scholarly journals Successful Lumpectomy in a Patient With Multicentric Breast Cancer

Cureus ◽  
2020 ◽  
Author(s):  
Quan D Nguyen ◽  
Anahita Tavana ◽  
Sarfaraz Sadruddin ◽  
Celia Chao
Keyword(s):  
Breast Cancer ◽  
Multicentric Breast Cancer

scholarly journals Extreme Oncoplasty: Breast Conservation in Patients with Large, Multifocal, and Multicentric Breast Cancer

2021 ◽  
Vol Volume 13 ◽  
pp. 353-359
Author(s):  
Francesca Savioli ◽  
Subodh Seth ◽  
Elizabeth Morrow ◽  
Julie Doughty ◽  
Sheila Stallard ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Multicentric Breast Cancer

scholarly journals Multifocal and multicentric breast cancer, is it time to think again?

2020 ◽  
Vol 102 (1) ◽  
pp. 62-66 ◽  
Author(s):  
YA Masannat ◽  
A Agrawal ◽  
L Maraqa ◽  
M Fuller ◽  
SK Down ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Breast Conserving Surgery ◽  
Disease Recurrence ◽  
Locoregional Control ◽  
Current Evidence ◽  
Multicentric Breast Cancer ◽  
Risk Of Disease ◽  
Short Narrative

Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many breast surgeons are advocating breast conservation in selected cases. This short narrative review summarises current evidence on the role of surgery in multifocal multicentric breast cancer and shows that when technically feasible the option of breast conservation is oncologically safe.

Multicentric Breast Cancer: A New Indication for Sentinel Node Biopsy—A Multi-Institutional Validation Study

2006 ◽  
Vol 24 (21) ◽  
pp. 3374-3380 ◽  
Author(s):  
Michael Knauer ◽  
Peter Konstantiniuk ◽  
Anton Haid ◽  
Etienne Wenzl ◽  
Michaela Riegler-Keil ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sentinel Node ◽  
False Negative ◽  
False Negative Rate ◽  
Breast Conserving Surgery ◽  
Axillary Lymph ◽  
Identification Rate ◽  
Multicentric Breast Cancer ◽  
Adequate Quality

Purpose Multicentric breast cancer has been considered to be a contraindication for sentinel node (SN) biopsy (SNB). In this prospective multi-institutional trial, SNB-feasibility and accuracy was evaluated in 142 patients with multicentric cancer from the Austrian Sentinel Node Study Group (ASNSG) and compared with data from 3,216 patients with unicentric cancer. Patients and Methods Between 1996 and 2004, 3,730 patients underwent SNB at 15 ASNSG-affiliated hospitals. Patient data were entered in a multicenter database. One hundred forty-two patients presented with multicentric invasive breast cancer and underwent SNB. Results Intraoperatively, a mean number of 1.67 SNs were excised (identification-rate, 91.5%). The incidence of SN metastases was 60.8% (79 of 130). This was confirmed by axillary lymph node dissection (ALND) in 125 patients. Of patients with positive SNs, 60.8% (48 of 79) showed involvement of nonsentinel nodes (NSNs), as did three patients with negative SNs (false-negative rate, 4.0). Sensitivity, negative predictive value, and overall accuracy were 96.0%, 93.3%, and 97.3%, respectively. Ninety-one percent of the patients underwent mastectomy, and 9% were treated with breast conserving surgery. None of the patients have shown axillary recurrence so far (mean follow-up, 28.8 months). Compared with 3,216 patients with unicentric cancer, there was a significantly higher rate of SN metastases as well as in NSNs, whereas there was no difference in detection and false-negative rates. Conclusion Multicentric breast cancer is a new indication for SNB without routine ALND in controlled trials. Given adequate quality control and an interdisciplinary teamwork of surgical, nuclear medicine, and pathology units, SNB is both feasible and accurate in this disease entity.

Prognostic impact of multifocal and multicentric breast cancer compared with unifocal breast cancer.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e12614-e12614
Author(s):  
Atsushi Fushimi ◽  
Atsushi Yoshida ◽  
Hiroshi Yagata ◽  
Osamu Takahashi ◽  
Naoki Hayashi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Impact ◽  
Multicentric Breast Cancer

Sentinel Node Biopsy in Patients with Multicentric Breast Cancer using a Subareolar Injection Technique

2002 ◽  
Vol 34 (5) ◽  
pp. 288-291 ◽  
Author(s):  
P. Schrenk ◽  
Soraya Wolfl ◽  
Ch. Tausch ◽  
Claudia Mauritz ◽  
P. Konstantiniuk ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Injection Technique ◽  
Subareolar Injection ◽  
Node Biopsy ◽  
Multicentric Breast Cancer

Indications for sentinel lymph node biopsy in multifocal and multicentric breast cancer

Surgery ◽  
2012 ◽  
Vol 152 (3) ◽  
pp. 389-396 ◽  
Author(s):  
Lisa C. Moody ◽  
Xianfeng Wen ◽  
Teckshell McKnight ◽  
Celia Chao
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Multicentric Breast Cancer
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