scholarly journals Diagnostic Accuracy of Intraoperative Touch Imprint Cytology for the Diagnosis of Axillary Sentinel Lymph Node Metastasis of Breast Cancer: Comparison With Intraoperative Frozen Section Evaluation

Cureus ◽  
2021 ◽  
Author(s):  
Atif A Hashmi ◽  
Samreen Naz ◽  
Omer Ahmed ◽  
Syed Rafay Yaqeen ◽  
Anoshia Afzal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Metastasis ◽  
Diagnostic Accuracy ◽  
Frozen Section ◽  
Imprint Cytology ◽  
Node Metastasis ◽  
Touch Imprint Cytology ◽  
Section Evaluation

scholarly journals Intraoperative imprint cytology of sentinel lymph nodes in breast cancer patients: Comparation with frozen section

2020 ◽  
Vol 77 (2) ◽  
pp. 196-200
Author(s):  
Tatjana Ivkovic-Kapicl ◽  
Ferenc Vicko ◽  
Milana Panjkovic ◽  
Zoran Radovanovic ◽  
Tijana Vasiljevic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Nodes ◽  
Cancer Patients ◽  
Frozen Section ◽  
Sentinel Lymph Nodes ◽  
Imprint Cytology ◽  
Breast Cancer Patients ◽  
Touch Imprint Cytology

Background/Aim. Sentinel lymph node (SLN) biopsy has been established as the standard of care for axillary staging in patients with invasive breast carcinoma and clinically negative lymph nodes. Intraoperative assessment of sentinel lymph nodes might be done by frozen section (FS), touch imprint cytology (TIC) and one step nucleic acid amplification. The aim of this study was to review our institution's results with SLN biopsy using TIC and FS technique as intraoperative diagnostic tool for breast cancer patients. Methods. SLNs from 101 patients were examined intraoperatively by frozen hematoxylin-eosin (H&E) stain and by touch imprint cytology. Results of TIC were compared with FS and permanent histology sections. Results. The total number of dissected SLNs was 163 with a mean of 1.6 (1?4) per patient. The permanent H&E identified 19 (19%) patients with a sentinel lymph node metastasis and 82 (81%) patients with tumor-free sentinel nodes. The sensitivity/ specificity rates were 73.7%/99.3%, respectively for TIC and 84.2%/100%, respectively for FS. Relevant positive/ negative predictive values were 93.3%/96.6%, respectively for TIC and 100%/97.9%, respectively for FS. Conclusion. Our experience with TIC and FS for the intraoperative evaluation of SLNs is similar to the findings from previously reported studies. We detected the high specificity for both methods, but TIC technique appeared to be less sensitive than FS in detecting SLN metastases in breast cancer patients. TIC could be recommended as reasonable alternative to frozen section due to its simplicity and low cost.

scholarly journals Imprint cytology versus frozen section analysis for intraoperative assessment of sentinel lymph node in breast cancer

2017 ◽  
Vol Volume 9 ◽  
pp. 325-330 ◽  
Author(s):  
Thalia Petropoulou ◽  
Antonia Kapoula ◽  
Aikaterini Mastoraki ◽  
Aikaterini Politi ◽  
Eleni Spanidou-Karvouni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Frozen Section ◽  
Imprint Cytology ◽  
Intraoperative Assessment ◽  
Frozen Section Analysis ◽  
Section Analysis

scholarly journals Targeted axillary dissection in breast cancer by marking lymph node metastasis with a magnetic seed before starting neoadjuvant treatment

2019 ◽  
Vol 2019 (11) ◽  
Author(s):  
Joaquín Luis García-Moreno ◽  
Ana María Benjumeda-Gonzalez ◽  
Marta Amerigo-Góngora ◽  
Piero José Landra-Dulanto ◽  
Yisela Gonzalez-Corena ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Metastasis ◽  
Axillary Dissection ◽  
Neoadjuvant Treatment ◽  
Axillary Lymph Node Metastasis ◽  
Axillary Lymph ◽  
Node Metastasis ◽  
Magnetic Seeds

Abstract We report the first documented clinical case of the use of magnetic seeds to mark axillary lymph node metastasis in breast cancer before neoadjuvant chemotherapy. After chemotherapy, the patient showed a complete radiological response. One single sentinel lymph node was detected using a radiotracer, while the marked node was intraoperative magnetometer-guided identified. The analysis of the nodes showed negative sentinel lymph node and positive marked node, and the subsequent targeted axillary dissection was performed. Marking axillary positive lymph nodes with a magnetic seed is a simple and effective procedure for the intraoperative localisation of the node after neoadjuvant treatment.

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