent genomic gains at various loci containing candidate oncogenes such as CDK6 (Clin Cancer Res 2014). Given that immunotherapy, as represented by PD-1/PD-L1-targeting antibodies, has increasingly gained attention as a novel treatment strategy for esophageal cancer, better understanding of local immune response status in esophageal cancer is important. The aim of this study is to evaluate the relationship between LINE-1 methylation level and local immune response in esophageal cancer. Methods Using a non-biased database of 305 curatively resected esophageal cancers, we evaluated PD-L1 expression and TIL status (CD8 expression) by immunohistochemical analysis (Ann Surg 2017). Results TIL positivity was significantly correlated with longer overall survival (log-rank P < 0.0001). TIL-negative cases demonstrated significantly lower LINE-1 methylation level compared with TIL-positive cases (P = 0.012). This finding certainly supports that LINE-1 methylation level may influence the local immune response status. Conclusion PD-L1 expression was not related with LINE-1 methylation level. Further investigations in this field would provide deeper insights into esophageal tumor immunology and assist the development of new therapeutic strategies against esophageal cancer. Disclosure All authors have declared no conflicts of interest.


2013 ◽  
Vol 11 (1) ◽  
pp. 253 ◽  
Author(s):  
Masahiro Kitada ◽  
Yoshinari Matsuda ◽  
Satoshi Hayashi ◽  
Kei Ishibashi ◽  
Kensuke Oikawa ◽  
...  

2014 ◽  
Vol 46 (2) ◽  
pp. 90-95 ◽  
Author(s):  
K. Dalcı ◽  
O. Yalav ◽  
A. Rencuzogulları ◽  
I. C. Eray ◽  
C. Ozcelik ◽  
...  

1997 ◽  
Vol 78 (5) ◽  
pp. 387-387
Author(s):  
R. M. Taziev ◽  
I. F. Rabbaniev ◽  
L. I. Pustilnik ◽  
E. I. Sigal ◽  
V. P. Potanin ◽  
...  

One of the serious complications of esophageal diverticula is the development of cancer in it. In epiphrenal diverticula malignization is more frequent than in bifurcation diverticula. On the basis of statistical data analysis I.T. Shevchenko (1950) established that tumor in pulsatile diverticulum occurs in 1.2% of cases and in traction one - in 7.8%. In his opinion, one of the causes of esophageal tumor is a tractional diverticulum.


2016 ◽  
Vol 9 ◽  
pp. CGast.S40605 ◽  
Author(s):  
Nikhil Sonthalia ◽  
Samit S. Jain ◽  
Ravindra G. Surude ◽  
Vinay B. Pawar ◽  
Suhas Udgirkar ◽  
...  

Esophageal squamous cell carcinoma (ESCC) is the commonest primary malignant esophageal tumor, which typically presents as endoscopically visible surface mucosal ulcerations, irregularities, or polyploidal masses. We here report a rare case of primary ESCC with completely intramural growth under a normal looking intact nondysplastic surface squamous epithelium disguising as a submucosal tumor. Upper gastrointestinal endoscopy-guided mucosal biopsy was negative for malignancy. Endoscopic ultrasound (EUS) revealed a heteroechoic solid mass originating from the muscularis propria of the distal esophagus. Cytological study of EUS-guided fine needle aspiration from the mass was suggestive of squamous cell carcinoma, which was confirmed on immunohistochemistry. There was no evidence of metastatic origin of this tumor or continuous cancer involvement from the surrounding structures, including the head, neck, and lungs on bronchoscopy, computed tomography scan, and positron emission tomography scan. Exclusive intramural squamous cell carcinoma with normal overlying mucosa is an exceedingly rare presentation of primary ESCC with only four cases reported in the literature so far. A high index of suspicion is required by the gastroenterologists and pathologists in diagnosing these cases as these tumors closely mimic the mesenchymal submucosal tumors such as lipoma, leiomyoma, and gastrointestinal stromal tumors. EUS is an indispensable tool in making a preoperative diagnosis and therapeutic decision making.


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