scholarly journals Methylated SFRP2 and SDC2 in stool specimens for Colorectal Cancer early detection: A cost-effective strategy for Chinese population

2021 ◽  
Vol 12 (9) ◽  
pp. 2665-2672
Author(s):  
Guodong Zhao ◽  
Xiaoyu Liu ◽  
Yi Liu ◽  
Yong Ma ◽  
Jun Yang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Early Detection ◽  
Chinese Population ◽  
Cost Effective ◽  
Effective Strategy ◽  
Cost Effective Strategy ◽  
Cancer Early Detection ◽  
Stool Specimens

scholarly journals Cost-Effectiveness Analysis of Local Ablation and Surgery for Liver Metastases of Oligometastatic Colorectal Cancer

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1507
Author(s):  
Matthias F. Froelich ◽  
Moritz L. Schnitzer ◽  
Nils Rathmann ◽  
Fabian Tollens ◽  
Marcus Unterrainer ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cost Effectiveness ◽  
Liver Metastases ◽  
Cost Effective ◽  
Comparable Efficacy ◽  
Base Case ◽  
Effective Strategy ◽  
Cost Effective Strategy ◽  
Life Years

Background: Colorectal cancer is among the most prevalent cancer entities worldwide, with every second patient developing liver metastases during their illness. For local treatment of liver metastases, a surgical approach as well as ablative treatment options, such as microwave ablation (MWA) and radiofrequency ablation (RFA), are available. The aim of this study is to evaluate the cost-effectiveness of RFA, MWA and surgery in the treatment of liver metastases of oligometastatic colorectal cancer (omCRC) that are amenable for all investigated treatment modalities. Methods: A decision analysis based on a Markov model assessed lifetime costs and quality-adjusted life years (QALY) related to the treatment strategies RFA, MWA and surgical resection. Input parameters were based on the best available and most recent evidence. Probabilistic sensitivity analyses (PSA) were performed with Monte Carlo simulations to evaluate model robustness. The percentage of cost-effective iterations was determined for different willingness-to-pay (WTP) thresholds. Results: The base-case analysis showed that surgery led to higher long-term costs compared to RFA and MWA (USD 41,848 vs. USD 36,937 vs. USD 35,234), while providing better long-term outcomes than RFA, yet slightly lower than MWA (6.80 vs. 6.30 vs. 6.95 QALYs for surgery, RFA and MWA, respectively). In PSA, MWA was the most cost-effective strategy for all WTP thresholds below USD 80,000 per QALY. Conclusions: In omCRC patients with liver metastases, MWA and surgery are estimated to provide comparable efficacy. MWA was identified as the most cost-effective strategy in intermediate resource settings and should be considered as an alternative to surgery in high resource settings.

A cost effective strategy to fabricate STA@PF@Cu2O hierarchical structure on wood surface: aimed at superhydrophobic modification

2021 ◽  
Vol 55 (2) ◽  
pp. 565-583
Author(s):  
Ke Zhan ◽  
Quanxiong Lu ◽  
Sengwei Xia ◽  
Congnan Guo ◽  
Sisi Zhao ◽  
...  
Keyword(s):  
Hierarchical Structure ◽  
Wood Surface ◽  
Cost Effective ◽  
Effective Strategy ◽  
Cost Effective Strategy

A cost effective strategy for managing GI bleeding secondary to peptic ulcer disease

1995 ◽  
Vol 108 (4) ◽  
pp. A18 ◽  
Author(s):  
I Hussain ◽  
WH Farrar ◽  
EJ Sofian ◽  
TF Bader ◽  
JD Strom ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Cost Effective ◽  
Effective Strategy ◽  
Gi Bleeding ◽  
Ulcer Disease ◽  
Cost Effective Strategy
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