scholarly journals Retrospective correlation analysis of plasma Immunoglobulin G and clinical performance in CIDP

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6969 ◽  
Author(s):  
Lars Kjøbsted Markvardsen ◽  
Stine Bruun-Sørensen ◽  
Ingelise Christiansen ◽  
Henning Andersen
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Immunoglobulin G ◽  
Motor Performance ◽  
Medical Research Council ◽  
Clinical Performance ◽  
Chronic Inflammatory Demyelinating Polyneuropathy ◽  
Walk Test ◽  
Performance Skills ◽  
Isokinetic Muscle Strength

Background Chronic inflammatory demyelinating polyneuropathy (CIDP) can be successfully treated with immunoglobulin either intravenously (IVIG) or subcutaneously (SCIG). Measurement of plasma immunoglobulin G levels (P-IgG) and its correlation to clinical improvement has shown conflicting results. This study aims to clarify whether changes in P-IgG are related to clinical development in patients with CIDP treated with IVIG or SCIG. Methods Patients from five previous studies treated with either IVIG or SCIG with evaluation at baseline and re-evaluation after two or 10/12 weeks, respectively were included. At evaluation and re-evaluation, the following tests were done: combined isokinetic muscle strength (cIKS), grip strength, 9-hole-peg test (9-HPT), 40-meter-walk test (40-MWT), clinical examination of muscle strength score by the Medical Research Council (MRC) and measurement of plasma immunoglobulin G (P-IgG). Results Fifty-five patients were included in the IVIG group and 41 in the SCIG group. There was no correlation between the changes in P-IgG and cIKS in neither the IVIG group (r = 0.137, p = 0.32) nor the SCIG group (r =  − 0.048, p = 0.77). Similarly, no correlations could be demonstrated between P-IgG and grip strength, 9-HPT, 40-MWT or MRC. Conclusions In patients with CIDP receiving SCIG or IVIG, changes in P-IgG during treatment did not correlate with changes in muscle strength or other motor performance skills.

scholarly journals Determination of the relationship between the wrist isokinetic muscle strenght and the grip strength in tennis players aged between 12-14

2017 ◽  
Vol 5 (2_suppl2) ◽  
pp. 2325967117S0007
Author(s):  
Bihter Akınoğlu ◽  
Tuğba Kocahan ◽  
Necmiye Ün Yıldırım ◽  
Çağlar Soylu ◽  
Adnan Hasanoğlu
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Standing Position ◽  
Dominant Hand ◽  
Sitting Position ◽  
Wrist Flexion ◽  
Tennis Players ◽  
Isokinetic Muscle Strength ◽  
The Relationship ◽  
Flexion And Extension

Aim: The purpose of this study is to determine the relationship between isokinetic wrist muscle strenght and grip strength in tennis players aged between 12-14. Methods: This study was carried out with the participation of 9 (3 female and 6 male) tennis players aged between 12-14 (means 13,22±0,83). Weight, height, body mass index and dominant extremity of the players were recorded. İsokinetic measurement was performed with Isomed 2000® device. İsokinetic testing protocol; before the test all players performed the wrist flexion and extension isokinetic test with the 5 repeating at 90 º/sec as a warm-up and for comprehenting the test. Then, wrist flexion and extension concentric-concentric strength measurements were performed with the 5 repeating at 60 º/sec and with the 15 repeating at 240 º/sec with the angle between 50 degrees of wrist flexion and 60 degrees of wrist extension and peak torque values were recorded. Standard Jamar® Dynamometer was used for grip strength measurements. Grip strenght was performed firstly in sitting position, which is the position of standard measurement. Secondly, in standing position, the elbow was in full ekstansion and the forearm was in neutral position. Thirdly, in standing position the wrist was positioned approximately 30° extension and 10° ulnar deviation. This test was repeated 3 times in all test position and the mean of three scores were recorded. Firstly, the dominant hand, then the non-dominant hand was evoluated. They were allowed to rest for 30 seconds between each grip measurement. Correlation between peak tork of isokinetic muscle strenght and grip strength was done having been used Spearman correlation test. Findings: It was determined that there was a significant positive relation between wrist flexion-extension isokinetic muscle strength and grip strenght in tennis players aged between 12-14. Clinically, grip strength measured in the standard sitting position was found more as compared to the other positions but these values were not statistically significant (p>0,05). Accordingly, grip strength measured in the standard sitting position correlated with much more of the parameters which we evaluated for isokinetic muscle strength comparing to grip strenght measured in the other two positions (p<0,05). Results: It was concluded that isokinetic muscle strength of wrist can be affected by grip strength, therefore measurement needs to be done in the sitting position which maximum grip strength may reveal. [Table: see text]

scholarly journals Impact of peripheral muscle strength on prognosis after extubation and functional outcomes in critically ill patients: a feasibility study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tsung-Hsien Wang ◽  
Chin-Pyng Wu ◽  
Li-Ying Wang
Keyword(s):  
Muscle Strength ◽  
Hospital Mortality ◽  
Functional Outcomes ◽  
Extubation Failure ◽  
General Ward ◽  
Walk Test ◽  
Peripheral Muscle ◽  
Observational Cohort ◽  
Minute Walk ◽  
Overall Mortality

