scholarly journals The homogeneity and heterogeneity of occurrence, characteristics, and prognosis in hepatocellular carcinoma patients with synchronous and metachronous bone metastasis

2022 ◽  
Vol 13 (2) ◽  
pp. 393-400
Author(s):  
Yanting Zhang ◽  
Yao Xu ◽  
Wenjuan Ma ◽  
Haixiao Wu ◽  
Guijun Xu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Occurrence Characteristics

scholarly journals Serum lnc34a is a potential prediction biomarker for bone metastasis in hepatocellular carcinoma patients

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Li Zhang ◽  
Hao Niu ◽  
Ping Yang ◽  
Jie Ma ◽  
Bao-Ying Yuan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Univariate Analysis ◽  
High Serum ◽  
Chain Reaction ◽  
Serum Samples ◽  
Early Screening ◽  
Expression Levels ◽  
Node Metastasis ◽  
Polymerase Chain

Abstract Background Early screening and intervention therapies are crucial to improve the prognosis of hepatocellular carcinoma (HCC) patients with bone metastasis. We aimed to identify serum lncRNA as a prediction biomarker in HCC bone metastasis. Methods The expression levels of lnc34a in serum samples from 157 HCC patients were detected by quantitative real-time polymerase chain reaction (PCR). Univariate analysis and multivariate analysis were performed to determine statistically significant variables. Results Expression levels of lnc34a in serum from HCC patients with bone metastasis were significantly higher than those without bone metastasis. The high expressions of lnc34a, vascular invasion and Barcelona Clinic Liver Cancer (BCLC) stage were associated with bone metastasis by analysis. Moreover, lnc34a expression was specifically associated with bone metastasis rather than lung or lymph node metastasis in HCC. Conclusions High serum lnc34a expression was a independent risk factor for developing bone metastasis in HCC.

scholarly journals RNF219/ α ‐Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications

2020 ◽  
pp. 2001961
Author(s):  
Shuxia Zhang ◽  
Yingru Xu ◽  
Chan Xie ◽  
Liangliang Ren ◽  
Geyan Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Skeletal Complications

scholarly journals RNF219/ α ‐Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications

2021 ◽  
Vol 8 (16) ◽  
pp. 2102956
Author(s):  
Shuxia Zhang ◽  
Yingru Xu ◽  
Chan Xie ◽  
Liangliang Ren ◽  
Geyan Wu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Skeletal Complications

scholarly journals MicroRNA-34a expression levels in serum and intratumoral tissue can predict bone metastasis in patients with hepatocellular carcinoma

Oncotarget ◽  
2016 ◽  
Vol 7 (52) ◽  
pp. 87246-87256 ◽  
Author(s):  
Zuo-Lin Xiang ◽  
Xiao-Mei Zhao ◽  
Li Zhang ◽  
Ping Yang ◽  
Jia Fan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Expression Levels

scholarly journals A Case of Canine Hepatocellular Carcinoma with Bone Metastasis

2008 ◽  
Vol 61 (6) ◽  
pp. 467-470
Author(s):  
Takanori SASAKI ◽  
Kenji TANI ◽  
Masanobu GORYO ◽  
Reeko SATO ◽  
Masaaki KATAYAMA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis

M2069 Analysis of Prognostic Factors of Hepatocellular Carcinoma Patients with Bone Metastasis

2009 ◽  
Vol 136 (5) ◽  
pp. A-478-A-479 ◽  
Author(s):  
Kosaku Moribata ◽  
Hideyuki Tamai ◽  
Yoshiyuki Mori ◽  
Naoki Shingaki ◽  
Tatsuya Shiraki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Prognostic Factors ◽  
Bone Metastasis

FDG-PET predicts outcomes of treated bone metastasis following palliative radiotherapy in patients with hepatocellular carcinoma

2014 ◽  
Vol 34 (7) ◽  
pp. 1118-1125 ◽  
Author(s):  
Seo Hee Choi ◽  
Jee Suk Chang ◽  
Yong Hyu Jeong ◽  
Youngin Lee ◽  
Mijin Yun ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Fdg Pet ◽  
Palliative Radiotherapy

2323 Bone Metastasis as Index Presentation of Hepatocellular Carcinoma

2019 ◽  
Vol 114 (1) ◽  
pp. S1295-S1295
Author(s):  
Eric O. Then ◽  
Andrew Ofosu ◽  
Vijay Gayam ◽  
Srikanth Maddika ◽  
Ali Chaudhri ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis

scholarly journals Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis

Gut ◽  
1998 ◽  
Vol 43 (4) ◽  
pp. 575-577 ◽  
Author(s):  
K Ohba ◽  
K Omagari ◽  
T Nakamura ◽  
N Ikuno ◽  
S Saeki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bone Metastasis ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Serum Levels ◽  
Tumour Necrosis Factor Α ◽  
Vertebral Bone ◽  
Old Japanese ◽  
Factor Α ◽  
Necrosis Factor

Spontaneous regression of hepatocellular carcinoma is a rare phenomenon. Abscopal regression of tumours resulting from the effect of irradiation of a tissue on a remote non-irradiated tissue is also rare. The case of a 76 year old Japanese man with hepatocellular carcinoma that regressed after radiotherapy for thoracic vertebral bone metastasis is described. Serum levels of tumour necrosis factor-α increased after radiotherapy. The findings suggests that such abscopal related regression may be associated with host immune response, involving cytokines such as tumour necrosis factor-α.

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