scholarly journals Serum Levels of OX40 in Early and Late-Stage Oral Squamous Cell Carcinoma

Cureus ◽  
2021 ◽  
Author(s):  
Aliya I Sani ◽  
Zil E Rubab ◽  
Shumaila Usman ◽  
Syed Zaryab Ahmed ◽  
Mervyn Hosein ◽  
...  
2020 ◽  
Vol 6 (4) ◽  
pp. 428-432
Author(s):  
Samuel E. Udeabor ◽  
Abdullah M. Albejadi ◽  
Waleed A. K. Al‐Shehri ◽  
Chidozie I. Onwuka ◽  
Saeed Y. Al‐Fathani ◽  
...  

Tumor Biology ◽  
2013 ◽  
Vol 35 (4) ◽  
pp. 3827-3829 ◽  
Author(s):  
Maryam Mardani ◽  
Azadeh Andisheh-Tadbir ◽  
Bijan Khademi ◽  
Mohammad Javad Fattahi ◽  
Shapour Shafiee ◽  
...  

2016 ◽  
Vol 46 (7) ◽  
pp. 489-495 ◽  
Author(s):  
Guy R. Adami ◽  
Thomas N. O'Callaghan ◽  
Antonia Kolokythas ◽  
Robert. J. Cabay ◽  
Yalu Zhou ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (14) ◽  
pp. e3149 ◽  
Author(s):  
Mohamad Adel ◽  
Chung-Kan Tsao ◽  
Fu-Chan Wei ◽  
Huei-Tzu Chien ◽  
Chih-Hsiung Lai ◽  
...  

2015 ◽  
Vol 16 (4) ◽  
pp. 1327-1330 ◽  
Author(s):  
Alireza Lotfi ◽  
Ghodrat Mohammadi ◽  
Atena Tavassoli ◽  
Mehrnoosh mousaviagdas ◽  
Hadi Chavoshi ◽  
...  

2016 ◽  
Vol 4 (1) ◽  
pp. 18 ◽  
Author(s):  
Bhavana Agrawal ◽  
R N Mody ◽  
Arun Tadas

Aim: To estimate and compare serum β2-microglobulin levels in oral leukoplakia and oral squamous cell carcinoma patients with that of control group.Material and Methods: The study was carried out on 70 subjects divided into three groups (20 oral leukoplakia patients, 30 oral squamous cell carcinoma patients and 20 controls). Serum β2-microglobulin was estimated by an enzyme linked immunosorbent assay (ELISA).Results: A significant increase in serum levels of β2-microglobulin was observed in oral squamous cell carcinoma patients as compared to control group.Conclusions: Results of this study suggest that estimation of serum β2-microglobulin can be useful in as biomarker for diagnosis of oral squamous cell carcinoma.


2019 ◽  
Vol 35 (1) ◽  
Author(s):  
Nakhshab Choudhry ◽  
Sana Sarmad ◽  
Noor Ul Ain Waheed ◽  
Aamir Jamal Gondal

Objective: To estimate the serum levels of matrix metalloproteinases in oral squamous cell carcinoma patients and in healthy subjects. Methods: In this observational study, biopsy diagnosed oral squamous cell carcinoma patients (n= 38) were recruited from Mayo Hospital, Lahore during 2016 to 2017. Age and gender matched Controls (n= 38) were also included. Venous blood sample of each participant was drawn, serum separated and the levels of matrix metalloproteinases were measured by multiplex ELISA. Results: Serum levels of MMP-1, -8, -10, -12 and -13 in OSCC patients showed statistically significant increase as compared to control group (p < 0.01). The MMP-12 predicted the presence of OSCC with highest AUC of 0.836 (95% CI [0.733 to 0.911]) for sensitivity and specificity of 80% and 78.9%, respectively for a cut-off value of 16.13 pg/ml. Conclusions: MMP-12 has been found to have significant sensitivity and specificity to qualify as a diagnostic biomarker. How to cite this:Choudhry N, Sarmad S, Waheed NA, Gondal AJ. Estimation of serum matrix metalloproteinases among patients of oral squamous cell carcinoma. Pak J Med Sci. 2019;35(1):252-256. doi: https://doi.org/doi.org/10.12669/pjms.35.1.68 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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