scholarly journals The Prevalence and associated Factors for Liver Metastases, Development and Prognosis in newly diagnosed Epithelial Ovarian Cancer: A large Population-Based Study from the SEER Database

2020 ◽  
Vol 11 (16) ◽  
pp. 4861-4869
Author(s):  
Iftikhar Hussain ◽  
Jiaqin Xu ◽  
Kui Deng ◽  
Noor-ul-Amin ◽  
Ce Wang ◽  
...  
2019 ◽  
Vol 29 (6) ◽  
pp. 1032-1037 ◽  
Author(s):  
Myrte Zijlstra ◽  
Maite Timmermans ◽  
Heidi Fransen ◽  
Maaike van der Aa ◽  
An Reyners ◽  
...  

ObjectivesA significant proportion of women with advanced-stage ovarian cancer receive no cancer-directed treatment and limited research has been devoted to this group. This population-based study aimed to gain insight into treatment patterns and trends in patients with advanced epithelial ovarian cancer in the Netherlands and the main reasons for deciding for no cancer-directed treatment.MethodsAll patients diagnosed with advanced epithelial ovarian cancer, International Federation of Gynecology and Obstetrics (FIGO) classification IIB−IV, between 2008 and 2016 were identified from the Netherlands Cancer Registry. Trends in the number of patients receiving cancer-directed treatment were analyzed. Multivariable logistic regression analysis was used to identify factors associated with no cancer-directed treatment. The main reasons for no cancer-directed treatment were analyzed.ResultsA total of 9303 patients were included, of whom 14% (n=1270) received no cancer-directed treatment while 67% (n=6218) received a combination of cytoreductive surgery and chemotherapy. Some 15% (n=1399) received chemotherapy only, and 4.5% (n=416) surgical resection or hormonal therapy only. The proportion of patients receiving no cancer-directed treatment was higher in 2014–2016 (16%, n=496/3175) compared with 2008–2010 (11%, n=349/3057, p<0.001). Associated factors with no cancer-directed treatment were higher age, FIGO stage IV, lower socioeconomic status, co-morbidity, and more recent years of diagnosis (p<0.001). Main reasons for no cancer-directed treatment were patient’s choice (40%) and poor condition of the patient (29%).ConclusionsThe proportion of patients with advanced epithelial ovarian cancer not receiving cancer-directed treatment has increased in the last decade in the Netherlands. Patient’s choice was the main reason for the decision to undergo no cancer-directed treatment, which indicates patient involvement in the decision-making process. The second most common reason for no cancer-directed treatment was poor condition of the patient, which might indicate careful selection of patients for treatment. Decision-making regarding treatment is well-considered, but more insight is needed, especially from the patient's perspective.


2020 ◽  
Vol 10 ◽  
Author(s):  
Haiyun Zhao ◽  
Fei Xu ◽  
Jiajia Li ◽  
Mengdong Ni ◽  
Xiaohua Wu

2020 ◽  
Vol 9 (11) ◽  
pp. 7044-7053
Author(s):  
Yufei Yuan ◽  
Ruoran Wang ◽  
Fanfan Guo ◽  
Yidan Zhang ◽  
Hongyan Wang ◽  
...  

2021 ◽  
Vol 12 (24) ◽  
pp. 7255-7265
Author(s):  
Gui-Min Hou ◽  
Chuang Jiang ◽  
Jin-peng Du ◽  
Chang Liu ◽  
Xiang-zheng Chen ◽  
...  

2014 ◽  
Vol 201 (5) ◽  
pp. 283-288 ◽  
Author(s):  
Satyamurthy Anuradha ◽  
Penelope M Webb ◽  
Penny Blomfield ◽  
Alison H Brand ◽  
Michael Friedlander ◽  
...  

2003 ◽  
Vol 91 (3) ◽  
pp. 608-615 ◽  
Author(s):  
Cynthia D O'Malley ◽  
Rosemary D Cress ◽  
Sharan L Campleman ◽  
Gary S Leiserowitz

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