scholarly journals Spectrophotometric determination of amlodipineand nicardipine in pharmaceutical formulations viabinary complex formation with eosin Y

2012 ◽  
Author(s):  
Derayea
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Formulations ◽  
Eosin Y

Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions

2002 ◽  
Vol 28 (6) ◽  
pp. 1215-1220 ◽  
Author(s):  
Jadranka Kuljanin ◽  
Ivana Janković ◽  
Jovan Nedeljković ◽  
Dušica Prstojević ◽  
Valentina Marinković
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Formulations

scholarly journals Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y

2011 ◽  
Vol 5 (1) ◽  
Author(s):  
Mohamed I Walash ◽  
Fathalla F Belal ◽  
Manal I Eid ◽  
Samah Abo El Abass Mohamed
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Ion Pair ◽  
Eosin Y

scholarly journals USE OF ION ASSOCIATION COMPLEX FORMATION FOR THE SPECTROPHOTOMETRIC DETERMINATION OF ITOPRIDE HCL IN BULK AND ITS PHARMACEUTICAL PREPARATIONS

2016 ◽  
Vol 9 (1) ◽  
pp. 81
Author(s):  
P. V. Lakshmana Rao ◽  
C. Rambabu
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Pharmaceutical Preparations ◽  
Ion Association ◽  
Pharmaceutical Formulations ◽  
Spectrophotometric Methods ◽  
Itopride Hydrochloride ◽  
Soluble Ion ◽  
Association Complex

Objective: The authors report two simple, accurate and economic spectrophotometric methods A and B for the determination of Itopride hydrochloride in bulk and dosage forms.Methods: The proposed methods are based on the formation of chloroform soluble ion-associates in the presence of acidic dyes namely BPB (Method A) and BCP (Method B) exhibiting lmax at 418 and 418 nm respectively.Results: Beer’s law is found to be obeyed in the concentration range of 2.0-10.0 µg/ml and 2.0-10.0 µg/ml. The molar absorptivities are found to be 1.42x104 and 9.61x103L/mol. cm for methods A and B. These methods are successfully applied for the assay of Itopride hydrochloride in pharmaceutical formulations.

scholarly journals Spectrophotometric Determination of Ezetimibe

2010 ◽  
Vol 7 (1) ◽  
pp. 101-104 ◽  
Author(s):  
P. Baby Sudha Lakshmi ◽  
D. Ramchandran ◽  
C. Rambabu
Keyword(s):  
Complex Formation ◽  
Spectrophotometric Determination ◽  
Ferric Chloride ◽  
Spectrophotometric Method ◽  
Pharmaceutical Formulations ◽  
Complex Formation Reaction ◽  
Formation Reaction ◽  
Bulk Drug

Two simple, sensitive, selective and accurate spectro-photometric methods (Method A and Method B) for the determination of eztimibe in bulk drug and pharmaceutical formulations (tablets) have been described. Method A and B are based on the redox/complex formation reaction of drug with 1,10-phenanthroline and hexacyano-ferrate(III) in presence of ferric chloride to form coloured chromogens exhibitingλmaxat 510 and 740 nm respectively. The results of analysis for the two methods have been validated statistically and by recovery studies. The results are compared with those obtained using UV spectrophotometric method in alcohol at 231.7 nm.

scholarly journals Studying the association complex formation of atomoxetine and fluvoxamine with eosin Y and its application in their fluorimetric determination

2018 ◽  
Vol 5 (3) ◽  
pp. 170943 ◽  
Author(s):  
Sayed M. Derayea ◽  
Mahmoud A. Omar ◽  
Ahmed A. Abu-hassan
Keyword(s):  
Complex Formation ◽  
Pharmaceutical Formulations ◽  
Eosin Y ◽  
Fluorimetric Determination ◽  
Pharmaceutical Dosage Forms ◽  
Average Percentage ◽  
Binary Complexes ◽  
Spectrofluorimetric Method ◽  
Optimum Reaction

A simple, sensitive and non-extractive spectrofluorimetric method has been developed and validated for the determination of two psychoanaleptic drugs, atomoxetine and fluvoxamine, in pure forms and pharmaceutical dosage forms. The proposed method is based on the formation of binary complexes between eosin Y and the studied drugs in the presence of a Teorell–Stenhagen buffer. The quenching of the native fluorescence of eosin Y due to complex formation with the studied drugs was measured spectrofluorimetrically at 545 nm after excitation at 302 nm. At the optimum reaction conditions, the fluorescence quenching values (Δ F ) and concentrations were rectilinear over the concentration ranges of 0.2–2.2 and 0.3–2.2 µg ml −1 for atomoxetine and fluvoxamine, respectively. The developed method was successfully applied for the determination of the studied drugs in their pharmaceutical formulations with average percentage recoveries of 100.13 ± 0.66 and 99.69 ± 0.44 for atomoxetine and fluvoxamine, respectively ( n  = 5), without interference from common excipients.

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