Remarkably large, benign esophageal tumor

1977 ◽  
Vol 22 (3) ◽  
pp. 266-269 ◽  
Author(s):  
John L. Orchard ◽  
Wayne W. Peternel ◽  
Sebastian Arena
Keyword(s):  
Esophageal Tumor ◽  
Benign Esophageal Tumor

scholarly journals Giant mediastinal bronchial artery aneurysm mimicking benign esophageal tumor: a case report and review of 26 cases from literature

2003 ◽  
Vol 38 (5) ◽  
pp. 1125-1129 ◽  
Author(s):  
Kuniyoshi Tanaka ◽  
Akio Ihaya ◽  
Tetsuya Horiuci ◽  
Koich Morioka ◽  
Tetsuya Kimura ◽  
...  
Keyword(s):  
Case Report ◽  
Bronchial Artery ◽  
Artery Aneurysm ◽  
Esophageal Tumor ◽  
Bronchial Artery Aneurysm ◽  
Benign Esophageal Tumor

scholarly journals Leiomyoma an uncommon benign esophageal tumor

2021 ◽  
Vol 8 (7) ◽  
pp. 2166
Author(s):  
Ambreen Abid ◽  
Tanveer Ahmad ◽  
Misauq Mazcuri ◽  
Nazish Sikander
Keyword(s):  
Normal Mucosa ◽  
Barium Swallow ◽  
Small Lesion ◽  
Esophageal Tumor ◽  
Barium Study ◽  
Diagnostic Investigation ◽  
Solid Meal ◽  
One Year ◽  
Benign Esophageal Tumor ◽  
Progressive Dysphagia

Leiomyoma are rare esophageal masses. Majority remain asymptomatic but may present with dysphagia when more than five centimeters in size. Barium swallow is the initial diagnostic investigation. Small lesion can be observed. Symptomatic and large lesion should undergo prompt surgical enucleation. Here we presented a case of a 35 year old female presenting with progressive dysphagia and gradual weight loss for 5 years along with regurgitation for one year. Clinical examination was unremarkable. Barium study was suggestive of smooth intramural defect with normal mucosa. Computed tomography showed well defined homogenous opacity located intramuraly at the level of junction of middle and distal third of esophagus with normal surrounding structures. Surgical enucleation was done through a right posterolateral thoracotomy. Muscle defect was repaired and checked for possible leaks. Liquid diet was commenced on 5th postoperative day. Patient was discharged on semisolid diet for two weeks with progression to solid meal.

scholarly journals Salvage therapy of bleeding esophageal tumor by fully covered self-expandable metallic stent: A case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2199719
Author(s):  
Sundus Bilal ◽  
Saad Muhammad Saeed ◽  
Muhammad Zeeshan Siddique ◽  
Muhammad Saqib ◽  
Shafqat Mehmood ◽  
...  
Keyword(s):  
Case Reports ◽  
Esophageal Tumor ◽  
Metallic Stent ◽  
Diverse Group ◽  
Expandable Metallic Stent ◽  
Lost To Follow Up ◽  
Expandable Metallic Stents ◽  
Tamponade Effect

The role of self-expandable metallic stents is gradually evolving for a diverse group of benign and malignant gastrointestinal tract problems, with luminal obstruction being by far the most common. Although its role in refractory variceal bleeding is well established, it has rarely been tried for tumor-related bleeding, with only a few case reports in this regard. We share our experience of successfully controlling esophageal tumor–related bleeding with the use of a fully covered self-expandable metallic stent. A 58-year-old woman with irresectable distal esophageal cancer, presented with hematemesis. Esophago-gastro-duodenoscopy revealed an obstructing esophageal tumor with diffuse oozing of blood. This was unamenable to local injection of adrenaline and hemospray; therefore, a temporary self-expandable metallic stent was parked to create a tamponade effect. This successfully stopped bleeding and the patient remained asymptomatic till discharge. However, she was lost to follow-up, and therefore, the stent was removed after a period of 5 months instead of 2 weeks.

