A Rare Case of Myonecrosis with Soft-Tissue Emphysema in a Diabetic Foot Caused by Streptococcus anginosus Isolated in Pure Culture: A Case Study

2019 ◽  
Vol 109 (4) ◽  
pp. 305-307
Author(s):  
Jack Route ◽  
Joseph Anain
Keyword(s):  
Soft Tissue ◽  
Rare Case ◽  
Infectious Agent ◽  
Human Pathogen ◽  
Streptococcus Anginosus ◽  
Streptococcus Milleri ◽  
Streptococcus Milleri Group ◽  
Soft Tissue Emphysema ◽  
Prevalent Pathogen

Streptococcus anginosus (SAG) is a known human pathogen and member of the Streptococcus milleri group. SAG is a known bacterial cause of soft-tissue abscesses and bacteremia and is an increasingly prevalent pathogen in infections in patients with cystic fibrosis. We describe a rare case of SAG as an infectious agent in a case of nonclostridial myonecrosis with soft-tissue emphysema. This is the only case found in the literature of SAG cultured as a pure isolate in this type of infection and was associated with a prolonged course of treatment in an otherwise healthy patient.

scholarly journals Necrotizing fasciitis caused by Pseudomonas aeruginosa: a rare case report and recent concepts in diagnosis and management

2020 ◽  
Vol 6 (5) ◽  
pp. 1100
Author(s):  
Naresh Kumar ◽  
Akshay Lamba ◽  
Jyotirmay Das ◽  
Avik K. Neogi ◽  
Kunal Arora ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Soft Tissue ◽  
Necrotizing Fasciitis ◽  
Rare Case ◽  
Functional Deficits ◽  
Rare Case Report ◽  
Life Threatening ◽  
Pseudomonas Infection ◽  
Early Debridement

<p>Necrotizing fasciitis caused by <em>Pseudomonas aeruginosa</em> is an extremely rare and life threatening bacterial soft tissue infection. Here we report a case study of fully established necrotizing fasciitis associated with monomicrobial pseudomonas infection in a 34 years old male. The patient presented with painful, necrosed areas of skin and soft tissue over right gluteal region which rapidly progressed to right upper back. Aggressive supportive measures and early debridement lead to a full recovery with no functional deficits.</p>

scholarly journals McKay agar enables routine quantification of the ‘Streptococcus milleri’ group in cystic fibrosis patients

2010 ◽  
Vol 59 (5) ◽  
pp. 534-540 ◽  
Author(s):  
Christopher D. Sibley ◽  
Margot E. Grinwis ◽  
Tyler R. Field ◽  
Michael D. Parkins ◽  
Jens C. Norgaard ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Clinical Laboratory ◽  
16S Rrna Gene Sequencing ◽  
Clinical Samples ◽  
Rrna Gene ◽  
Columbia Blood Agar ◽  
Streptococcus Anginosus ◽  
Streptococcus Milleri ◽  
Streptococcus Milleri Group ◽  
Rrna Gene Sequencing

The ‘Streptococcus milleri’ group (SMG) has recently been recognized as a contributor to bronchopulmonary disease in cystic fibrosis (CF). Routine detection and quantification is limited by current CF microbiology protocols. McKay agar was developed previously for the semi-selective isolation of this group. Here, McKay agar was validated against a panel of clinical SMG isolates, which revealed improved SMG recovery compared with Columbia blood agar. The effectiveness of this medium was evaluated by appending it to the standard CF sputum microbiology protocols in a clinical laboratory for a 6-month period. All unique colony types were isolated and identified by 16S rRNA gene sequencing. Whilst a wide variety of organisms were isolated, members of the SMG were the most prevalent bacteria cultured, and McKay agar allowed routine quantification of the SMG from 103 to >108 c.f.u. ml−1 directly from sputum. All members of the SMG were detected [Streptococcus anginosus (40.7 %), Streptococcus intermedius (34.3 %) and Streptococcus constellatus (25 %)] with an overall prevalence rate of 40.6 % in our adult CF population. Without exception, samples where SMG isolates were cultured at 107 c.f.u. ml−1 or greater were associated with pulmonary exacerbations. This study demonstrates that McKay agar can be used routinely to quantify the SMG from complex clinical samples.

scholarly journals Antibiotic Susceptibilities of Genetically Characterized Streptococcus milleri Group Strains

2001 ◽  
Vol 45 (5) ◽  
pp. 1511-1514 ◽  
Author(s):  
Michael Tracy ◽  
Anna Wanahita ◽  
Yevgeny Shuhatovich ◽  
Elizabeth A. Goldsmith ◽  
Jill E. Clarridge ◽  
...  
Keyword(s):  
16S Rrna Gene Sequencing ◽  
Rrna Gene ◽  
Beta Lactam ◽  
Streptococcus Anginosus ◽  
Beta Lactam Antibiotics ◽  
Streptococcus Constellatus ◽  
Antibiotic Susceptibilities ◽  
Streptococcus Milleri ◽  
Streptococcus Milleri Group ◽  
Rrna Gene Sequencing

ABSTRACT Previous studies of the antibiotic susceptibility ofStreptococcus milleri group organisms have distinguished among species by using phenotypic techniques. Using 44 isolates that were speciated by 16S rRNA gene sequencing, we studied the MICs and minimum bactericidal concentrations of penicillin, ampicillin, ceftriaxone, and clindamycin for Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus. None of the organisms was resistant to beta-lactam antibiotics, although a few isolates were intermediately resistant; one strain of S. anginosus was tolerant to ampicillin, and another was tolerant to ceftriaxone. Six isolates were resistant to clindamycin, with representation from each of the three species. Relatively small differences in antibiotic susceptibilities among species of the S. milleri group show that speciation is unlikely to be important in selecting an antibiotic to treat infection caused by one of these isolates.

scholarly journals Solitary submandibular soft tissue osteochondroma: A rare case report

2021 ◽  
pp. 106074
Author(s):  
Abdulrahman Z. Nakshabandi ◽  
Ahamd F. Alomar ◽  
Moayad Baazeem ◽  
Abdulrahman Alosaimi ◽  
Ibrahim O. Bello
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Rare Case ◽  
Rare Case Report
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