scholarly journals High Dose Gamma Radiation Selectively Reduces GABAA-slow Inhibition

Cureus ◽  
2017 ◽  
Author(s):  
Beza A Dagne ◽  
Melis K Sunay ◽  
Noëlie S Cayla ◽  
Yi-Bing Ouyang ◽  
Susan J Knox ◽  
...  
Keyword(s):  
2005 ◽  
Vol 68 (12) ◽  
pp. 2571-2579 ◽  
Author(s):  
STÉPHANE CAILLET ◽  
FRANÇOIS SHARECK ◽  
MONIQUE LACROIX

This study was carried out to evaluate the effects of gamma radiation alone or in combination with oregano essential oil on the murein composition of Escherichia coli O157:H7 and on the intracellular and extracellular concentrations of ATP. The bacterial strain was treated with three radiation doses: 0.4 kGy to induce cell damage, 1.1 kGy to obtain a viable but nonculturable state, and 1.3 kGy to cause cell death. Oregano essential oil was used at 0.006 and 0.025% (wt/vol), which is the MIC. All treatments had a significant effect (P ≤ 0.05) on the murein composition, although some muropeptides did not seem to be affected by the treatment. Each treatment had a different effect on the relative percentage and number of muropeptides. There was a significant correlation (P ≤ 0.05) between the decrease in intracellular ATP and the increase in extracellular ATP following treatment of the cells with oregano oil. The reduction of intracellular ATP was even more important when oregano oil was combined with irradiation, but irradiation alone at a high dose (≤1.1 kGy) significantly decreased (P ≤ 0.05) the internal ATP without affecting the external ATP. Transmission electron microscopic examination revealed that oregano oil and irradiation have an effect on cell wall structure.


2004 ◽  
Vol 1 (3) ◽  
pp. 358
Author(s):  
Anirban K. Mitra ◽  
Rakesh K. Singh ◽  
Himanshi Narang ◽  
M. Krishna ◽  
Sanjeev K. Maurya

2008 ◽  
Vol 43 (2-6) ◽  
pp. 1160-1162 ◽  
Author(s):  
F. Camargo ◽  
J.A.C. Gonçalves ◽  
H.J. Khoury ◽  
C.M. Napolitano ◽  
J. Härkönen ◽  
...  
Keyword(s):  

1998 ◽  
Vol 149 (5) ◽  
pp. 472 ◽  
Author(s):  
C. Geffrotin ◽  
Y. Tricaud ◽  
F. Crechet ◽  
M. Castelli ◽  
J-L. Lefaix ◽  
...  

2006 ◽  
Author(s):  
Marco Van Uffelen ◽  
Yehia El Shazly ◽  
Stephen Kukureka ◽  
Gerard Kuyt ◽  
Elise Regnier ◽  
...  

2018 ◽  
Vol 22 ◽  
pp. 28-33
Author(s):  
O. Yu. German

Aim. To study the possibility of bystander effect inducing in the joint germination in a common aqueous environment of irradiated and non-irradiated seeds. Methods. Cytogenetic methods including mitotic activity level estimation, accounting for the number of nucleoli, and methods for statistical analysis of the data. Results. The effect of radiation stimulation with a dose of 40 Gy was dependent on the variety, and the effect of gamma radiation at a dose of 200 Gy reduced the level of mitotic activity in comparison with the control in both varieties. Mitotic indices increase in the meristem of non-irradiated seeds while growing with irradiated one. Conclusions. The bystander effect is formed on the organismic level under condition of growing of irradiated and non-irradiated seeds in a common aquatic environment and it is ma-nifested as an increase in the level of meristem cells proliferation and in the intensification of synthetic processes. The addition of irradiated with a high dose of gamma radiation seeds to the non-irradiated seeds induces an increase in mitotic activity largely than the addition of seeds irradiated with a relatively small dose. Keywords: bystander effect, radiation stimulation, mitotic activity, nucleoli.


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