scholarly journals The correlation between tumor size, lymph node status, distant metastases and mortality in rectal cancer patients without neoadjuvant therapy

2021 ◽  
Vol 12 (6) ◽  
pp. 1616-1622
Author(s):  
Dakui Luo ◽  
Zezhi Shan ◽  
Qi Liu ◽  
Sanjun Cai ◽  
Yanlei Ma ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Neoadjuvant Therapy ◽  
Cancer Patients ◽  
Tumor Size ◽  
Distant Metastases ◽  
Lymph Node Status ◽  
Node Status

scholarly journals Neopterin Is an Independent Prognostic Variable in Females with Breast Cancer

1999 ◽  
Vol 45 (11) ◽  
pp. 1998-2004 ◽  
Author(s):  
Christian Murr ◽  
Anton Bergant ◽  
Martin Widschwendter ◽  
Kurt Heim ◽  
Hans Schröcksnadel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Tumor Size ◽  
Distant Metastases ◽  
Cell Immune Response ◽  
Lymph Node Status ◽  
Risk Of Death ◽  
Node Status ◽  
Urinary Neopterin

Abstract Background: Neopterin, produced by human monocytes/macrophages upon stimulation by interferon-γ, is a sensitive marker for monitoring Th1-cell immune response in humans. In malignant diseases, the frequency of increases in neopterin in the serum and urine of patients depends on tumor stage and type. Methods: In a retrospective study comprising 129 females with breast cancer, urinary neopterin/creatinine ratios were measured at the time of diagnosis. Tumor characteristics were determined concomitantly. Results: Urinary neopterin was increased in 18% of the patients. It did not correlate with tumor size or lymph node status, but it was influenced by the presence of distant metastases (P <0.05) and by tumor differentiation (P = 0.01). When product-limit estimates were calculated after follow-up for up to 13 years (median follow-up, 56 months), the presence of distant metastases (P <0.001), neopterin (P <0.001), tumor size (P = 0.001), and lymph node status (P <0.01) were significant predictors of survival. By multivariate analysis, a combination of the variables presence of distant metastases (P <0.001), neopterin (P <0.01), and lymph node status (P <0.05) was found to jointly predict survival. In lymph node-negative patients without distant metastases, the relative risk of death associated with increased neopterin concentrations was 2.5 compared with patients with neopterin concentrations within the reference interval. Conclusion: Urinary neopterin provides additional prognostic information in patients with breast cancer.

scholarly journals Is T classification still correlated with lymph node status after preoperative chemoradiotherapy for rectal cancer?

Cancer ◽  
2006 ◽  
Vol 106 (8) ◽  
pp. 1694-1700 ◽  
Author(s):  
Duck-Woo Kim ◽  
Dae Yong Kim ◽  
Tae Hyun Kim ◽  
Kyung Hae Jung ◽  
Hee Jin Chang ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Preoperative Chemoradiotherapy ◽  
Lymph Node Status ◽  
Node Status ◽  
T Classification

Pathologic analysis of tumor size and lymph node status in multifocal/multicentric breast carcinoma

Cancer ◽  
2002 ◽  
Vol 94 (5) ◽  
pp. 1383-1390 ◽  
Author(s):  
Aleodor A. Andea ◽  
Tracie Wallis ◽  
Lisa A. Newman ◽  
David Bouwman ◽  
Jyotirmoy Dey ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Tumor Size ◽  
Lymph Node Status ◽  
Node Status ◽  
Pathologic Analysis

Sentinel Node Status and Tumor Characteristics: A Study of 234 Invasive Breast Carcinomas

2005 ◽  
Vol 129 (1) ◽  
pp. 82-84 ◽  
Author(s):  
Ying Cao ◽  
Gladell P. Paner ◽  
Prabha B. Rajan
Keyword(s):  
Lymph Node ◽  
Tumor Size ◽  
Lymphovascular Invasion ◽  
Frozen Section ◽  
Paraffin Section ◽  
Lymph Node Status ◽  
Axillary Lymph ◽  
Breast Carcinomas ◽  
Node Status ◽  
Size Grade

Abstract Context.—Axillary lymph node status is the most important prognostic factor in patients with breast cancer. Tumor size and lymph node status, the most reliable pathologic bases of the tumor staging system, are practical parameters for estimating survival status. With the advent of lymphatic mapping and sentinel node (SN) identification, there is potential for a more efficient and sensitive evaluation of the axillary lymph node status. Objective.—To correlate SN status with tumor size, grade, and lymphovascular invasion. Design.—We examined 234 patients with unifocal breast carcinomas measuring 25 mm or less as detected by preoperative ultrasound during the period May 1998 through December 2002. Sentinel nodes were examined by frozen section and paraffin section as per protocol. Results.—Of the 234 patients, SN was identified in 221 (94.5%). An average of 1.38 SNs were examined per patient. Seventy-seven of 221 patients were SN positive on paraffin section. Sixty-six (85.7%) of these 77 cases could be correctly diagnosed as positive for metastatic carcinoma on frozen section. Two cases reported as positive on paraffin section were reported as suspicious on frozen section. Logistic regression indicated that tumor size, grade, and lymphovascular invasion were all significantly associated with SN status (P < .001). Conclusions.—Tumor size, grade, and lymphovascular invasion were significantly associated with SN status in unifocal invasive breast carcinoma.

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