scholarly journals Forensic characteristics and population genetics of Chinese Kazakh ethnic minority with an efficient STR panel

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6802
Author(s):  
Chong Chen ◽  
Yuxin Guo ◽  
Xiaoye Jin ◽  
Wei Cui ◽  
Yuanyuan Wei ◽  
...  
Keyword(s):  
Population Genetics ◽  
Ethnic Minority ◽  
Ethnic Group ◽  
Discrimination Performance ◽  
Genetic Distances ◽  
Healthy Individuals ◽  
Str Loci ◽  
Forensic Efficiency ◽  
Hardy Weinberg Equilibrium ◽  
Equilibrium Test

On the purpose of enhancing the forensic efficiency of CODIS STR loci, new STR loci have been gradually discovered and developed into some commercial multiplex systems. Recently, 22 STR loci including 18 non-CODIS STR loci and four CODIS STR loci were investigated in 501 unrelated healthy individuals of Kazakh ethnic group. Seven to 20 alleles at the different loci were identified and altogether 276 alleles for 22 selected loci were detected with the corresponding allelic frequencies ranging from 0.0010 to 0.3623. No significant deviation was observed from the Hardy–Weinberg equilibrium test for any of the 22 STRs. The value of cumulative power of discrimination in Kazakh group was 1-1.00E−28. Analyses of population differentiations and genetic distances between Kazakh and other Chinese groups presented that the Kazakh group with the Uygur group. These 22 STR loci evenly distributed on 22 different autosomal chromosomes were characterized by high genetic diversities and therefore could be utilized in the forensic cases to further increase the discrimination performance.

Population genetics study using 26 Y-chromosomal STR loci in the Hui ethnic group in China

2017 ◽  
Vol 28 ◽  
pp. e26-e27 ◽  
Author(s):  
Qi Zhao ◽  
Yingnan Bian ◽  
Suhua Zhang ◽  
Ruxin Zhu ◽  
Wei Zhou ◽  
...  
Keyword(s):  
Population Genetics ◽  
Ethnic Group ◽  
Str Loci

Population genetics and forensic efficiency of twenty-one novel microsatellite loci of Chinese Yi ethnic group

2013 ◽  
Vol 34 (24) ◽  
pp. 3345-3351 ◽  
Author(s):  
Bo-Feng Zhu ◽  
Feng Pan ◽  
Chun-Mei Shen ◽  
Jiang-Wei Yan ◽  
Hong-dan Wang ◽  
...  
Keyword(s):  
Population Genetics ◽  
Ethnic Group ◽  
Microsatellite Loci ◽  
Forensic Efficiency ◽  
Yi Ethnic Group

Population genetics for 17 Y-STR loci(AmpFISTR®Y-filerTM) in Luzhou Han ethnic group

2013 ◽  
Vol 7 (2) ◽  
pp. e23-e26 ◽  
Author(s):  
Long Bing ◽  
Weibo Liang ◽  
Jianhua Pi ◽  
Deming Zhang ◽  
Dai Yong ◽  
...  
Keyword(s):  
Population Genetics ◽  
Ethnic Group ◽  
Str Loci

scholarly journals Genetic polymorphisms and forensic efficiency of 19 X-chromosomal STR loci for Xinjiang Mongolian population

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5117 ◽  
Author(s):  
Ling Chen ◽  
Yuxin Guo ◽  
Cheng Xiao ◽  
Weibin Wu ◽  
Qiong Lan ◽  
...  
Keyword(s):  
Minority Group ◽  
Genetic Research ◽  
Bonferroni Correction ◽  
Significance Level ◽  
Autonomous Region ◽  
Str Loci ◽  
Asian Populations ◽  
Forensic Efficiency ◽  
Hardy Weinberg Equilibrium ◽  
High Utility

Aim X-chromosomal short tandem repeat (X-STR) loci are playing an increasingly important role in some complex kinship cases in recent years. To investigate the forensic efficiency of X-STRs of Mongolian minority group from Xinjiang Uygur Autonomous Region, China, and further depict the genetic relationship among Xinjiang Mongolians and other populations, 267 blood samples from unrelated healthy Xinjiang Mongolians were amplified by an AGCU X-19 STR kit. Results No deviations for all 19 X-STR loci were observed from the Hardy–Weinberg equilibrium after Bonferroni correction (p > 0.0026) in female samples. The most frequent allele was allele 10 at locus DXS10164 with the frequency 0.5663. The polymorphism information content values of the 19 X-STR loci were more than 0.5 with the highest polymorphism at the locus DXS10135. The cumulative power of discrimination were 0.99999999999999999999988761005481 in females and 0.999999999999903 in males, respectively; and the cumulative mean exclusion chances were 0.9999999969738068321121 in duos and 0.999999999998952 in trios, respectively. The seven linkage groups were extremely informative, with all the haplotype diversities greater than 0.9487. No linkage disequilibrium was observed for a significance level of 0.00029 (p = 0.05/171) after Bonferroni correction. The DA distances, multidimensional scaling plot and phylogenetic tree based on the 11 overlapping X-STR loci all presented that the Xinjiang Mongolian population was genetically different from other Asian populations, including the Mongolian population from Inner Mongolia Autonomous Region, China. Conclusion This study indicated that the 19 X-STR multiplex PCR system was of high utility value for both forensic practices and population genetic research in Xinjiang Mongolian group.

scholarly journals Genetic polymorphism of milk protein loci in Argentinian Holstein cattle

2000 ◽  
Vol 23 (4) ◽  
pp. 819-823 ◽  
Author(s):  
Adriana Gloria Bonvillani ◽  
Miguel Angel Di Renzo ◽  
Iván Nicolás Tiranti
Keyword(s):  
Genetic Polymorphism ◽  
Milk Protein ◽  
Genotypic Diversity ◽  
Genetic Distances ◽  
Holstein Cattle ◽  
Starch Gel Electrophoresis ◽  
Beta Casein ◽  
Hardy Weinberg Equilibrium ◽  
Quality Of Milk ◽  
Beta Lactoglobulin

Some alleles of milk protein loci are associated with superior cheese production characteristics. The genetic polymorphism of the milk protein loci alphas1-casein, beta-casein, k-casein and beta-lactoglobulin was examined in Argentinian Holstein cattle. Samples from 12 herds of four regions of Córdoba were analyzed by starch gel electrophoresis. The chi² test was used to assess whether the populations were in Hardy-Weinberg equilibrium. Genotypic diversity was analyzed by the Shannon-Weaver index. The observed genotypic frequencies were analyzed by Hedrick's genetic identity and the genetic distance of Balakrishnan and Sanghvi. The allelic and genotypic frequencies were similar to those of other Holstein populations. The genotypic frequencies of the alphas1-casein and beta-casein loci were in equilibrium, whereas in some populations the k-casein and beta-lactoglobulin loci were not. According to the Shannon-Weaver index the total genetic diversity within each herd was greater than 96%. The high values of identity agreed with the low genetic distances among populations. We conclude that there is extensive genetic homogeneity in Holstein cattle in Córdoba Province and that it would be feasible to select for B alleles at the k-casein and b-lactoglobulin loci in order to improve the quality of milk available for cheese manufacturing.

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