Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells

Naiyi Zou; Xueyuan Zhang; Shuguang Li; Youmei Li; Yan Zhao; Xingxiao Yang; Shuchai Zhu

doi:10.7150/jca.58023

Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells

Journal of Cancer ◽

10.7150/jca.58023 ◽

2021 ◽

Vol 12 (16) ◽

pp. 5013-5024

Author(s):

Naiyi Zou ◽

Xueyuan Zhang ◽

Shuguang Li ◽

Youmei Li ◽

Yan Zhao ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Radiation Resistance ◽

Akt Signaling ◽

Carcinoma Cells ◽

Akt Signaling Pathway

Download Full-text

HPV16 E6-E7 Induces Cancer Stem-like Cell Phenotypes and Chemoradioresistance in Esophageal Squamous Cell Carcinoma Through Activation of PI3K/Akt Signaling Pathway

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2016.06.2027 ◽

2016 ◽

Vol 96 (2) ◽

pp. E559

Author(s):

S. Che ◽

R. Xi ◽

S. Pan ◽

X. Chen ◽

B. Hui ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Hpv16 E6 ◽

Cell Phenotypes

Download Full-text

Knockdown of EphB3 inhibits cell proliferation partly through the AKT signaling pathway and represses epithelial-mesenchymal transition in esophageal squamous cell carcinoma

Translational Cancer Research ◽

10.21037/tcr-21-1567 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

Luqun Tang ◽

Lijun Wang ◽

Tao Yu ◽

Tongpeng Xu ◽

Lizhen Zhang ◽

...

Keyword(s):

Cell Proliferation ◽

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Epithelial Mesenchymal Transition ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Mesenchymal Transition

Download Full-text

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

Oncotarget ◽

10.18632/oncotarget.16333 ◽

2017 ◽

Vol 8 (24) ◽

pp. 38755-38766 ◽

Cited By ~ 35

Author(s):

Bin Li ◽

Wen Wen Xu ◽

Alfred King Y. Lam ◽

Yang Wang ◽

Hui-Fang Hu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Metastasis Therapy

Download Full-text

Mecambridine induces potent cytotoxic effects, autophagic cell death and modulation of the mTOR/PI3K/Akt signaling pathway in HSC‑3 oral squamous cell carcinoma cells

Oncology Letters ◽

10.3892/ol.2017.7321 ◽

2017 ◽

Cited By ~ 1

Author(s):

Na Lin ◽

Zhiping Li ◽

Deli Wang ◽

Kewen Zheng ◽

Yiyan Wu ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Death ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Carcinoma Cells ◽

Akt Signaling Pathway ◽

Cytotoxic Effects

Download Full-text

AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway

Journal of Cellular and Molecular Medicine ◽

10.1111/jcmm.15604 ◽

2020 ◽

Vol 24 (17) ◽

pp. 9999-10012

Author(s):

Zhan‐Fei Zhang ◽

Tie‐Jun Huang ◽

Xin‐Ke Zhang ◽

Yu‐Jie Xie ◽

Si‐Ting Lin ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway

Download Full-text

ITGA2 Overexpression Promotes Esophageal Squamous Cell Carcinoma Aggression via FAK/AKT Signaling Pathway

OncoTargets and Therapy ◽

10.2147/ott.s302028 ◽

2021 ◽

Vol Volume 14 ◽

pp. 3583-3596

Author(s):

Wei Huang ◽

Ju Zhu ◽

Haoming Shi ◽

Qingchen Wu ◽

Cheng Zhang

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway

Download Full-text

CircVRK1 regulates tumor progression and radioresistance in esophageal squamous cell carcinoma by regulating miR-624-3p/PTEN/PI3K/AKT signaling pathway

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2018.11.273 ◽

2019 ◽

Vol 125 ◽

pp. 116-123 ◽

Cited By ~ 11

Author(s):

Yunlong He ◽

E. Mingyan ◽

Chunbo Wang ◽

Guohui Liu ◽

Manru Shi ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Tumor Progression ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway

Download Full-text

Knockdown of HPIP Inhibits the Proliferation and Invasion of Head-and-Neck Squamous Cell Carcinoma Cells by Regulating PI3K/Akt Signaling Pathway

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504016x14612603423476 ◽

2016 ◽

Vol 24 (3) ◽

pp. 153-160 ◽

Cited By ~ 4

Author(s):

Yangjing Chen ◽

Ruimin Zhao ◽

Qian Zhao ◽

Yuan Shao ◽

Shaoqiang Zhang

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Carcinoma Cells ◽

Neck Squamous Cell Carcinoma ◽

Akt Signaling Pathway ◽

Proliferation And Invasion

Download Full-text

CDKN3 promotes cell proliferation, invasion and migration by activating the AKT signaling pathway in esophageal squamous cell carcinoma

Oncology Letters ◽

10.3892/ol.2019.11077 ◽

2019 ◽

Author(s):

Hanxu Yu ◽

Jun Yao ◽

Mingyu Du ◽

Jinjun Ye ◽

Xia He ◽

...

Keyword(s):

Cell Proliferation ◽

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Invasion And Migration ◽

And Migration

Download Full-text

Alpha-Tocopherol prevents esophageal squamous cell carcinoma by modulating PPARγ-Akt signaling pathway at the early stage of carcinogenesis

Oncotarget ◽

10.18632/oncotarget.21437 ◽

2017 ◽

Vol 8 (56) ◽

pp. 95914-95930 ◽

Cited By ~ 5

Author(s):

Miao Xu ◽

Hui Yang ◽

Qiannan Zhang ◽

Ping Lu ◽

Yongquan Feng ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Early Stage ◽

Akt Signaling ◽

Alpha Tocopherol ◽

Akt Signaling Pathway

Download Full-text