scholarly journals Aging and longevity science: where are we in 2015?

Author(s):  
Alfred P Yoon ◽  
Christie P Yoon ◽  
Stephen Daane

Aging has been defined as the loss of function and ability to interact with the environment. The social perception of aging involves the inability to live independently due to loss of mobility, cognition, and sensory functions. Aging is a risk factor for pathology including cancer, cardiovascular disease, metabolic disease, and neurodegenerative disease. Due to these accompanying conditions, the esteem and respect once regarded for old age has been replaced by efforts to postpone, stop, or even reverse the aging process. Anti-aging medicine has gained popularity through media and marketing as companies have promoted an approach to delaying the side effects of aging through diet, exercise, supplements and hormonal therapy. The following is a comprehensive review of current research into potential strategies for anti-aging therapy and longevity, supported by current scientific and clinical research.

Author(s):  
Alfred P Yoon ◽  
Christie P Yoon ◽  
Stephen Daane

Aging has been defined as the loss of function and ability to interact with the environment. The social perception of aging involves the inability to live independently due to loss of mobility, cognition, and sensory functions. Aging is a risk factor for pathology including cancer, cardiovascular disease, metabolic disease, and neurodegenerative disease. Due to these accompanying conditions, the esteem and respect once regarded for old age has been replaced by efforts to postpone, stop, or even reverse the aging process. Anti-aging medicine has gained popularity through media and marketing as companies have promoted an approach to delaying the side effects of aging through diet, exercise, supplements and hormonal therapy. The following is a comprehensive review of current research into potential strategies for anti-aging therapy and longevity, supported by current scientific and clinical research.


2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
K. M. Rice ◽  
J. C. Fannin ◽  
C. Gillette ◽  
E. R. Blough

Cardiovascular disease is the leading cause of death in women in the United States. Aging is a primary risk factor for the development of cardiovascular disease as well as cardiovascular-related morbidity and mortality. Aging is a universal process that all humans undergo; however, research in aging is limited by cost and time constraints. Therefore, most research in aging has been done in primates and rodents; however it is unknown how well the effects of aging in rat models translate into humans. To compound the complication of aging gender has also been indicated as a risk factor for various cardiovascular diseases. This review addresses the systemic pathophysiology of the cardiovascular system associated with aging and gender for aging research with regard to the applicability of rat derived data for translational application to human aging.


2011 ◽  
Vol 81 (4) ◽  
pp. 240-244 ◽  
Author(s):  
Mary Ward ◽  
Carol P Wilson ◽  
J J Strain ◽  
Geraldine Horigan ◽  
John M. Scott ◽  
...  

Hypertension is a leading risk factor for cardiovascular disease (CVD) and stroke. A common polymorphism in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR), previously identified as the main genetic determinant of elevated homocysteine concentration and also recognized as a risk factor for CVD, appears to be independently associated with hypertension. The B-vitamin riboflavin is required as a cofactor by MTHFR and recent evidence suggests it may have a role in modulating blood pressure, specifically in those with the homozygous mutant MTHFR 677 TT genotype. If studies confirm that this genetic predisposition to hypertension is correctable by low-dose riboflavin, the findings could have important implications for the management of hypertension given that the frequency of this polymorphism ranges from 3 to 32 % worldwide.


Author(s):  
V. N. Krasnoshchekova ◽  
N. E. Ilyukhin

The functional shifts of the cardiovascular system at high intensity of the labor process for the prevention of psycho-emotional stress of the operating personnel and the prevention of the danger of emergency situations at power plants were studied.


2018 ◽  
Vol 27 (2) ◽  
pp. 1115-1126 ◽  
Author(s):  
Seul-Hee Lee ◽  
Ga-Ram Hong ◽  
Bong-Jo Kim ◽  
Eun-Hee Kim

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