PS02.176: LINE-1 METHYLATION LEVEL AND LOCAL IMMUNE RESPONSE IN ESOPHAGEAL CANCER

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 172-172
Author(s):  
Yoshifumi Baba ◽  
Taisuke Yagi ◽  
Yuki Kiyozumi ◽  
Yukiharu Hiyoshi ◽  
Masaaki Iwatsuki ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Immune Response ◽  
Esophageal Cancer ◽  
Methylation Level ◽  
Cpg Island ◽  
Surrogate Marker ◽  
Esophageal Tumor ◽  
Local Immune Response ◽  
Dna Hypomethylation ◽  
Response Status

Abstract Background In cancer cells, DNA methylation may be altered in two principle ways; global DNA hypomethylation and site-specific CpG island promoter hypermethylation. Since Long interspersed element-1 (LINE-1 or L1; a repetitive DNA retrotransposon) constitutes a substantial portion (approximately 17%) of the human genome, the extent of LINE-1 methylation is regarded as a surrogate marker of global DNA methylation. In previous studies, we demonstrated that LINE-1 hypomethylation was strongly associated with a poor prognosis in esophageal cancer, supporting its potential role as a prognostic marker (Ann Surg 2012). We also found that LINE-1-hypomethylated tumors showed highly frequent genomic gains at various loci containing candidate oncogenes such as CDK6 (Clin Cancer Res 2014). Given that immunotherapy, as represented by PD-1/PD-L1-targeting antibodies, has increasingly gained attention as a novel treatment strategy for esophageal cancer, better understanding of local immune response status in esophageal cancer is important. The aim of this study is to evaluate the relationship between LINE-1 methylation level and local immune response in esophageal cancer. Methods Using a non-biased database of 305 curatively resected esophageal cancers, we evaluated PD-L1 expression and TIL status (CD8 expression) by immunohistochemical analysis (Ann Surg 2017). Results TIL positivity was significantly correlated with longer overall survival (log-rank P < 0.0001). TIL-negative cases demonstrated significantly lower LINE-1 methylation level compared with TIL-positive cases (P = 0.012). This finding certainly supports that LINE-1 methylation level may influence the local immune response status. Conclusion PD-L1 expression was not related with LINE-1 methylation level. Further investigations in this field would provide deeper insights into esophageal tumor immunology and assist the development of new therapeutic strategies against esophageal cancer. Disclosure All authors have declared no conflicts of interest.

Esophageal diverticular cancer

1997 ◽  
Vol 78 (5) ◽  
pp. 387-387
Author(s):  
R. M. Taziev ◽  
I. F. Rabbaniev ◽  
L. I. Pustilnik ◽  
E. I. Sigal ◽  
V. P. Potanin ◽  
...  
Keyword(s):  
Data Analysis ◽  
Statistical Data ◽  
Esophageal Tumor ◽  
Statistical Data Analysis ◽  
Esophageal Diverticula

One of the serious complications of esophageal diverticula is the development of cancer in it. In epiphrenal diverticula malignization is more frequent than in bifurcation diverticula. On the basis of statistical data analysis I.T. Shevchenko (1950) established that tumor in pulsatile diverticulum occurs in 1.2% of cases and in traction one - in 7.8%. In his opinion, one of the causes of esophageal tumor is a tractional diverticulum.

scholarly journals Primary Esophageal Intramural Squamous Cell Carcinoma Masquerading as a Submucosal Tumor: A Rare Presentation of a Common Disease

2016 ◽  
Vol 9 ◽  
pp. CGast.S40605 ◽  
Author(s):  
Nikhil Sonthalia ◽  
Samit S. Jain ◽  
Ravindra G. Surude ◽  
Vinay B. Pawar ◽  
Suhas Udgirkar ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Submucosal Tumor ◽  
Muscularis Propria ◽  
Upper Gastrointestinal Endoscopy ◽  
Common Disease ◽  
Esophageal Tumor ◽  
Rare Presentation ◽  
Tomography Scan

