scholarly journals Extreme Oncoplasty: Breast Conservation in Patients with Large, Multifocal, and Multicentric Breast Cancer

2021 ◽  
Vol Volume 13 ◽  
pp. 353-359
Author(s):  
Francesca Savioli ◽  
Subodh Seth ◽  
Elizabeth Morrow ◽  
Julie Doughty ◽  
Sheila Stallard ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Multicentric Breast Cancer

scholarly journals Multifocal and multicentric breast cancer, is it time to think again?

2020 ◽  
Vol 102 (1) ◽  
pp. 62-66 ◽  
Author(s):  
YA Masannat ◽  
A Agrawal ◽  
L Maraqa ◽  
M Fuller ◽  
SK Down ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Breast Conserving Surgery ◽  
Disease Recurrence ◽  
Locoregional Control ◽  
Current Evidence ◽  
Multicentric Breast Cancer ◽  
Risk Of Disease ◽  
Short Narrative

Multifocal multicentric breast cancer has traditionally been considered a contraindication to breast conserving surgery because of concerns regarding locoregional control and risk of disease recurrence. However, the evidence supporting this practice is limited. Increasingly, many breast surgeons are advocating breast conservation in selected cases. This short narrative review summarises current evidence on the role of surgery in multifocal multicentric breast cancer and shows that when technically feasible the option of breast conservation is oncologically safe.

Breast Conservation in Women with Multifocal-Multicentric Breast Cancer: Is It Feasible?

2010 ◽  
Vol 17 (S3) ◽  
pp. 325-329 ◽  
Author(s):  
Laura Bauman ◽  
Richard J. Barth ◽  
Kari M. Rosenkranz
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Multicentric Breast Cancer

scholarly journals Breast Conservation Surgery: State of the Art

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Jonathan White ◽  
Raj Achuthan ◽  
Philip Turton ◽  
Mark Lansdown
Keyword(s):  
Breast Cancer ◽  
Breast Conservation ◽  
Surgical Techniques ◽  
Breast Conservation Surgery ◽  
Breast Size ◽  
Conservation Surgery ◽  
Multicentric Breast Cancer ◽  
The Relationship ◽  
Endoscopic Breast Surgery

Breast conservation surgery is available to the vast majority of women with breast cancer. The combination of neoadjuvant therapies and oncoplastic surgical techniques allows even large tumours to be managed with a breast-conserving approach. The relationship between breast size and the volume of tissue to be excised determines the need for volume displacement or replacement. Such an approach can also be used in the management of carefully selected cases of multifocal or multicentric breast cancer. The role of novel techniques, such as endoscopic breast surgery and radiofrequency ablation, is yet to be precisely defined.

Preliminary Results: Double Lumpectomies for Multicentric Breast Carcinoma

2012 ◽  
Vol 78 (12) ◽  
pp. 1345-1348 ◽  
Author(s):  
Nimmi S. Kapoor ◽  
Alice Chung ◽  
Kelly Huynh ◽  
Armando E. Giuliano
Keyword(s):  
Breast Cancer ◽  
Breast Carcinoma ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Breast Conservation ◽  
Breast Conserving Surgery ◽  
Second Malignancies ◽  
Small Series ◽  
Number Of Patients ◽  
Multicentric Breast Cancer

The standard operation for patients with multicentric breast cancer is total mastectomy. The safety of breast-conserving surgery (BCS) for these patients is unknown but interest in BCS has recently resurfaced as a result of the detection of occult second malignancies by breast magnetic resonance imaging (MRI). We report a small number of patients who chose to undergo “double lumpectomies,” defined as two separate segmental mastectomies for primary cancers in different quadrants of the same breast. Patients with multicentric breast cancer surgically managed with double lumpectomies at our institute were identified retrospectively. Clinicopathologic features are described and outcomes reported. Seven patients underwent double lumpectomies for multicentric carcinoma. Median age was 69 years (range, 61 to 80 years). In five patients, MRI identified ipsilateral second malignancies. All patients had two foci of invasive carcinoma, all tumors expressed estrogen receptor, and none showed HER-2 overexpression. Tumor sizes ranged from 0.7 to 2.9 cm. Six patients had histologically distinct tumors in the same breast: five had one invasive lobular carcinoma (ILC) and one invasive ductal carcinoma (IDC), and one had classic ILC in one quadrant and pleomorphic ILC in another. One patient had two foci of IDC in separate quadrants. All patients had sentinel lymph node biopsies and none had nodal metastasis. Median follow-up was 26 months (range, 18 to 85 months). No patient developed locoregional recurrence. This small series suggests that “double lumpectomy” may be considered for multicentric invasive breast carcinoma in carefully selected patients with favorable tumors who desire breast conservation.

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