scholarly journals Handling ethical problems in counterterrorism: An inventory of methods to support ethical decisionmaking

10.7249/rr251 ◽  
2014 ◽  
Author(s):  
Anais Reding ◽  
Anke Van Gorp ◽  
Kate Cox ◽  
Agnieszka Walczak ◽  
Chris Giacomantonio ◽  
...  
Keyword(s):  
Ethical Problems ◽  
Ethical Decisionmaking

scholarly journals Regulation and Ethics in Business: The Israeli Bank-Share Case

2001 ◽  
Vol 3 (3) ◽  
pp. 297-320
Author(s):  
Aviva Geva
Keyword(s):  
Phase Model ◽  
Business Sector ◽  
Ethical Problems ◽  
Business Regulation ◽  
Moral Problems ◽  
Ethical Norms ◽  
Ethical Decisionmaking

This article analyzes the early-1980s Israeli bank-share crash at different points of its development to demonstrate the vital contribution of managers' professional and personal ethical norms to a fruitful collaboration between government authorities and the business sector. After presenting the case and discussing pertinent problems of external versus internal business regulation, this article provides a phase model of ethical decisionmaking in business that reconstructs the moral problems faced by the major players and probes appropriate responses to these problems. The application of the model to the bank-share affair shows how different stages in the evolution of the crisis introduce different ethical problems, inviting different moral considerations and calling for different solutions.

My Ethical Problems with Book Publishers

2006 ◽  
Vol 15 (2) ◽  
pp. 8-10
Author(s):  
Russell Eisenman
Keyword(s):  
Ethical Problems ◽  
Book Publishers

Ethical boundaries of the legal regulation of conditions of carrying out genetic screening in prenatal diagnosis in Russia and abroad

2020 ◽  
Author(s):  
M.V. Medvedev , G.N. Suvorov , S.S. Zenin et all
Keyword(s):  
Prenatal Diagnosis ◽  
Great Britain ◽  
Legal System ◽  
Genetic Screening ◽  
Legal Status ◽  
Legal Regulation ◽  
Ethical Problems ◽  
Foreign Experience ◽  
Foreign Countries ◽  
General Scientific

Objectives. The purpose of this study is to study the essence of ethical problems that arise in the field of genetic screening for prenatal diagnosis (PND) and determine possible ways to overcome them by legal means, taking into account the existing foreign experience. Materials and methods. Normative legal acts and doctrinal sources of Great Britain, Germany, Ireland, France and Switzerland are studied. Methods used: General philosophical, General scientific, private scientific, special (structural-legal, comparative-legal, formal-legal). Results. Ways to resolve ethical problems that arise or may arise in the future as a result of genetic screening for PND, which can be applied within the Russian legal system, are proposed. Conclusions. It is stated that most of the identified ethical problems are related to the lack of normative consolidation of the legal status of the fetus. It is presumed that the beginning of ethics should serve as the guide for legislation in this area. At the same time, it is emphasized that the legal regulation of genetic screening in PND should be flexible enough to optimally ensure the interests of all participants in these relationships. In addition, in this direction, it seems appropriate to refer to the experience of a number of foreign countries, whose legislation provides for fairly strict requirements in the field of PND.

Creation of Cultures Containing Mutations Linked with Cardiovascular Diseases using Transfection and Genome Editing

2019 ◽  
Vol 25 (6) ◽  
pp. 693-699 ◽  
Author(s):  
Margarita A. Sazonova ◽  
Anastasia I. Ryzhkova ◽  
Vasily V. Sinyov ◽  
Marina D. Sazonova ◽  
Zukhra B. Khasanova ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Human Genome ◽  
Genetically Engineered ◽  
Metal Particles ◽  
Gene Gun ◽  
Ethical Problems ◽  
Dna Mutations ◽  
Human Dna ◽  
Transfection Method ◽  
The Creation

Objective: In this review article, we analyzed the literature on the creation of cultures containing mutations associated with cardiovascular diseases (CVD) using transfection, transduction and editing of the human genome. Methods: We described different methods of transfection, transduction and editing of the human genome, used in the literature. Results: We reviewed the researches in which the creation of сell cultures containing mutations was described. According to the literature, system CRISPR/Cas9 proved to be the most preferred method for editing the genome. We found rather promising and interesting a practically undeveloped direction of mitochondria transfection using a gene gun. Such a gun can direct a genetically-engineered construct containing human DNA mutations to the mitochondria using heavy metal particles. However, in human molecular genetics, the transfection method using a gene gun is unfairly forgotten and is almost never used. : Ethical problems arising from editing the human genome were also discussed in our review. We came to a conclusion that it is impossible to stop scientific and technical progress. It is important that the editing of the genome takes place under the strict control of society and does not bear dangerous consequences for humanity. To achieve this, the constant interaction of science with society, culture and business is necessary. Conclusion: he most promising methods for the creation of cell cultures containing mutations linked with cardiovascular diseases, were system CRISPR/Cas9 and the gene gun.

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