scholarly journals Stimuli-responsive nanodrug self-assembled from amphiphilic drug-inhibitor conjugate for overcoming multidrug resistance in cancer treatment

Theranostics ◽  
2019 ◽  
Vol 9 (20) ◽  
pp. 5755-5768 ◽  
Author(s):  
Ping Huang ◽  
Guanchun Wang ◽  
Yue Su ◽  
Yongfeng Zhou ◽  
Wei Huang ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Cancer Treatment ◽  
Stimuli Responsive ◽  
Amphiphilic Drug ◽  
Self Assembled

scholarly journals Stimuli responsive dynamic transformations in supramolecular gels

2021 ◽  
Author(s):  
Santanu Panja ◽  
Dave J. Adams
Keyword(s):  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Stimuli Responsive ◽  
Dynamic Changes ◽  
Supramolecular Gels ◽  
Self Assembled ◽  
Physical And Chemical ◽  
And Chemical Properties

Stimuli responsive dynamic changes in the networks of self-assembled gels result in an alteration of physical and chemical properties of the gel with time.

Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy

Nano Today ◽  
2021 ◽  
Vol 38 ◽  
pp. 101119
Author(s):  
Masoud Delfi ◽  
Rossella Sartorius ◽  
Milad Ashrafizadeh ◽  
Esmaeel Sharifi ◽  
Yapei Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Targeted Delivery ◽  
Stimuli Responsive ◽  
Anti Cancer ◽  
Self Assembled

Functional nanoparticles of tea polyphenols for doxorubicin delivery in cancer treatment

2017 ◽  
Vol 5 (36) ◽  
pp. 7622-7631 ◽  
Author(s):  
Huaiying Zhang ◽  
Zeng Yi ◽  
Zhe Sun ◽  
Xiaomin Ma ◽  
Xudong Li
Keyword(s):  
Cancer Treatment ◽  
Therapeutic Agents ◽  
Tea Polyphenols ◽  
Stimuli Responsive ◽  
Anticancer Efficacy ◽  
Functional Nanoparticles ◽  
Prepared Nanoparticles ◽  
Doxorubicin Delivery

Simply-prepared nanoparticles of tea polyphenols are biocompatible, stimuli-responsive carriers for therapeutic agents, resulting in enhanced anticancer efficacy.

Reversal of Multidrug Resistance by Mitochondrial Targeted Self-Assembled Nanocarrier Based on Stearylamine

2013 ◽  
Vol 10 (6) ◽  
pp. 2426-2434 ◽  
Author(s):  
Zhiwen Zhang ◽  
Zeying Liu ◽  
Li Ma ◽  
Shijun Jiang ◽  
Yixin Wang ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Self Assembled

Recent Progress in Stimuli Responsive Intelligent Nano Scale Drug Delivery Systems: A special focus towards pH sensitive systems

2021 ◽  
Vol 22 ◽  
Author(s):  
Vaidevi Sethuraman ◽  
Kumar Janakiraman ◽  
Venkateshwaran Krishnaswami ◽  
Ruckmani Kandasamy
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Drug Delivery Systems ◽  
Disease Diagnosis ◽  
Delivery Systems ◽  
Ph Sensitive ◽  
Special Focus ◽  
Stimuli Responsive ◽  
Ph Variation ◽  
Responsive Systems

Abstract: Stimuli responsive nanocarriers are gaining much attention due to its versatile multifunctional activities including disease diagnosis and treatment. Recently, clinical applications of nano drug delivery systems for cancer treatment make a considerable challenge due to its limited cellular uptake, low bioavailability, poor targetability, stability issues, and unfavourable pharmacokinetics. To overcome these issues researchers are focussing on stimuli responsive systems. Nano carriers elicit its role through endogenous (pH, temperature, enzyme and redox) or exogenous (temperature, light, magnetic field, ultrasound) stimulus. These systems were designed to overcome the shortcomings such as non-specificity and toxicity associated with the conventional drug delivery systems. The pH variation between healthy cells and tumor microenvironment creates a platform towards the generation of pH sensitive nano delivery systems. Herein, we propose to present an overview of various internal and external stimuli responsive behavior based drug delivery systems. Herein the present review will focus specifically on the significance of various pH- responsive nanomaterials such as polymeric nanoparticles, nano micelles, inorganic based pH sensitive drug delivery carriers such as calcium phosphate nanoparticles, and carbon dots in cancer treatment. Moreover, this review elaborates the recent findings on pH based stimuli responsive drug delivery system with special emphasis towards our reported stimuli responsive systems for cancer treatment.

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