scholarly journals A Rare Case of Statin-Induced Diplopia: An Often-Overlooked but Reported Side Effect

Cureus ◽  
2021 ◽  
Author(s):  
Randa Abdelmasih ◽  
Ramy Abdelmaseih ◽  
Justin Reed
Keyword(s):  
Side Effect ◽  
Rare Case

scholarly journals Ocular side effect of tinidazole: A rare case report

2014 ◽  
Vol 3 (4) ◽  
pp. 467
Author(s):  
Hina Kauser ◽  
Maniah Qadir ◽  
Waseem Anwar
Keyword(s):  
Case Report ◽  
Side Effect ◽  
Rare Case ◽  
Ocular Side ◽  
Rare Case Report ◽  
Ocular Side Effect

scholarly journals A Rare Case of Ethambutol Induced Optic Neuritis in a Peripheral Health Institute of Northern India

2021 ◽  
Vol 6 (2) ◽  
pp. 14-16
Author(s):  
Vatsayan Rahul ◽  
Sharma Deeksha
Keyword(s):  
Optic Neuritis ◽  
Side Effect ◽  
Rare Case ◽  
Clinical Presentation ◽  
Complete Recovery ◽  
Prevention Strategies ◽  
First Line ◽  
Therapy Discontinuation ◽  
Northern India ◽  
Rare Side Effect

Ethambutol (EMB) is one of the first-line drugs in the treatment of tuberculosis. EMB induces ocular toxicity which is a rare side-effect that is either dose-related or duration-related effect and is often reversible on therapy discontinuation. The toxicity has been reported at 4 to 12 months of the initiation of the therapy. We reported a rare case of EMB-induced optic neuritis after 1 month of initiation of the therapy. After the withdrawal of the drug, there was complete recovery of the patient. This case description would improve the understanding of the clinical presentation as well as the treatment of ethambutol optic neuritis, especially in recourse-limited settings. It would also enrich the knowledge regarding the prevention strategies and timely recognition of the side effect. Keywords: Ethambutol, Optic neuritis, Isoniazid.

Septic arthritis caused by Candida albicans: post intra-articular steroid injection in a native joint

2020 ◽  
Vol 13 (8) ◽  
pp. e233841 ◽  
Author(s):  
Siok Li Chung ◽  
Joseph Papanikitas ◽  
David Johnstone ◽  
David McKean
Keyword(s):  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Septic Arthritis ◽  
Side Effect ◽  
Rare Case ◽  
Neonatal Period ◽  
Steroid Injection ◽  
Physiotherapy Treatment ◽  
Steroid Injections ◽  
Micro Organisms

Intra-articular steroid injections are widely prescribed for management of osteoarthritis when oral medication or physiotherapy treatment fails to relieve patient’s pain. Septic arthritis is an uncommon side effect of steroid injection. Common causal micro-organisms are bacterial with Staphylococcus aureus being the most frequent. Fungal septic arthritis is rare and does not usually present beyond the neonatal period. We present a rare case of septic arthritis secondary to fungal infection.

scholarly journals A Case Report On Fluoro-Quinolones (Ofloxacin) Induced Psychosis At Nepal Medical College Teaching Hospital

2019 ◽  
Vol 8 (2) ◽  
pp. 66-67
Author(s):  
S. Khadka ◽  
P.M. Singh ◽  
M. Khadka ◽  
K. Chakrabarti ◽  
S. Pandit ◽  
...  
Keyword(s):  
Case Report ◽  
Mental Disorder ◽  
Side Effect ◽  
Psychiatric Illness ◽  
Rare Case ◽  
Affective Response ◽  
College Teaching ◽  
History Taking ◽  
Detailed History ◽  
Medical College

Psychosis is a mental disorder in which the thoughts, affective response, ability to recognise reality and ability to communicate and relate to others are significantly impaired to interfere grossly with the capacity to deal with the reality. Psychosis can also occur as a side effect of some type of drugs and may be misdiagnosed as psychiatric illness. We report a rare case of 30 years old female admitted to Nepal Medical College with hallucinations and delusions following ofloxacin use, by extensive / detailed history taking.

scholarly journals When Your Pituitary Fails - A Rare Case of Pituitary Dysfunction Due to Nivolumab and Ipilimumab

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A620-A621
Author(s):  
Areej Khan ◽  
Muhammad Ahmed Khan ◽  
Brian Phillips
Keyword(s):  
Adrenal Insufficiency ◽  
Side Effect ◽  
Rare Case ◽  
Case Description ◽  
Acth Level ◽  
Significant Side Effect ◽  
Pituitary Dysfunction ◽  
Rare Side Effect ◽  
History Of ◽  
Persistent Hypotension

