scholarly journals A rare case of Acute Febrile Neutrophilc Dermatosis – Sweet’s syndrome

2021 ◽  
Vol 12 (e) ◽  
pp. 1-4
Author(s):  
Ashwini Kodigehalli Chikkanna Swamy ◽  
Sandhaya Prasad ◽  
Anjan Kumar Patra

Sweet syndrome is an inflammatory dermatosis characterized by non-itchy, sometimes tender, erythematous plaques and papules most commonly distributed on the arms, upper body, head and neck. Histological findings include a dense dermal neutrophilic infiltrate with oedema. We report a case of 32year old female patient with solitary well defined erythematous edematous plaques with whitish scales at the centre of the lesion present over the extensor aspect of left forearm since 5days with sparing of palms , soles and mucosae. Laboratory investigations and histopathology were suggestive of Neutrophilic dermatoses (Sweet’s syndrome). This case was presented to highlight Atypical presentationof sweet syndrome – annular morphology and localization of lesions only over left forearm Therefore high index of suspicion is needed for its diagnosis in cases of solitary and isolated presentation along with necessary histopathological and laboratory investigations.

2016 ◽  
Vol 21 (1) ◽  
pp. 72-74 ◽  
Author(s):  
Allison K. Cinats ◽  
Richard M. Haber

Autoimmune hepatitis is a subtle diagnosis that has many diverse clinical presentations. It has been reported in the literature to occur concomitantly with pyoderma gangrenosum, a neutrophilic dermatosis. Sweet’s syndrome is another neutrophilic dermatosis and has been reported to be associated with autoimmune hepatitis in only 2 previous cases: 1 idiopathic and 1 drug induced. Here we report a third case in a 24-year-old woman diagnosed with Sweet’s syndrome in association with autoimmune hepatitis, documenting a possible trend between neutrophilic dermatoses and autoimmune hepatitis. The patient presented with a history of fever and tender, erythematous plaques on her legs. Skin biopsy of a plaque confirmed histiocytoid Sweet’s syndrome. Initial laboratory investigations revealed elevated transaminases, and liver biopsy confirmed autoimmune hepatitis. This case suggests autoimmune hepatitis should be considered as an association when investigating a patient with Sweet’s syndrome.


2016 ◽  
Vol 91 (5 suppl 1) ◽  
pp. 154-156
Author(s):  
Renata Marcarini ◽  
Raquel Nardelli de Araujo ◽  
Monisa Martins Nóbrega ◽  
Karina Bittencourt Medeiros ◽  
Alexandre Carlos Gripp ◽  
...  

2019 ◽  
Vol 12 (3) ◽  
pp. e228076 ◽  
Author(s):  
Umera Thebo ◽  
Sirisha Tummala ◽  
Samah Nassereddine ◽  
Faysal Haroun

A 46-year-old man with no significant medical history presented to haematology with symptoms of fatigue, dyspnoea on exertion and weight loss. Physical examination revealed a lesion on the right shin and splenomegaly. Labs were significant for leucocytosis with immature components, thrombocytosis and 3% peripheral blasts on smear. A bone marrow biopsy confirmed a diagnosis of myelofibrosis (MF). Dynamic International Prognosis Scoring system was 2. He was started on ruxolitnib, with decitabine added subsequently prior to definitive therapy with an allogenic haematopoietic stem cell transplant. His course with decitabine was complicated with febrile neutropaenia with multiple tender erythematous plaques unresponsive to antibacterial and antifungal coverage. A skin biopsy showed neutrophilic dermatitis, consistent with a diagnosis of Sweet’s syndrome (SS) and empirical treatment with glucocorticoids was initiated resulting in resolution of symptoms. This report reviews the literature for cases of SS in the setting of MF.


1976 ◽  
Vol 61 (3) ◽  
pp. 424-432 ◽  
Author(s):  
David E. Trentham ◽  
Alfonse T. Masi ◽  
George F. Bale

Sign in / Sign up

Export Citation Format

Share Document