AbstractThe influence of peripheral muscle strength on prognosis after extubation and subsequent functional outcomes is not evident. The objectives of this study were to determine (1) whether peripheral muscle strength can be used as a predictor for patients’ prognoses after extubation, and (2) whether the peripheral muscle strength before extubation is correlated with patients’ subsequent ambulation ability and in-hospital mortality. This study was a prospective observational cohort study. A hand-held dynamometer was used for evaluated the muscle strength of the biceps and quadriceps right before extubation. Besides, after the patients had been transferred from the ICU to the general ward, a 2-minute walk test was performed. A total of 52 patients were enrolled in this study, and the rate of extubation failure was 15%. The muscle strength of the quadriceps was significantly correlated with the prognosis after extubation, 48% of the patients were able to ambulate after being transferred to the general ward. The overall mortality rate was 11%, and there was a significant correlation between the biceps muscle strength and in-hospital mortality. Peripheral muscle strength may serve as an important predictor of a patients’ prognoses after extubation. Poor peripheral muscle strength is indicative of not only a higher risk of re-intubation but also higher in-hospital mortality and poorer functional outcomes.Trial registration: ISRCTN16370134. Registered 30 May 2019, prospectively registered. https://www.isrctn.com/ISRCTN16370134.

scholarly journals Physical and functional performance assessment in pediatric oncology: a systematic review

2021 ◽  
Author(s):  
Regine Söntgerath ◽  
Julia Däggelmann ◽  
Sabine V. Kesting ◽  
Corina S. Rueegg ◽  
Torge-Christian Wittke ◽  
...  
Keyword(s):  
Systematic Review ◽  
Muscle Strength ◽  
Physical Performance ◽  
Cardiorespiratory Fitness ◽  
Pediatric Cancer ◽  
Motor Performance ◽  
Performance Test ◽  
Functional Mobility ◽  
Cancer Type ◽  
And Function

Abstract Background Research indicates reduced physical performance from diagnosis into survivorship of pediatric cancer patients. However, there is no systematic information or guideline available on the methods to assess physical performance and function in this population. The purpose was to systematically compile and describe assessments of physical performance and function in patients and survivors of pediatric cancer, including cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait and motor performance test batteries. Methods We searched the databases PubMed, SPORTDiscus, and Cochrane Database and performed abstract and full-text selection of 2619 articles according to the Cochrane Handbook of Systematic Reviews. Information on patients characteristics, assessments, information on validity and reliability, and relevant references was extracted. Results In summary, 63 different assessments were found in 149 studies including 11639 participants. Most studies evaluated cardiorespiratory fitness and muscle strength with the majority conducted off treatment. Some outcomes (e.g. speed) and diagnoses (e.g. neuroblastoma) were severely underrepresented. With the exception of gait, leukemia patients represented the largest group of individuals tested. Conclusions Insufficient data and patient heterogeneity complicate uniform recommendations for assessments. Our results support researchers and practitioners in selecting appropriate assessment to meet their specific research questions or individual daily practice needs. Impact This systematic review includes 149 studies and provides a comprehensive summary of 63 assessments to evaluate cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait or motor performance test batteries in patients and survivors of pediatric cancer. We present the most studied fields within the pediatric cancer population, which are cardiorespiratory fitness and muscle strength, off treatment phase, and leukemia patients. We propose research priorities by identification of subgroups in terms of cancer type, phase of treatment, and outcome of interest that are underrepresented in studies currently available.

The Effects of Tourniquet Application in Total Knee Arthroplasty on the Recovery of Thigh Muscle Strength and Clinical Outcomes

2020 ◽  
Author(s):  
Omer Ayik ◽  
Mehmet Demirel ◽  
Fevzi Birisik ◽  
Ali Ersen ◽  
Halil I. Balci ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Muscle Strength ◽  
Clinical Outcomes ◽  
Knee Arthroplasty ◽  
Peak Torque ◽  
Thigh Muscle ◽  
Controlled Study ◽  
Total Work ◽  
Isokinetic Muscle Strength ◽  
Total Knee

AbstractThe present randomized controlled study aims to evaluate whether tourniquet application during total knee arthroplasty (TKA) has an effect on (1) thigh muscle strength (quadriceps and hamstring muscle strength) and (2) clinical outcomes (postoperative knee range of motion [ROM], postoperative pain level, and Knee Society Score [KSS]). The effects of tourniquet application during TKA were investigated in 65 patients randomly allocated to one of two groups: TKA with a tourniquet and TKA without a tourniquet. Patients in both groups were comparable in terms of the demographic and clinical data (p > 0.05 for age, number of patients, sex, radiographic gonarthrosis grade, American Society of Anesthesiologists [ASA] classification, and body mass index [BMI]). All patients in both groups were operated by the same surgeon using one type of prosthesis. Isokinetic muscle strength (peak torque and total work) of knee extensors (quadriceps) and flexors (hamstrings) was measured in Newton meters (Nm) using a CYBEX 350 isokinetic dynamometer (HUMAC/CYBEX 2009, Stoughton, MA). The combined KSS (knee score + function score), visual analog scale (VAS), and knee ROM were measured preoperatively and at 1 and 3 months postoperatively to evaluate clinical outcomes. There were no significant differences between the two groups in preoperative and postoperative values of isokinetic muscle strength (peak torque and total work) and aforementioned clinical outcomes (p < 0.05). The present study has shown that quadriceps strength and clinical outcomes were not improved in the early postoperative period (3 months) when a tourniquet was not used during TKA.

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