Abstract Introduction: Immunomodulators like Nivolumab and Ipilimumab are important regimens in many malignancies. However, their use is linked with the rare side effect of pituitary dysfunction that if screened and treated can prevent misdiagnosis. Case Description: A 56-year-old male with a history of renal cell carcinoma status post bilateral partial nephrectomy with metastasis to the lung on Nivolumab/Ipilimumab presented with dizziness. He endorsed difficulty with balance, nausea, decreased appetite, feeling dehydrated and recent blood pressure readings in the 90s. Vitals on presentation were stable. An MRI, from 2 weeks ago, showed a slightly enlarged sella but no metastatic disease. The next day, he became hypotensive with minimal response to fluids and was started on Midodrine. However, considering his persistent hypotension, his cortisol level was checked and found to be profoundly low (<1). Literature review of his immunomodulator revealed the possibility of central adrenal insufficiency. In addition, he was noted to have a low TSH (0.02) with normal FT4 (1.08). Subsequently, his ACTH level was also found to be low (<1.5) which further elucidated a central cause for his adrenal insufficiency. Therefore, he was ultimately treated with PO hydrocortisone with plans to taper off in the next few weeks. Conclusion: This case demonstrates a rare yet significant side effect of Nivolumab/Ipilimumab therapy. Timely diagnosis and therapy can alleviate symptoms due to associated hormonal deficiencies. Moving forward it will be interesting to see if starting prophylactic steroids or routine screening will allow us to diagnose pituitary dysfunction due to Nivolumab/Ipilimumab earlier.

scholarly journals A rare case of neomercazole induced hepatitis

2018 ◽  
Vol 6 (5) ◽  
pp. 1812
Author(s):  
Muralidhar Varma ◽  
Jaikaran Mansingh ◽  
Devyani Sivakumar ◽  
Rabia Dhalla ◽  
Sudha Vidyasagar ◽  
...  
Keyword(s):  
Side Effects ◽  
Liver Function ◽  
Hair Loss ◽  
Side Effect ◽  
Rare Case ◽  
Antithyroid Drug ◽  
Disease Diagnosis ◽  
The Other ◽  
Common Side Effect ◽  
Graves Disease

Neomercazole is one of the most commonly used drugs to treat hyperthyroidism. Common side effects include rash, hair loss and agranulocytosis. Hepatotoxicity is a common side effect of Propylthiouracil, the other major antithyroid drug, but it has been rarely described as a side effect of neomercazole. Here, a patient presents with hepatitis 6 months after starting neomercazole therapy for graves disease. Diagnosis is based on excluding other causes of hepatitis, and treatment involves removing the offending drug. This is followed by normalization of liver function. Rechallenging should not be done as it can lead to recurrence of symptoms.

scholarly journals Vitiligo-Like Depigmentation following Treatment with Imiquimod 5% Cream for Condylomata Acuminata

2021 ◽  
pp. 36-41
Author(s):  
Maram Alatabani ◽  
Yasser Ghobara ◽  
Ahmed Alissa
Keyword(s):  
Side Effect ◽  
Rare Case ◽  
Condylomata Acuminata ◽  
Genital Warts ◽  
Healthy Male ◽  
Anogenital Warts ◽  
Imiquimod Cream ◽  
Human Melanocyte ◽  
The Us ◽  
Antigen Presenting

Imiquimod cream is an immunomodulatory agent that has been approved by the US Food and Drug Administration for use in the treatment of anogenital warts (condylomata acuminata) due to its local immune effects in activating Toll-like receptors 7 and 8 on antigen-presenting cells, resulting in reduction of the viral load of human papillomavirus with subsequent wart regression. After its application, some side effects are commonly reported, including erythema, edema, scaling, erosion, and ulceration. While pigmentary changes, including vitiligo-like depigmentation, have been mentioned as a possible side effect, they have rarely been reported in the literature. Alterations in pigmentation occur because imiquimod application causes human melanocyte apoptosis and autodestruction resulting in loss of melanocytes. Herein, we report the rare case of a 34-year-old healthy male who developed vitiligo-like depigmentation following imiquimod application for his genital warts. This case report aims to increase physicians’ awareness of this possible side effect that could be irreversible and difficult for the patient to accept.

Identification of Pulmonary Deposits from a Sandpaper Worker: A Study by Electron Microscopy and X-Ray Microanalysis

1982 ◽  
Vol 40 ◽  
pp. 52-53
Author(s):  
S. K. Peng ◽  
M.A. Egy ◽  
J. K. Singh ◽  
M.B. Bishop
Keyword(s):  
Electron Microscopy ◽  
Environmental Pollution ◽  
Rare Case ◽  
Interstitial Fibrosis ◽  
X Ray ◽  
Documented Case ◽  
Etiologic Agents ◽  
Pulmonary Interstitial Fibrosis ◽  
Gold Miners ◽  
Pulmonary Changes

Electron microscopy and energy dispersive x-ray microanalysis (EDXA) are found to be very useful tools for identification of etiologic agents in pneumoconiosis or interstitial pulmonary disorders. Pulmonary interstitial fibrosis and granulomatosis are frequently associated with occupational and environmental pollution. Numerous reports of pneumoconiosis in various occupations such as coal and gold miners are presented in the literature. However, there is no known documented case of pulmonary changes in workers in the sandpaper industry. This study reports a rare case of pulmonary granulomatosis containing deposits from abrasives of sandpaper diagnosed by using EDXA.

Conjunctival oedema: a side-effect of cyclosporin toxicity and a consequence of obesity

1996 ◽  
Vol 135 (1) ◽  
pp. 146-147 ◽  
Author(s):  
E. Papadavid ◽  
J. Yell ◽  
T.J. Ryan
Keyword(s):  
Side Effect
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