Esophageal squamous cell carcinoma (ESCC) is the commonest primary malignant esophageal tumor, which typically presents as endoscopically visible surface mucosal ulcerations, irregularities, or polyploidal masses. We here report a rare case of primary ESCC with completely intramural growth under a normal looking intact nondysplastic surface squamous epithelium disguising as a submucosal tumor. Upper gastrointestinal endoscopy-guided mucosal biopsy was negative for malignancy. Endoscopic ultrasound (EUS) revealed a heteroechoic solid mass originating from the muscularis propria of the distal esophagus. Cytological study of EUS-guided fine needle aspiration from the mass was suggestive of squamous cell carcinoma, which was confirmed on immunohistochemistry. There was no evidence of metastatic origin of this tumor or continuous cancer involvement from the surrounding structures, including the head, neck, and lungs on bronchoscopy, computed tomography scan, and positron emission tomography scan. Exclusive intramural squamous cell carcinoma with normal overlying mucosa is an exceedingly rare presentation of primary ESCC with only four cases reported in the literature so far. A high index of suspicion is required by the gastroenterologists and pathologists in diagnosing these cases as these tumors closely mimic the mesenchymal submucosal tumors such as lipoma, leiomyoma, and gastrointestinal stromal tumors. EUS is an indispensable tool in making a preoperative diagnosis and therapeutic decision making.

Quantification of Esophageal Tumor Motion and Investigation of Different Image-Guided Correction Strategies

2020 ◽  
Vol 10 (2) ◽  
pp. 84-92 ◽  
Author(s):  
Francine E.M. Voncken ◽  
Sareh Nakhaee ◽  
Barbara Stam ◽  
Lisa Wiersema ◽  
Sophie E. Vollenbrock ◽  
...  
Keyword(s):  
Esophageal Tumor ◽  
Tumor Motion ◽  
Image Guided ◽  
Correction Strategies

PS02.186: EUS-GUIDED FIDUCIAL MARKER INSERTION TO GUIDE RADIOTHERAPY IN ADVANCED ESOPHAGEAL CARCINOMA.

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 174-175
Author(s):  
Shannon Chan ◽  
Anthony Teoh ◽  
Hon Chi Yip ◽  
Vivien Wong ◽  
Philip Chiu ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Tumor Response ◽  
Conflicts Of Interest ◽  
Concurrent Chemotherapy ◽  
Fiducial Marker ◽  
Esophageal Tumor ◽  
Fiducial Markers ◽  
Migration Rates ◽  
The Mean ◽  
Esophageal Carcinomas

Abstract Background The use of radiotherapy with or without concurrent chemotherapy is frequently required in treatment of advanced esophageal carcinomas. It can be given in an adjuvant, neoadjuvant or definitive setting. However, the margins of the tumor are often difficult to ascertain on computed tomography. Thus, EUS-guided fiducial marker insertion has an important role to aid the localization of the proximal and distal margins of the esophageal tumor. However, the optimal technique of the procedure is still uncertain. Methods This was a retrospective study of all patients who received EUS-guided fiducial marker insertion between March 2015 and October 2017. All patients suffering from esophageal carcinoma scheduled for radiotherapy underwent the procedure within one week of the scheduled appointment. Gold fiducial markers 5mm x 0.35mm (Visicoil, IBA Dosimetry, USA) were back loaded onto a 22-gauge needle (Vizishot, Olympus Medical, Japan) or (Expect, Boston Scientific, USA). The markers were placed under EUS guidance either intratumorally or in the normal submucosa just proximal and distal to the tumor.The submucosal planes were raised with diluted hyaluronic acid before insertion of the marker. Outcome parameters included tumor characteristics, early and late migration rates and tumor response rates. Results 35 patients were included in the study. The mean (S.D.) age was 61.0 (9.9) years old. The mean (S.D.) length of the tumor were 7.2 (6.0) cm and and 86.2% of the patients had stage 3 disease. 27 patients had markers inserted by EBUS and 71.4% in the submucosa. When comparing fiducials that were placed in the submucosa versus intratumorally, significantly more fiducials had early (30% vs 0%, P = 0.004) and late migration (80% vs 0%, P < 0.001) in the intratumoral group. There were no differences in the stage of disease (P = 0.870), percentage of patients that completed radiotherapy (P = 0.063) and response rate (P = 0.197). There were no adverse effects in both groups. Conclusion In esophageal carcinomas planned for radiotherapy, EUS-guided fiducial markers should be placed in the submucosa just proximal and distal to the tumor instead of intratumorally. This may be able to increase the precision for radiotherapy. Disclosure All authors have declared no conflicts of interest.

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