scholarly journals Adenosquamous Carcinoma of the Stomach: A Population-based Study from the SEER Database

2019 ◽  
Vol 10 (23) ◽  
pp. 5705-5713
Author(s):  
Yugang Ge ◽  
Linling Lin ◽  
Xiang Ma ◽  
Dakui Luo ◽  
Liang Shi ◽  
...  
Keyword(s):  
Adenosquamous Carcinoma ◽  
Population Based ◽  
Seer Database ◽  
Population Based Study ◽  
Carcinoma Of The Stomach

scholarly journals Prostatic Acid Phosphatase (PAP) Predicts Prostate Cancer Progress in a Population-Based Study: The Renewal of PAP?

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Huan Xu ◽  
Fubo Wang ◽  
Huizhen Li ◽  
Jin Ji ◽  
Zhi Cao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acid Phosphatase ◽  
Median Survival ◽  
Statistical Significance ◽  
Measurement Data ◽  
Population Based ◽  
Survival Duration ◽  
Seer Database ◽  
Invasion And Metastasis ◽  
Population Based Study

Objective. To characterize the disease progression and median survival of patients with prostate cancer (PCa) according to the prostatic-specific acid phosphatase (PAP) analysis in a population-based study from the Surveillance, Epidemiology, and End Results (SEER) database.Materials and Methods. Prostate cancer patients with completed PAP results were identified using the SEER database of the National Cancer Institute. The Mann-Whitney Sum test was utilized to compare the statistical significance for measurement data and ranked data. Data were stratified by ages, races, TNM Classification of Malignant Tumors (TNM), pathological grades, number of tumors, PAP, and survival duration. Multivariable logistic analysis was performed to identify predictors of the presence of invasion and metastases. Cox regression was analyzed for the factors associated with all-cause mortality and prostate cancer-specific mortality. Moreover, survival curve was used to detect the survival months. The unknown data were excluded from these tests.Results. In total, there are 5184 PAP+ patients and 3161 PAP- patients involved. The Mann-Whitney Sum test showed that slightly greater tumor size (P=0.03), elevated lymphatic (P=0.005) and distant (P<0.001) metastasis rate, higher pathological grade (P<0.001), localized tumor number (P<0.001), and shortened survival months (P<0.001) were observed in the PAP+ group compared with the PAP- group. In the multivariable logistic regression, invasion and metastasis Hazard Ratio (HR) were elevated significantly (P<0.001) in the PAP+ individuals. In the survival analysis, PAP- patients experienced the prolonged median survival. In the postsurgical patients, the survival months were still longer in PAP+ patients compared with the negative ones (P<0.001), though surgery prolonged the survival months of both groups. Survival months stratified by localized, invasion, and metastasis situations were analyzed. In the three stratified subgroups, the survival duration is significantly decreased in the PAP+ individuals in the localized PCa group (P<0.001) and the metastasis group (P=0.013).Conclusions. The findings of this study provide population-based estimates of the PCa progress and prognosis for patients with different PAP results, which may suggest a renewed period for the PAP.

scholarly journals Conditional Survival After Surgical Resection of Appendiceal Tumors: a Population-based Study

2021 ◽  
Author(s):  
Shutao Zhao ◽  
Chang Lu ◽  
Junan Li ◽  
Chao Zhang ◽  
Xudong Wang
Keyword(s):  
Prognostic Factors ◽  
Cox Regression ◽  
Population Based ◽  
Conditional Survival ◽  
Seer Database ◽  
Cancer Specific Survival ◽  
Population Based Study ◽  
Factors Affecting ◽  
Probability Of Survival ◽  
N Stage

Abstract Background: This study aimed to evaluate the conditional survival (CS) of appendiceal tumors (ATs) after surgery.Methods: A total of 3,031 patients with ATs who underwent surgery were included in the Surveillance Epidemiology and End Results (SEER) database from 2004 to 2016. A multivariate Cox regression model was used to analyze the prognostic factors affecting overall survival (OS) and cancer-specific survival (CSS). CS was used to calculate the probability of survival for another 3 years after the patient had survived x years. The formulas were COS3 = OS (x + 3) /OS (x), and CCS3 = CSS (x + 3)/CSS (x).Results: The 1-year, 3-year, and 5-year OSs for all patients were 95.6%, 83.3%, and 73.9%, respectively, while the 1-year, 3-year, and 5-year CSSs were 97.0%, 87.1%, and 79.9%, respectively. Age, grade, histology, N stage, carcinoembryonic antigen (CEA), and radiation were independent prognostic factors for OS and CSS. For patients that survived for 1 year, 3 years, and 5 years, their COS3s were 81.7%, 83.9%, and 87.0%, respectively. The CCS3s were 85.5%, 88.3%, and 92.0% respectively. In patients with poor clinicopathological factors, COS3 and CCS3 increased significantly, and the survival gap between OS and COS3, CSS and CCS3 was more obvious.Conclusions: CS for appendiceal tumors were dynamic and increased over time, especially in patients with poor prognosis.

Analysis of clinical characteristics and prognosis with cervical adenosquamous carcinoma: a large population-based study

2021 ◽  
Author(s):  
Yanan Ma ◽  
Aimei Zhao ◽  
Jinjuan Zhang ◽  
Sumei Wang ◽  
Jiandong Zhang
Keyword(s):  
Overall Survival ◽  
Regression Models ◽  
Clinical Characteristics ◽  
Cox Regression ◽  
Adenosquamous Carcinoma ◽  
Large Population ◽  
Population Based ◽  
Cancer Specific Survival ◽  
Population Based Study ◽  
Good Consistency

Objective: The target of this work was to analyze the clinical characteristics and construct nomograms to predict prognosis in patients with cervical adenosquamous carcinoma (ASC). Methods: A total of 788 ASC patients were tracked in the Surveillance, Epidemiology and End Results database. We compared the clinical characteristics and prognostic factors of ASC. Cox regression models were established, and nomograms constructed and verified. Results: ASC patients have lower age levels and higher histological grades than patients with squamous cell carcinoma. Nomograms were constructed with good consistency and feasibility in clinical practice. The C-indices for overall survival and cancer-specific survival were 0.783 and 0.787, respectively. Conclusion: ASC patients have unique clinicopathological and prognostic characteristics. Nomograms were successfully constructed and verified.

Solid Pseudopapillary Tumor of the Pancreas: A Large Population-Based Study Using the SEER Database

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S27
Author(s):  
Sajan Jiv Singh Nagpal ◽  
Dhruvika Mukhija ◽  
Harika Kandlakunta ◽  
Ayush Sharma ◽  
Shounak Majumder
Keyword(s):  
Large Population ◽  
Population Based ◽  
Solid Pseudopapillary Tumor ◽  
Seer Database ◽  
Population Based Study
Sign in / Sign up

Export Citation Format

Share Document